DRSC/TRiP Functional Genomics Resources

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Protein Alignment scu and HSD17B11

DIOPT Version :9

Sequence 1:NP_523396.1 Gene:scu / 32789 FlyBaseID:FBgn0021765 Length:255 Species:Drosophila melanogaster
Sequence 2:NP_057329.3 Gene:HSD17B11 / 51170 HGNCID:22960 Length:300 Species:Homo sapiens


Alignment Length:247 Identity:64/247 - (25%)
Similarity:98/247 - (39%) Gaps:32/247 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 IKNAVSLVTGGASGLGRATAERLAKQGASVILADLPSSKGNEVA---KELGDKVVFVPVDVTSEK 63
            :...:.|:||...|:||.||...||..:.::|.|:......|.|   |.||.||....||.::.:
Human    34 VTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNRE 98

  Fly    64 DVSAALQTAKDKFGRLDLTVNCAGTATAVKTFNFNKNVAHRLEDFQRVININTVGTFNVIRLSAG 128
            |:.::.:..|.:.|.:.:.||.||.......|      |.:....::...:|.:..|...:....
Human    99 DIYSSAKKVKAEIGDVSILVNNAGVVYTSDLF------ATQDPQIEKTFEVNVLAHFWTTKAFLP 157

  Fly   129 LMGANEPNQDGQRGVIVNTASVAAFDGQIGQAAYSASKAAVVGMTLPIARDLST---QGIRICTI 190
            .|..|      ..|.||..||.|.........||.:||.|.||....:..:|:.   .|::...:
Human   158 AMTKN------NHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCL 216

  Fly   191 APGLFNT-----------PMLAALPEKVRTFLAKSIPFPQR-LGEPSEYAHL 230
            .|...||           |.|.  ||:|...|...|...|: :..||..|.|
Human   217 CPNFVNTGFIKNPSTSLGPTLE--PEEVVNRLMHGILTEQKMIFIPSSIAFL 266

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
scuNP_523396.1 HSD10-like_SDR_c 3..255 CDD:187629 64/246 (26%)
HSD17B11NP_057329.3 17beta-HSDXI-like_SDR_c 38..277 CDD:187598 64/243 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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