DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7536 and AT1G35350

DIOPT Version :9

Sequence 1:	NP_001285398.1	Gene:	CG7536 / 32786	FlyBaseID:	FBgn0030890	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	NP_174768.2	Gene:	AT1G35350 / 840424	AraportID:	AT1G35350	Length:	751	Species:	Arabidopsis thaliana

Alignment Length:	773	Identity:	199/773 - (25%)
Similarity:	313/773 - (40%)	Gaps:	196/773 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFAEHLSAHITPEWRKQYINYEEMKAMLYLAVEEAPSVESVEDDVLKRHFA---NFD------- 55
            |||.:...|.:.|||::.|::|..:|.:|..........||  ..||||..:   ||.
plant     1 MKFGKEYVAQMIPEWQQAYMDYTCLKTILREIKTSQKRSES--QGVLKRKLSGRRNFSGLTKRYS 63

  Fly    56 --------EN----------------------------------FFHYCDKELKKINTFYSEKLA 78
                    ||                                  ||...|.|..|:|.||...:.
plant    64 RTFSSRDLENHDIMVHATTGDDGFEKYETTILKVSEVGRESELVFFKTLDLEFDKVNRFYRSNVE 128

  Fly    79 EATRKFATLNAEL---------------------KTSIEESERSAKKSKGH-------------- 108
            |..::...||.::                     ..|::.:...:|:.||.
plant   129 ELVKEAVVLNRQMDALIAYRIKLDQPSTSWSCSETVSVDINALDSKEQKGKTLAEEMGIKVEENV 193

  Fly   109 -------KRHA----ALPDR----------------------------------KARE-LKLAFS 127
                   |..|    ::.||                                  |..| ||..|.
plant   194 SNGGDSTKETAPEALSVLDRIRLNKNQENPLSTIRNVLKLSNKEDIKFTKENLKKIEERLKNVFI 258

  Fly   128 EFYLSLILLQNYQNLNHTGFRKILKKHDKL-LRVDTGAKWRQEYVEASHFFTNKDIDNIINETET 191
            |||..|..|:||..||.....||:||:||: ||  ..||...|.|:.|:..::.:|:.::...|:
plant   259 EFYRKLRHLKNYSFLNTLAISKIMKKYDKIALR--NAAKLYMEMVDKSYLTSSDEINKLMLRVES 321

  Fly   192 TVTGELEGGDRQRAMKRLRVPPLGEQQSPWTTFKVGLFSGSFIVLVIVV--------VVSAIFHE 248
            .......|.:|.:.|..||  |...::....||..|.|.|..:.|||.:        ::.|:.|:
plant   322 IFVEHFAGSNRSKGMNLLR--PKVTKEKHRITFSTGFFVGCTVSLVIALGLFIHARNIMGAVGHK 384

  Fly   249 ISGENLKVTFRLYRGPLLIIEFIFLIGVNIYGWRSSGVNHVLIFELDPRNHLSEQHLMELAAIFG 313
            :..|.:   |.||.....::..:.:...|||.|:...||:..||.......|...|::.|:  ||
plant   385 LYMETM---FPLYSLFAFVVLHMIMYASNIYFWKRYRVNYPFIFGFKEGTELGYGHVLLLS--FG 444

  Fly   314 VIWTLSMLSFLYSASLAIPAFIN---------PLTLTLIMVLFLANPFHVLYHDARFWLWRITGR 369
             :.||::.:.|.:..:.:....|         ||.:..:::.....||::.|..:||:...:..|
plant   445 -LGTLALCAVLVNMDMEMDPNTNDYKTITELVPLFVVALVIAISVCPFNIFYRSSRFFFLMVLFR 508

  Fly   370 CVSAPFFHVGFADFWLGDQLNSLATAILDFEYLICFYFTNGNWTEARD-ASICMEKD----FIIR 429
            |::||.:.|...||:|.|||.|...|:...|:.||:|    .|.:.:. .|.|...|    |..
plant   509 CIAAPLYKVNLPDFFLADQLTSQVQALRSLEFYICYY----GWGDFKQRQSTCKSSDVYSTFYF- 568

  Fly   430 PIVNCLPAWFRFAQCLRRY---RDSREAFPHLVNAGKYSTTFMVVIFATLKSFHSPNYASTFDNP 491
             ||..:|.|.||.||:||.   :|..:.|    ||.||..|.:.|...|..|.:..|
plant   569 -IVAVIPYWSRFLQCVRRLIEEKDVSQGF----NALKYLLTIVAVCLRTAFSINRGN-------- 620

  Fly   492 YTW---LWIIASIVSSCYAYTWDIKMDWGLFDKNAGENTFLREEVVYSSTGFYYFAILEDLALRF 553
             .|   .|:.:.: ::.|...|||..||||..:.:  .::|||:::......||.|::.::.||.
plant   621 -DWKIAAWVFSGL-ATFYGTYWDIVYDWGLLHRPS--KSWLREKLLVPHKSVYYVAMVVNVVLRL 681

  Fly   554 IWALSFYLTEMKIVSSDIMTSVTGILEVFRRFVWNFFRLENEHLNNCGKFRAVRDISI 611
            .|..:.....:..:..:.|.::..|||:.||.:|||||||||||||.|||||.:.:.:
plant   682 AWLQTVLDFNISFLHRETMVALIAILEIIRRGIWNFFRLENEHLNNVGKFRAFKSVPL 739

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7536	NP_001285398.1	SPX_XPR1_like	2..156	CDD:269898	57/286 (20%)
		SPX	3..158	CDD:281146	58/288 (20%)
		EXS	258..597	CDD:281164	104/358 (29%)
AT1G35350	NP_174768.2	SPX_PHO1_like	2..295	CDD:269897	61/296 (21%)
		SPX	3..300	CDD:281146	62/300 (21%)
		EXS	391..725	CDD:281164	104/358 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	174	1.000	Domainoid score	I1107
eggNOG	1	0.900	-	-		E1_COG5409
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	292	1.000	Inparanoid score	I823
OMA	1	1.010	-	-		QHG54286
OrthoDB	1	1.010	-	-		D536327at2759
OrthoFinder	1	1.000	-	-		FOG0000547
OrthoInspector	1	1.000	-	-		mtm1032
orthoMCL	1	0.900	-	-		OOG6_100965
Panther	1	1.100	-	-	O	PTHR10783
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X439
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.840