DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7536 and ERD1

DIOPT Version :9

Sequence 1:	NP_001285398.1	Gene:	CG7536 / 32786	FlyBaseID:	FBgn0030890	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	NP_010702.4	Gene:	ERD1 / 852023	SGDID:	S000002822	Length:	362	Species:	Saccharomyces cerevisiae

Alignment Length:	363	Identity:	94/363 - (25%)
Similarity:	150/363 - (41%)	Gaps:	68/363 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   270 FIFLIGVNIYGW---------RSSGVNHVLIFEL--DPRNHLSEQHLMELAAIFGVIWTLSMLSF 323
            ||.||.:.::.|         .:..|:.|::..:  |.|...:.|.|...|..|.:..|..::.|
Yeast    25 FIVLIILALWIWTWILKFFLHSNLDVSQVILTRVPHDIRPGYTLQQLHRTARNFALKITRIIIPF 89

  Fly   324 LYSASLAIPAFIN----PLTLTLIMVLFLANPFHVLYHDARFW--------LWRITGRCV---SA 373
             :.|::.:..|:|    ||...:::|.||.    ::.....||        :...|.||:   |:
Yeast    90 -HFATVFLFEFMNIIEGPLKNIILIVYFLP----LIQCVTIFWFLLKECQIIKYCTRRCLLIESS 149

  Fly   374 PFFHVGFADFWLGDQLNSLATAILDFEYLICFYFTNGNWTEARDASICMEKDFIIRPIVNCLPAW 438
            | ..:......:.|.|.|.|..::||.......|.. .:|.. |.|:.:            ||..
Yeast   150 P-RSLRNTYILISDTLTSFAKPLIDFTLFTSLIFRE-PFTHF-DLSVAL------------LPVL 199

  Fly   439 FRFAQCLRRYRDSREAFPHLVNAGKYSTTFMVVIFATLKSFHSPNYASTFDNP---YTWLWIIAS 500
            .|..||||.||...|| ..|.||.|||.. :.::|.|   :.|..|..:.:..   :...|.:
Yeast   200 VRLLQCLREYRLLHEA-TLLFNALKYSCN-LPILFCT---WRSRVYEGSINEERLHHVQRWFM-- 257

  Fly   501 IVSSCYAYTWDIKMDWGLFDKNAGENTFLR---EEVVYSSTGFYYFAILEDLALRFIWALSFYLT 562
            :::|.|...||::|||.|     ...|.||   :..|......|:.|||.|..|||.|...:...
Yeast   258 LINSSYTLFWDVRMDWSL-----DSLTSLRSRSKSAVTLKKKMYHSAILVDFLLRFWWLWVYLSQ 317

  Fly   563 EMKIVSSD----IMTSVTGILEVFRRFVWNFFRLENEH 596
            .:|:|::|    .........||.||.:|..|:|:.|:
Yeast   318 NLKLVAADSDYIFFQGEMQYFEVIRRGIWVVFKLDAEY 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7536	NP_001285398.1	SPX_XPR1_like	2..156	CDD:269898
		SPX	3..158	CDD:281146
		EXS	258..597	CDD:281164	94/363 (26%)
ERD1	NP_010702.4	EXS	1..362	CDD:413852	94/363 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5409
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.569298	Normalized mean entropy	S1995
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000547
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1440
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.790