DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment scu and Wwox

DIOPT Version :9

Sequence 1:	NP_523396.1	Gene:	scu / 32789	FlyBaseID:	FBgn0021765	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	NP_001285735.1	Gene:	Wwox / 34090	FlyBaseID:	FBgn0031972	Length:	409	Species:	Drosophila melanogaster

Alignment Length:	205	Identity:	43/205 - (20%)
Similarity:	80/205 - (39%)	Gaps:	27/205 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 SLVTGGASGLGRATAERLAKQGASVILADLPSSKGNEVAKELG-------DKVVFVPVDVTSEKD 64
            :|:||...|:|..||..||..|..:|.|....|......:.:.       .:..|..:|::|.:.
  Fly   124 ALITGANCGIGYETARSLAHHGCEIIFACRNRSSAEAAIERIAQERPAARSRCRFAALDLSSLRS 188

  Fly    65 VSAALQTAKDKFGRLDLTVNCAG--------TATAVKTFNFNKNVAHRLEDFQRVININTVGTFN 121
            |...::..|.....:|..:..||        |...::|   ...|:| |..|...:.:.|:..:.
  Fly   189 VQRFVEEIKQSVSHIDYLILNAGVFALPYTRTVDGLET---TFQVSH-LSHFYLTLQLETLFDYK 249

  Fly   122 ---VIRLSAGLMGANEPNQDGQRGVIVNTASVAAFDGQIGQAAYSASKAAVVGMTLPIARDLSTQ 183
               ::..|.....||.|.::    :.|:..|... :......||:.:|...|.....:|:....:
  Fly   250 TRIIVLSSESHRFANLPVEN----LAVHHLSPPP-EKYWSMMAYNNAKLCNVLFAQELAQRWKQR 309

  Fly   184 GIRICTIAPG 193
            ||.:.::.||
  Fly   310 GISVFSLHPG 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scu	NP_523396.1	HSD10-like_SDR_c	3..255	CDD:187629	43/205 (21%)
Wwox	NP_001285735.1	WW	13..43	CDD:197736
		WW	54..86	CDD:197736
		PRK06196	104..402	CDD:235736	43/205 (21%)
		human_WWOX_like_SDR_c-like	121..402	CDD:187669	43/205 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447631
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840