DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment scu and rdh14

DIOPT Version :9

Sequence 1:	NP_523396.1	Gene:	scu / 32789	FlyBaseID:	FBgn0021765	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	NP_001017231.1	Gene:	rdh14 / 549985	XenbaseID:	XB-GENE-1018384	Length:	323	Species:	Xenopus tropicalis

Alignment Length:	237	Identity:	61/237 - (25%)
Similarity:	102/237 - (43%)	Gaps:	46/237 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MIKNAVSLVTGGASGLGRATAERLAKQGASVILADLPSSKGNEVAKEL----GDK--VVFVPVDV 59
            :::....::||...|:|:|||..|.||.|.||||.....:..|.|.||    |::  :|...:|:
Frog    39 LMRGKTVIITGANCGIGKATAAELVKQEARVILACRDQGRAEEAAAELRREAGERGEIVIKQLDL 103

  Fly    60 TSEKDVSAALQTAKDKFGRLDLTVNCAGTATAVKTFNFNKNVAHRLED-FQRVININTVGTFNVI 123
            .|.:.|....|....:..|||:.:|.||......|         :.|| |:....:|.:|.|.:.
Frog   104 GSLQSVRRFCQEVLKEEPRLDVLINNAGVFQCPYT---------KTEDGFEMQFGVNHLGHFLLT 159

  Fly   124 RLSAGLMGANEPNQDGQRGVIVNTASVAAFDGQIG------------QAAYSASKAAVVGMTLPI 176
            ....||:.::.|::     ::|.::.:..: |:|.            ...||.||.|.:..|..:
Frog   160 HHLLGLLKSSAPSR-----IVVVSSKLYKY-GEINFDDLNSEKSYSRSFGYSRSKLANILFTREL 218

  Fly   177 ARDLSTQGIRICTIAPGLFNTPMLAALPEKVRTFLAKSIPFP 218
            |..|...|:.:..:.||:            |||.|.:.|..|
Frog   219 ASRLEGTGVTVNALHPGI------------VRTNLGRHINIP 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scu	NP_523396.1	HSD10-like_SDR_c	3..255	CDD:187629	61/235 (26%)
rdh14	NP_001017231.1	NADB_Rossmann	42..315	CDD:389744	61/234 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910