Protein Alignment CG7206 and smg-6

DIOPT Version :9

• Sequence 1: NP_996499.1
• Gene: CG7206 / 32788
• FlyBaseID: FBgn0030892
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_497566.3
• Gene: smg-6 / 175367
• WormBaseID: WBGene00004884
• Length: 1241
• Species: Caenorhabditis elegans
• Alignment Length: 573
• Identity: 106/573 - (18%)
• Similarity: 179/573 - (31%)
• Gaps: 243/573 - (42%)

  Fly    12 KSSNLRPLDDDQLVRIISTPRPSNGVSQ-----------HP---AQDRLK--------------- 47
            :.:.|.|:|      ::|..|....:.:           ||   |:||||
 Worm   704 RRARLVPVD------VLSRQRQKRVIDEFFCLTRALACSHPYEVAKDRLKQRIDAMRTKVAKYQP 762

  Fly    48 ---------RLQGQ-LKRVQ----------DNEKEQGTTKRIT---------------------- 70
                     :.||. |:|:|          ....:.||.:||.
 Worm   763 VLDKESGIVKEQGNVLRRLQRIRQIWIHPITETSQDGTGERIVDDVLVHFMEHSKAKLHRRAVSY 827

  Fly    71 ---------------HSSSASRRS----------SASTSTPQRLLKFPPK---VAMNAWEKPKAL 107
                           |..|.|.|:          |.:..:..:|:||...   .|...::|....
 Worm   828 LCDTFGMLVTKIGMDHFESVSERAFGLLYASLSKSETDFSADQLVKFSAMFIYAAQVNFDKSTPS 892

  Fly   108 VDANRL-KAGRTQTAYQRLML---------------------LRASLQQKQLY----EERNNNIV 146
            ...::| .|.||...|..::|                     |.|..::...|    |..::.|:
 Worm   893 TSKSQLHTAVRTIFTYFLVLLEHISTHTTLLLPAANVIATWILHADTEELLSYLEHLEPLSSTII 957

  Fly   147 AKI-----NEEVIEKQPEACNITNPSAF------------------DGSTASDMEVEPMEWQESI 188
            :..     |.|...:.||  |:|.|.|.                  ..||.....||.::.....
 Worm   958 SSFSNFPPNLESEAENPE--NVTTPEAILLASFFKIYEPNPTPVRCSRSTNISQAVEKLKILGFS 1020

  Fly   189 EEEAAQNDQDEAKKGDDTLLMLPAESIEEEAPQKGQ--DEAKEEDDTILMLQAADAEELPPRLED 251
            .|::.::.::..:|..|.|         ||...:.|  ||.:....|.:::...
 Worm  1021 AEKSEKSGENGKQKLGDGL---------EEPKSREQMIDEQRGLGKTTIVIHPE----------- 1065

  Fly   252 YMYFVLDTNVLIHNHKFVERLTD---------VVLPGTVGSMLYLPYIVIKELDKLKSKYQSDC- 306
              |.:.||||||.:.:.::.|.:         :::|.||  :..|.||.  :|..|.||..|:.
 Worm  1066 --YLIPDTNVLIGDLQLMKNLLETAQKNKKFQILVPTTV--LDELQYIA--KLSPLDSKSNSEAH 1124

  Fly   307 -LQRVI-AMRAIRFLNTKFDESFQIQAQSALEEADHLI----------------------KIDCP 347
             .:|:. |..|:.:|.           :.|.::..||.                      ::...
 Worm  1125 DPERISKAKIAVAWLK-----------EQAKQKTGHLYTLTTTGKRLPTLSIVSEDLEGHEMTTN 1178

  Fly   348 DDSILNCCLQLQAQVP------------HMILLTNDANLRLKANASNIQVSCR 388
            ||.|||..|:....:|            ..:|:|.|..|.:||..:|.  .||
 Worm  1179 DDMILNSALRWSESLPGSTAPSATEISQKCVLITGDRGLTIKAIGNNF--PCR 1229

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7206	NP_996499.1	PIN_Smg5-Smg6-like	254..392	CDD:189050	42/181 (23%)
smg-6	NP_497566.3	EST1	541..661	CDD:371012
		EST1_DNA_bind	669..995	CDD:371011	50/298 (17%)
		PIN_Smg6-like	1060..1237	CDD:350233	42/200 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1427
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030