Protein Alignment scu and HSD11B1

DIOPT Version :9

• Sequence 1: NP_523396.1
• Gene: scu / 32789
• FlyBaseID: FBgn0021765
• Length: 255
• Species: Drosophila melanogaster
• Sequence 2: NP_001193670.1
• Gene: HSD11B1 / 3290
• HGNCID: 5208
• Length: 292
• Species: Homo sapiens
• Alignment Length: 216
• Identity: 55/216 - (25%)
• Similarity: 91/216 - (42%)
• Gaps: 45/216 - (20%)

  Fly     1 MIKNAVSLVTGGASGLGRATAERLAKQGASVILADLPSSKGNEVAKELGDKVV--FVPVDVTSEK 63
            |::....:|||.:.|:||..|..|||.||.|::        ...:||...|||  .:.:...|..
Human    31 MLQGKKVIVTGASKGIGREMAYHLAKMGAHVVV--------TARSKETLQKVVSHCLELGAASAH 87

  Fly    64 DVSAALQ--TAKDKF--------GRLDLTVNCAGTATAVKTFNFNKNVAHRLEDFQRVININTVG 118
            .::..::  |..::|        |.||:.:....|.|::..|:         :|...|.....|.
Human    88 YIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFH---------DDIHHVRKSMEVN 143

  Fly   119 TFNVIRLSAGLMGANEPNQDGQRGVIVNTASVAAFDGQIGQ---AAYSASKAAVVGMTLPIARDL 180
            ..:.:.|:...:    |......|.||..:|:|   |::..   |||||||.|:.|....|.::.
Human   144 FLSYVVLTVAAL----PMLKQSNGSIVVVSSLA---GKVAYPMVAAYSASKFALDGFFSSIRKEY 201

  Fly   181 STQ----GIRICTIAPGLFNT 197
            |..    .|.:|.:  ||.:|
Human   202 SVSRVNVSITLCVL--GLIDT 220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scu	NP_523396.1	HSD10-like_SDR_c	3..255	CDD:187629	54/214 (25%)
HSD11B1	NP_001193670.1	11beta-HSD1_like_SDR_c	32..279	CDD:187593	54/215 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910