DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7206 and Swt1

DIOPT Version :9

Sequence 1:	NP_996499.1	Gene:	CG7206 / 32788	FlyBaseID:	FBgn0030892	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	NP_001099430.1	Gene:	Swt1 / 289088	RGDID:	1308695	Length:	910	Species:	Rattus norvegicus

Alignment Length:	429	Identity:	104/429 - (24%)
Similarity:	181/429 - (42%)	Gaps:	72/429 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SLGGESKHTPKSSNLRPLDDDQLVRIISTPRPSNGVSQHPAQDRLKRLQGQLKRVQDNEKEQGTT 66
            ::|.:..:..||.:|..:..|...:.....:..|..|. ..|.::|.|:.:......:|:.:..|
  Rat   146 NIGSKLDYEIKSRSLIKITKDMKSKAEDQTKEKNWPSL-LIQKKMKELKKEKNNKDSSEELEKCT 209

  Fly    67 K----------RITHSSSASRRSSASTSTPQRLLKFPPKVAMNAWEKPKALVDANRLKAGRTQTA 121
            |          .|......|.|...|...|::......|:|    |:....||:::.|:  .|..
  Rat   210 KNQPPQNYNFSNIIKEPLESGRKKISFKIPKKSSSALQKLA----EENIFSVDSSKSKS--KQEG 268

  Fly   122 YQRLMLLRASL-----QQKQLYEE--RNNNIVAKINEEVIEKQPEACNITNPSAFDGSTASDMEV 179
            .:.|...|.||     :.:.|:.|  ..:.:..:..|..:|.|.     ||.|....:.|...|.
  Rat   269 KEHLQSHRVSLSLERHKTENLFSESTHKHTVCERRREYHLEHQE-----TNGSDSKENCAQSFET 328

  Fly   180 EPMEWQESIEEEAAQNDQDEAKKGDDTLLMLPAESIEEEA-PQKGQDEAKE----EDDT-----I 234
             |.   .|:..|..|:..:|.:..::.......:|::..| |..|:..:.|    |||.     |
  Rat   329 -PC---SSVSSETIQDTDEEMQIVEELHAARVGKSVDLPAGPPSGELMSMEIDLVEDDVHSSADI 389

  Fly   235 LMLQAADAEELPPRLEDYMYFVLDTNVLIHNHKFVERLTDVVLPGTVGSMLYLPYIVIKELDKLK 299
            |...|:|.:         :..|:|||:|:::.|||..|....:||....:|.:|::|::|||::|
  Rat   390 LSNTASDKK---------LLIVIDTNILMNHLKFVRILKTTEIPGFDTLVLIIPWVVMQELDRMK 445

  Fly   300 SKYQSDCLQRV--IAMRAIRFLNTK--------FDESFQIQAQSALEEADHLIKIDCPDDSILNC 354
            :   ...|:.|  .|:.||.|:|..        :.:|.|:.:|.....:|     :..||.:|.|
  Rat   446 A---GKLLKHVQHKAVPAIHFINDSLKSQDRKLWGQSLQLASQKLYGLSD-----ENNDDRVLKC 502

  Fly   355 CLQLQAQVP--HMILLTNDANLRLKANASNIQVSCRSDL 391
            |||.|...|  .:||.|:|.|||.|...|.::...:.:|
  Rat   503 CLQYQELFPCSLVILCTDDRNLRSKGLISGVKSLSKEEL 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7206	NP_996499.1	PIN_Smg5-Smg6-like	254..392	CDD:189050	48/150 (32%)
Swt1	NP_001099430.1	PIN_Smg5-Smg6-like	400..544	CDD:189050	48/150 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352913
Domainoid	1	1.000	66	1.000	Domainoid score	I9754
eggNOG	1	0.900	-	-		E1_KOG4689
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007053
OrthoInspector	1	1.000	-	-		oto98189
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.740