DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment scu and hsd17b10

DIOPT Version :9

Sequence 1:	NP_523396.1	Gene:	scu / 32789	FlyBaseID:	FBgn0021765	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	NP_001006098.1	Gene:	hsd17b10 / 450078	ZFINID:	ZDB-GENE-041010-201	Length:	260	Species:	Danio rerio

Alignment Length:	254	Identity:	172/254 - (67%)
Similarity:	207/254 - (81%)	Gaps:	0/254 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 IKNAVSLVTGGASGLGRATAERLAKQGASVILADLPSSKGNEVAKELGDKVVFVPVDVTSEKDVS 66
            :|..|.|||||||||||||.|||.|.|||.::.|||||.|::||..|||:..|.|.|||||.||.
Zfish     7 VKGMVGLVTGGASGLGRATVERLIKHGASAVILDLPSSDGHKVAAALGDRCAFAPTDVTSESDVR 71

  Fly    67 AALQTAKDKFGRLDLTVNCAGTATAVKTFNFNKNVAHRLEDFQRVININTVGTFNVIRLSAGLMG 131
            :||..||:|:|::||.|||||.|.||||:||.|::.|.||||.|||.:|..||||||||:.|.||
Zfish    72 SALDLAKEKYGKVDLAVNCAGIAVAVKTYNFKKDLPHSLEDFTRVITVNIAGTFNVIRLAVGEMG 136

  Fly   132 ANEPNQDGQRGVIVNTASVAAFDGQIGQAAYSASKAAVVGMTLPIARDLSTQGIRICTIAPGLFN 196
            .|||:.||.||.|||||||||:|||:|||||||||..:|||||||||||:..|||:.|||||||.
Zfish   137 KNEPDADGHRGCIVNTASVAAYDGQVGQAAYSASKGGIVGMTLPIARDLAPMGIRVVTIAPGLFA 201

  Fly   197 TPMLAALPEKVRTFLAKSIPFPQRLGEPSEYAHLVQAIYENPLLNGEVIRIDGALRMMP 255
            ||:||.|||||::|||:.:|||.|||:|:|:||||.:|.|||::||||||:|||:||.|
Zfish   202 TPLLAGLPEKVQSFLARQVPFPSRLGDPAEFAHLVTSIAENPMINGEVIRLDGAIRMQP 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scu	NP_523396.1	HSD10-like_SDR_c	3..255	CDD:187629	171/251 (68%)
hsd17b10	NP_001006098.1	fabG	6..259	CDD:235500	170/251 (68%)
hsd17b10	NP_001006098.1	HSD10-like_SDR_c	8..260	CDD:187629	171/251 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592581
Domainoid	1	1.000	278	1.000	Domainoid score	I1684
eggNOG	1	0.900	-	-		E1_KOG1199
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68403
Inparanoid	1	1.050	357	1.000	Inparanoid score	I2198
OMA	1	1.010	-	-		QHG63573
OrthoDB	1	1.010	-	-		D1074094at2759
OrthoFinder	1	1.000	-	-		FOG0007902
OrthoInspector	1	1.000	-	-		oto40921
orthoMCL	1	0.900	-	-		OOG6_102935
Panther	1	1.100	-	-	LDO	PTHR43658
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3751
SonicParanoid	1	1.000	-	-		X3886
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800