DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment scu and hsd17b3

DIOPT Version :9

Sequence 1:	NP_523396.1	Gene:	scu / 32789	FlyBaseID:	FBgn0021765	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	XP_012827001.1	Gene:	hsd17b3 / 101730254	XenbaseID:	XB-GENE-986068	Length:	302	Species:	Xenopus tropicalis

Alignment Length:	225	Identity:	53/225 - (23%)
Similarity:	98/225 - (43%)	Gaps:	35/225 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 SLVTGGASGLGRATAERLAKQGASVILADLPSSKGNEVAKEL----GDKVVFVPVDVTSE---KD 64
            ::|||...|:|:|.:..||.:|.::::......|...||.::    |..|..:..|.|.:   :.
Frog    47 AVVTGAGDGIGKAYSTELANRGMNIVMISRTLEKMQAVAMDIEQSTGKNVKIIQADFTKDNIYEH 111

  Fly    65 VSAALQTAKDKFGRLDLTVNCAGTATAVKTFNFNKNVAHRL---EDFQRVININTVGTFNVIRLS 126
            :...|:..|     :.:.:|..|..       .|.:....|   ::.:.|||.|...|..:.|:.
Frog   112 IEEGLKGLK-----IGILINNVGML-------HNPDPCRFLSGPDNDKNVINCNITSTIKMTRII 164

  Fly   127 AGLMGANEPNQDGQRGVIVNTAS-VAAFDGQIGQAAYSASKAAVVGMTLPIARDLSTQGIRICTI 190
            ...|      :..:.|:|:|.:| |..|...: .|.||||||.|...:..:..:..::||.|..:
Frog   165 LKQM------EKRKSGLILNISSAVGRFPCPL-YAVYSASKAFVTTFSKALQAEYKSKGIIIQAV 222

  Fly   191 APGLFNTPMLA-----ALPEKVRTFLAKSI 215
            .|...:|||..     |:.::...|:.:|:
Frog   223 TPYGVSTPMTRNARTNAITKRPVDFVRQSL 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scu	NP_523396.1	HSD10-like_SDR_c	3..255	CDD:187629	53/225 (24%)
hsd17b3	XP_012827001.1	17beta-HSD1_like_SDR_c	44..281	CDD:187614	53/225 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910