DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment scu and Mfe2

DIOPT Version :9

Sequence 1:	NP_523396.1	Gene:	scu / 32789	FlyBaseID:	FBgn0021765	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	NP_001285318.1	Gene:	Mfe2 / 32582	FlyBaseID:	FBgn0030731	Length:	598	Species:	Drosophila melanogaster

Alignment Length:	238	Identity:	62/238 - (26%)
Similarity:	101/238 - (42%)	Gaps:	63/238 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VSLVTGGASGLGRATAERLAKQGASVILADLPSSKG-------------NEVAKELGDKVVFVPV 57
            |::|||..:||||..|...|::||.|::.||..:..             :|:.|..|:.|    .
  Fly    14 VAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADIVVDEIRKAGGEAV----A 74

  Fly    58 DVTSEKDVSAALQTAKDKFGRLDLTVNCAG---TATAVKTFNFNKNVAHRLEDFQRVININTVGT 119
            |..|..|.:..::||...|||:|:.||.||   ..:.|||..         :|:..|.:::..|:
  Fly    75 DYNSVIDGAKVIETAIKAFGRVDILVNNAGILRDRSLVKTSE---------QDWNLVNDVHLKGS 130

  Fly   120 FNVIRLSAGLMGANEPNQDGQRGVIVNTASVAAFDGQIGQAAYSASKAAVVGMT----------- 173
            |...:.:...|      :....|.|:.|:|.:...|..||..|:|:|..::|:.
  Fly   131 FKCTQAAFPYM------KKQNYGRIIMTSSNSGIYGNFGQVNYTAAKMGLIGLANTVAIEGARNN 189

  Fly   174 ------LPIARDLSTQGIRICTIAPGLFN-------TPMLAAL 203
                  :|.|....|:||    :...|||       .|::|.|
  Fly   190 VLCNVIVPTAASRMTEGI----LPDILFNELKPKLIAPVVAYL 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scu	NP_523396.1	HSD10-like_SDR_c	3..255	CDD:187629	62/238 (26%)
Mfe2	NP_001285318.1	hydroxyacyl-CoA-like_DH_SDR_c-like	8..257	CDD:187611	62/238 (26%)
		PRK07791	11..248	CDD:236099	62/238 (26%)
		PLN02864	315..598	CDD:178455
		hot_dog	<383..442	CDD:294345
		HDE_HSD	471..592	CDD:239532
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447626
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840