DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ada3 and tada3

DIOPT Version :9

Sequence 1:	NP_001259667.1	Gene:	Ada3 / 32787	FlyBaseID:	FBgn0030891	Length:	588	Species:	Drosophila melanogaster
Sequence 2:	XP_012816385.1	Gene:	tada3 / 493402	XenbaseID:	XB-GENE-969840	Length:	433	Species:	Xenopus tropicalis

Alignment Length:	496	Identity:	142/496 - (28%)
Similarity:	231/496 - (46%)	Gaps:	112/496 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 DVPKLLPTIAAALQRPADDHLAAEDLDAVQLELEQMLSNVALRTRVLKAEYDSL-DKDEKRQDRR 134
            |..||.|...|.|.|..||.:..|:||.:|||||.:||:.:.|.|||:||...| |..:|:.|||
Frog    18 DHVKLCPRYTAVLSRSEDDGIGIEELDTLQLELETLLSSASRRLRVLEAETQILTDWQDKKGDRR 82

  Fly   135 KLDRVPGSPPCPASMLNGLLGIGSNSSTSLGSPLGGGGASSSSQSKRKRDEPTGVRKKHSSMTIL 199
                              .|.:|...  .||:|:        ..||.|:.:..| :..|:|
Frog    83 ------------------FLKLGKEH--ELGTPI--------KHSKPKKQKLDG-KGSHAS---- 114

  Fly   200 KQQGVSGGTSKHQAKNSPLVVH--TDDSMDYLPTLAAANASGSVLPHHQPLPQLPKMTVPKNDTP 262
               |...|..|.:.....:..:  |||.:|                       :|:  :||||.|
Frog   115 ---GPGPGRPKSRNMQQKMQEYEFTDDPVD-----------------------VPR--IPKNDAP 151

  Fly   263 NKFWLSVEPYCMPLTNEDLRLIDDLLE------QYWGPLVPPVPPLGPHYSTVWAQEDIKALQPG 321
            |:||.||||||..:||:::::::|||:      .|:     .:||||.|||..|||||:...|..
Frog   152 NRFWASVEPYCADITNDEIKVLEDLLKTPEDEADYY-----KIPPLGKHYSQRWAQEDLLEEQKD 211

  Fly   322 GARI------------------KSNNSSGMLKKAEGMVDESIT----GPLTQRLVSALMEESLMT 364
            |||.                  ...|...:|||:|...|:...    |.|||||:.||:||::::
Frog   212 GARTALSGDKKKGILGPLAELDSKGNVDSLLKKSESQHDQPEDGCPFGHLTQRLLQALVEENIIS 276

  Fly   365 LPSEQAAVGEHSNSTTSSSNENTHSHSSSSANAAAAAASGNFRSLAMMKHGVGIEQRLKKTLIEN 429
             |.|.:.:.|.|...:.:...:|...|.:...:|              .|...:|.|:|:.||..
Frog   277 -PVEDSPIPEISGKESGTDGASTSPRSQNKPFSA--------------PHTKSLEVRIKEELIAQ 326

  Fly   430 GLIDASEFAAHEDVDEVLMEIKRVTTEISTISQFNSEELKRLRAVASEEIKRIAIKQKLDMVDQE 494
            ||:::.:..|.:..||||.|:::...|:..:|..|..:.:.|..:|.||:.|..::|::.|.|.|
Frog   327 GLLESDDRPAEDSEDEVLAELRKRQAELKALSAHNRAKKQELLRLAKEEMNRQELRQRVRMADNE 391

  Fly   495 ILECYKRMLQYRAKRKGHTIEEKQEILRLTNEQRLLADQLE 535
            :::.:::::..|.|::..|.:||.:..:...|:..:...|:
Frog   392 VMDAFRKIMAARQKKRTPTKKEKDQAWKALKERESILKLLD 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ada3	NP_001259667.1	Ada3	413..518	CDD:287205	30/104 (29%)
tada3	XP_012816385.1	Ada3	310..432	CDD:287205	32/121 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	128	1.000	Domainoid score	I5264
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4633
Inparanoid	1	1.050	185	1.000	Inparanoid score	I3819
OMA	1	1.010	-	-		QHG48706
OrthoDB	1	1.010	-	-		D1026409at2759
OrthoFinder	1	1.000	-	-		FOG0006498
OrthoInspector	1	1.000	-	-		oto102453
Panther	1	1.100	-	-	LDO	PTHR13556
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R809
SonicParanoid	1	1.000	-	-		X6237
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110