DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7536 and AT1G26730

DIOPT Version :9

Sequence 1:	NP_001285398.1	Gene:	CG7536 / 32786	FlyBaseID:	FBgn0030890	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	NP_173995.1	Gene:	AT1G26730 / 839214	AraportID:	AT1G26730	Length:	750	Species:	Arabidopsis thaliana

Alignment Length:	778	Identity:	193/778 - (24%)
Similarity:	316/778 - (40%)	Gaps:	192/778 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFAEHLSAHITPEWRKQYINYEEMKAMLY----------------------------------L 31
            |||.:.....:.|||::.|::|..:|::|.                                  .
plant     1 MKFGKDFVRQMIPEWQQAYMDYAGLKSILQEIQTSRKRSERPGILKRKLSGSRNFSGLTKRYSRT 65

  Fly    32 AVEEAPSVESV------EDDVLKRHFANFDE----------NFFHYCDKELKKINTFYSEKLAEA 80
            |....|.::.:      .||..:|:.....|          .||...|.|..|:|.||..|:.|.
plant    66 ASTREPEIQDILVHATTGDDGFERYETTILEVAEAGRESELAFFKTLDLEFDKVNHFYRSKVEEM 130

  Fly    81 TRKFATLNAEL------KTSIEESERSAKKSK--------------------------------- 106
            .::...||.::      :..:|....|...|:
plant   131 VKEAVVLNKQMDALIAFRIKVERPSSSWSCSETVSVDMNALDSNDQRNTLAEEMGIRVEGNGSNG 195

  Fly   107 GHKRHAALPD----------------------------------------RKARE-LKLAFSEFY 130
            |.....::|.                                        :|..| ||..|.|||
plant   196 GDSTKESVPQVLSVLERIRLNKTQETPLSTIKNVLKLSNQEELKFTRENLKKIEERLKNVFIEFY 260

  Fly   131 LSLILLQNYQNLNHTGFRKILKKHDKLLRVDTGAKWRQEYVEASHFFTNKDIDNIINETETTVTG 195
            ..|..|:||..||.....||:||:||:.. .:.||...|.|:.|:..::.:|:.::...|:|...
plant   261 RKLRHLKNYSFLNTLAISKIMKKYDKIAS-RSAAKPYMEMVDKSYLTSSDEINKLMLRVESTFVE 324

  Fly   196 ELEGGDRQRAMKRLRVPPLGEQQSPWTTFKVGLFSGSFIVLVIVVV--------VSAIFHEISGE 252
            ...|.:|.:.|..||  |..:::....||..|.|.|..:.||:.:|        :.|:.|::..|
plant   325 HFAGLNRSKGMNLLR--PKVKKEKHRITFSTGFFVGCTVSLVVALVMFIHARNIMGAVGHKVYME 387

  Fly   253 NLKVTFRLYRGPLLIIEFIFLIGVNIYGWRSSGVNHVLIFELDPRNHLSEQHLMELAAIFGVIWT 317
            .:   |.||.....::..:.:...|||.|:...||:..||.......|..:|::.|:  || :.|
plant   388 TM---FPLYSLFAFVVLHMIMYASNIYFWKRYRVNYPFIFGFKEGTELGYRHVLLLS--FG-LGT 446

  Fly   318 LSMLSFLYSASLAIPAFIN---------PLTLTLIMVLFLANPFHVLYHDARFWLWRITGRCVSA 373
            |::.:.|.:..:.:....|         |:.:..::|..|..||::.|..:|.:...:..||::|
plant   447 LALCAVLINLDMEMDPNTNDYKTMTELLPMFILALVVAILFCPFNIFYRSSRVFFLMVVFRCIAA 511

  Fly   374 PFFHVGFADFWLGDQLNSLATAILDFEYLICFYFTNGNWTEARD-ASICMEKD----FIIRPIVN 433
            |.:.|...||:|.|||.|...|:...|:.||:|    .|.:.:. .:.|...|    |..  ||.
plant   512 PLYKVNLPDFFLADQLTSQVQALRSLEFYICYY----GWGDFKHRQNTCRSSDVYSTFYF--IVA 570

  Fly   434 CLPAWFRFAQCLRRY---RDSREAFPHLVNAGKYSTTFMVVIFATLKSFHSPNYASTFDNPYTWL 495
            .:|.|.||.||:||.   .||.:.:    ||.||..|.:.|...|..||:..|           :
plant   571 VIPYWSRFLQCVRRLIEENDSSQGY----NALKYLLTVVAVCLRTAYSFNRGN-----------I 620

  Fly   496 WIIA----SIVSSCYAYTWDIKMDWGLFDKNAGENTFLREEVVYSSTGFYYFAILEDLALRFIWA 556
            |.|:    |.:::.|...|||..||||..:.:  ...|||:::......||.||:.::.||..|.
plant   621 WKISAWVFSALATFYGTYWDIVFDWGLLHRPS--KHLLREKLLVPHKAVYYVAIVLNIVLRMAWL 683

  Fly   557 LSFYLTEMKIVSSDIMTSVTGILEVFRRFVWNFFRLENEHLNNCGKFRAVRDISIAPLDSSDQ 619
            .:.....:..:..:.|.::...||:.||.:|||||||||||||.|||||.:.:.: |.:.:::
plant   684 QTVLDFNLSFLHRETMIALLAALEIIRRGIWNFFRLENEHLNNVGKFRAFKSVPL-PFNYNEE 745

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7536	NP_001285398.1	SPX_XPR1_like	2..156	CDD:269898	50/283 (18%)
		SPX	3..158	CDD:281146	51/284 (18%)
		EXS	258..597	CDD:281164	105/359 (29%)
AT1G26730	NP_173995.1	SPX_PHO1_like	2..294	CDD:269897	52/292 (18%)
		SPX	3..299	CDD:281146	53/296 (18%)
		SPX	<212..286	CDD:271919	18/73 (25%)
		EXS	390..724	CDD:281164	105/359 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	174	1.000	Domainoid score	I1107
eggNOG	1	0.900	-	-		E1_COG5409
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	292	1.000	Inparanoid score	I823
OMA	1	1.010	-	-		QHG54286
OrthoDB	1	1.010	-	-		D536327at2759
OrthoFinder	1	1.000	-	-		FOG0000547
OrthoInspector	1	1.000	-	-		mtm1032
orthoMCL	1	0.900	-	-		OOG6_100965
Panther	1	1.100	-	-	O	PTHR10783
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X439
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.840