Protein Alignment Ada3 and TADA3

DIOPT Version :10

• Sequence 1: NP_001259667.1
• Gene: Ada3 / 32787
• FlyBaseID: FBgn0030891
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_006345.1
• Gene: TADA3 / 10474
• HGNCID: 19422
• Length: 432
• Species: Homo sapiens
• Alignment Length: 501
• Identity: 137/501 - (27%)
• Similarity: 225/501 - (44%)
• Gaps: 129/501 - (25%)

  Fly    74 KLLPTIAAALQRPADDHLAAEDLDAVQLELEQMLSNVALRTRVLKAEYDSL-DKDEKRQDRRKLD 137
            |:.|...|.|.|..||.:..|:||.:|||||.:||:.:.|.|||:||...| |..:|:.|||.|
Human    21 KVCPRYTAVLARSEDDGIGIEELDTLQLELETLLSSASRRLRVLEAETQILTDWQDKKGDRRFL- 84

  Fly   138 RVPGSPPCPASMLNGLLGIGSNSSTSLGSPLGGGGASSSSQSKRKRDEPTGVRKKHSSMTILKQQ 202
                                                      |..||...|...||......|.:
Human    85 ------------------------------------------KLGRDHELGAPPKHGKPKKQKLE 107

  Fly   203 GVSG-----GTSKHQAKN-SPLVVH---TDDSMDYLPTLAAANASGSVLPHHQPLPQLPKMTVPK 258
            |.:|     |..:.::|| .|.:..   |||.:|                       :|:  :||
Human   108 GKAGHGPGPGPGRPKSKNLQPKIQEYEFTDDPID-----------------------VPR--IPK 147

  Fly   259 NDTPNKFWLSVEPYCMPLTNEDLRLIDDLLEQYWGPLVPP--------VPPLGPHYSTVWAQEDI 315
            ||.||:||.||||||..:|:|::|.:::||:       ||        :||||.|||..|||||:
Human   148 NDAPNRFWASVEPYCADITSEEVRTLEELLK-------PPEDEAEHYKIPPLGKHYSQRWAQEDL 205

  Fly   316 KALQPGGAR-----------------IKSNNSSGMLKKAEGM----VDESITGPLTQRLVSALME 359
            ...|..|||                 :.:.:...:|||:|..    .|....|.|||||:.||:|
Human   206 LEEQKDGARAAAVADKKKGLMGPLTELDTKDVDALLKKSEAQHEQPEDGCPFGALTQRLLQALVE 270

  Fly   360 ESLMTLPSEQAAVGEHSNSTTSSSNENTHSHSSSSANAAAAAASGNFRSLAMMKHGVGIEQRLKK 424
            |:::: |.|.:.:.:.|...:.:...:|...:.:...:              :.|...:|.|:|:
Human   271 ENIIS-PMEDSPIPDMSGKESGADGASTSPRNQNKPFS--------------VPHTKSLESRIKE 320

  Fly   425 TLIENGLIDASEFAAHEDVDEVLMEIKRVTTEISTISQFNSEELKRLRAVASEEIKRIAIKQKLD 489
            .||..||:::.:..|.:..||||.|:::...|:..:|..|..:...|..:|.||:.|..::|::.
Human   321 ELIAQGLLESEDRPAEDSEDEVLAELRKRQAELKALSAHNRTKKHDLLRLAKEEVSRQELRQRVR 385

  Fly   490 MVDQEILECYKRMLQYRAKRKGHTIEEKQEILRLTNEQRLLADQLE 535
            |.|.|:::.:::::..|.|::..|.:||.:..:...|:..:...|:
Human   386 MADNEVMDAFRKIMAARQKKRTPTKKEKDQAWKTLKERESILKLLD 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ada3	NP_001259667.1	Ada3	413..512	CDD:462993	28/98 (29%)
TADA3	NP_006345.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	87..126		10/38 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	272..319		7/61 (11%)
		Ada3	309..422	CDD:462993	31/112 (28%)