DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment scu and Hsd17b10

DIOPT Version :9

Sequence 1:	NP_523396.1	Gene:	scu / 32789	FlyBaseID:	FBgn0021765	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	NP_058043.3	Gene:	Hsd17b10 / 15108	MGIID:	1333871	Length:	261	Species:	Mus musculus

Alignment Length:	254	Identity:	172/254 - (67%)
Similarity:	207/254 - (81%)	Gaps:	0/254 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 IKNAVSLVTGGASGLGRATAERLAKQGASVILADLPSSKGNEVAKELGDKVVFVPVDVTSEKDVS 66
            :|..|::|||||||||.|||:||..|||:.:|.|:|.|:|...||:||:..:|.|.:|||||::.
Mouse     8 VKGLVAVVTGGASGLGLATAKRLVGQGATAVLLDVPDSEGEAQAKKLGESCIFAPANVTSEKEIQ 72

  Fly    67 AALQTAKDKFGRLDLTVNCAGTATAVKTFNFNKNVAHRLEDFQRVININTVGTFNVIRLSAGLMG 131
            |||..||:||||:|:.|||||.|.|:||::..||..|.|||||||||:|.:||||||||.||.||
Mouse    73 AALTLAKEKFGRIDVAVNCAGIAVAIKTYHQKKNKIHTLEDFQRVINVNLIGTFNVIRLVAGEMG 137

  Fly   132 ANEPNQDGQRGVIVNTASVAAFDGQIGQAAYSASKAAVVGMTLPIARDLSTQGIRICTIAPGLFN 196
            .|||:|.||||||:||||||||:||:|||||||||..:|||||||||||:..|||:.|||||||.
Mouse   138 QNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPTGIRVVTIAPGLFA 202

  Fly   197 TPMLAALPEKVRTFLAKSIPFPQRLGEPSEYAHLVQAIYENPLLNGEVIRIDGALRMMP 255
            ||:|..||||||.|||..:|||.|||:|:|||||||.|.|||.|||||||:|||:||.|
Mouse   203 TPLLTTLPEKVRNFLASQVPFPSRLGDPAEYAHLVQTIIENPFLNGEVIRLDGAIRMQP 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scu	NP_523396.1	HSD10-like_SDR_c	3..255	CDD:187629	171/251 (68%)
Hsd17b10	NP_058043.3	fabG	7..260	CDD:235500	170/251 (68%)
Hsd17b10	NP_058043.3	HSD10-like_SDR_c	9..261	CDD:187629	171/251 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847342
Domainoid	1	1.000	265	1.000	Domainoid score	I1896
eggNOG	1	0.900	-	-		E1_KOG1199
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68403
Inparanoid	1	1.050	348	1.000	Inparanoid score	I2286
Isobase	1	0.950	-	0.913288	Normalized mean entropy	S1300
OMA	1	1.010	-	-		QHG63573
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007902
OrthoInspector	1	1.000	-	-		oto92246
orthoMCL	1	0.900	-	-		OOG6_102935
Panther	1	1.100	-	-	LDO	PTHR43658
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3751
SonicParanoid	1	1.000	-	-		X3886
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.740