DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment scu and Decr2

DIOPT Version :9

Sequence 1:	NP_523396.1	Gene:	scu / 32789	FlyBaseID:	FBgn0021765	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	NP_741993.1	Gene:	Decr2 / 64461	RGDID:	71002	Length:	292	Species:	Rattus norvegicus

Alignment Length:	265	Identity:	86/265 - (32%)
Similarity:	136/265 - (51%)	Gaps:	36/265 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MIKNAVSLVTGGASGLGRATAERLAKQGASVILADLPSSKGNEVAKEL----GDKVVFVPVDVTS 61
            ::::.|:.:|||.||:|...||...:.|...::......:.:|.||:|    |.:.:.:.:||..
  Rat    25 LLQDKVAFITGGGSGIGFRIAEIFMRHGCHTVIVSRSLPRVSEAAKKLVAATGKRCLPLSMDVRV 89

  Fly    62 EKDVSAALQTAKDKFGRLDLTVNCAG-----TATAVKTFNFNKNVAHRLEDFQRVININTVGTFN 121
            ...|.||:..|..:||::|:.:|||.     .|:|:   :||.        |:.|::|:|:||||
  Rat    90 PPAVMAAVDQALKEFGKIDILINCAAGNFLCPASAL---SFNA--------FKTVVDIDTLGTFN 143

  Fly   122 VIRLSAGLMGANEPNQDGQRGVIVNTASVAAFDGQIGQAAYSASKAAVVGMTLPIARDLSTQGIR 186
            |.|:      ..|.......|||||..:..:..||:.|....|:||||..||..:|.:...|.||
  Rat   144 VSRV------LYEKFFRDHGGVIVNITATLSMRGQVLQLHAGAAKAAVDAMTRHLAVEWGPQNIR 202

  Fly   187 ICTIAPG-LFNTPMLAAL--PEKVRTFLAKSIPFPQRLGEPSEYAHLVQAIY-ENPL---LNGEV 244
            :.::||| :..|..|..|  |:....|...|.|.| |||..:|.||.|  :| .:||   ::|.|
  Rat   203 VNSLAPGAISGTEGLRRLGGPKASSKFKYLSSPIP-RLGTKTEIAHSV--LYLASPLASYVSGIV 264

  Fly   245 IRIDG 249
            :.:||
  Rat   265 LVVDG 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scu	NP_523396.1	HSD10-like_SDR_c	3..255	CDD:187629	86/263 (33%)
Decr2	NP_741993.1	TER_DECR_SDR_a	26..273	CDD:187627	86/264 (33%)
		Substrate binding. /evidence=ECO:0000250	126..128		0/1 (0%)
		Microbody targeting signal	290..292
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910