DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7536 and AT3G29060

DIOPT Version :9

Sequence 1:	NP_001285398.1	Gene:	CG7536 / 32786	FlyBaseID:	FBgn0030890	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	NP_189549.2	Gene:	AT3G29060 / 822550	AraportID:	AT3G29060	Length:	800	Species:	Arabidopsis thaliana

Alignment Length:	815	Identity:	191/815 - (23%)
Similarity:	312/815 - (38%)	Gaps:	230/815 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFAEHLSAHITPEWRKQYINYEEMKAM------------------------------------- 28
            |||.......:..||::.|::|..:|::
plant     1 MKFGREFETQMIQEWKEAYMDYRSLKSIVKQILRYRLQKQQRPPPPPPPPSTGDTVPLKTDGGEG 65

  Fly    29 ----------------LYLA-------VEEAPSVESVEDDVL--KRH------------------ 50
                            ||.|       ...:|.......:.|  |||
plant    66 GGGGGGGGPGLSRRISLYRAFSGLTNRASRSPKKSHKHHNPLSSKRHHHHHNHHHYHLFDDDEEQ 130

  Fly    51 --FANFDE--------------------NFFHYCDKELKKINTFYSEKLA-------EATRKFAT 86
              ..|.||                    .||...|.|..|:..||.:|:.       |.:|:...
plant   131 IILINEDETASYTTTFLNSAEEGGEMEVQFFRRLDGEFNKVLRFYKQKVENVMEEADELSRQLNV 195

  Fly    87 LNAELKTSIEESE--------------------------------RSAKKSKGHK---------- 109
            |.| |:..:|...                                |..:|::..|
plant   196 LIA-LRVKVENPHVHLPPDLNSVASAPSSPHSTMRTPAPSPMDVIREMEKTEDKKVFKPAPVEML 259

  Fly   110 RHAAL--------------------------PD-RKAREL-KLAFSEFYLSLILLQNYQNLNHTG 146
            .|..|                          |: |:|.|| ..||.|||..|..|::|..||...
plant   260 DHVKLKIDPETPLLTLKMMILGLPSEQTFSKPELRRAEELMNRAFVEFYQKLRFLKSYCFLNQLA 324

  Fly   147 FRKILKKHDKLLRVDTGAKWRQEY---VEASHFFTNKDIDNIINETETTVTGELEGGDRQRAMKR 208
            |.|||||:||    .|.....:.|   |:.|:..:..::..:::..|.|.......|:.:..||.
plant   325 FAKILKKYDK----TTSRNASKPYLNTVDHSYLGSCDEVSRLMSRVEATFIKHFANGNHREGMKC 385

  Fly   209 LRVPPLGEQQSPWTTFKVGLFSGSFIVLVIVVVVSAIFHEISG-----------ENLKVTFRLYR 262
            ||  |..:::....|:.:|.|||..:.|.|.:.|  :.| |.|           ||:   |.||.
plant   386 LR--PKTKREKHRITYFLGFFSGCAVALAIAITV--LVH-IRGLTKSEGRHQYMENI---FPLYS 442

  Fly   263 GPLLIIEFIFLIGVNIYGWRSSGVNHVLIFELDPRNHLSEQHLM----ELAAIF--GVIWTLSML 321
            ....:...:|:...:||.|....||:..||..:..|.|..:.::    .||.:.  |||..|.|.
plant   443 LFGFVAVHLFMYAADIYFWSRYRVNYPFIFGFEQGNDLGYREVLLVGSGLAVLTFGGVISNLDME 507

  Fly   322 SFLYSASLAIPAFINPLTLTLIMVLFLANPFHVLYHDARFWLWRITGRCVSAPFFHVGFADFWLG 386
            ....:.|.::...:.||.|.:.:::.|..||:::|..:|::......||:.:|.:.|...||:|.
plant   508 MDPRTKSFSVITELVPLALLVCLMMVLFCPFNIIYRSSRYFFVGSVFRCLLSPLYKVILPDFFLA 572

  Fly   387 DQLNSLATAILDFEYLICFYFTNGNWTEARDASICMEKDFI--IRPIVNCLPAWFRFAQCLRRYR 449
            |||.|.........:.:|:|...|::  .|....|.:.:..  :..:|..:|.||||||.:||..
plant   573 DQLTSQVQTFRSLLFYVCYYGWGGDF--KRRTHTCYDSEIYKELYLVVAIIPYWFRFAQSIRRLV 635

  Fly   450 DSREAFPHLVNAGKYSTTFMVVIFATLKSFHSPNYASTFDNPYTWLW--IIASIVSSCYAYTWDI 512
            :.::.. |.:||.||.:|.:.|...|:.......|         ||.  :..|.:::.:...|||
plant   636 EEKDKM-HGLNALKYLSTILAVAARTIFEMKRGTY---------WLTVAVTTSSIATLFNTYWDI 690

  Fly   513 KMDWGLFDKNAGENTFLREEVVYSSTGFYYFAILEDLALRFIWALSFY-LTEMKIVSSDIMTSVT 576
            ..||||.::|: :|.:||::::......|:..::.::.||..|..:.. :.|...:....:.:|.
plant   691 FRDWGLMNRNS-KNPWLRDKLLVPYKSIYFIVMVANVVLRLAWMQTVLGIKEAPFLHKRALVAVV 754

  Fly   577 GILEVFRRFVWNFFRLENEHLNNCGKFRAVRDISI 611
            ..||:.||.:|||||||||||||.||:||.:.:.:
plant   755 ASLEIVRRGIWNFFRLENEHLNNVGKYRAFKSVPL 789

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7536	NP_001285398.1	SPX_XPR1_like	2..156	CDD:269898	58/332 (17%)
		SPX	3..158	CDD:281146	59/333 (18%)
		EXS	258..597	CDD:281164	97/349 (28%)
AT3G29060	NP_189549.2	COG5408	1..339	CDD:227695	62/342 (18%)
		SPX_PHO1_like	2..342	CDD:269897	61/344 (18%)
		EXS	438..775	CDD:281164	97/349 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	174	1.000	Domainoid score	I1107
eggNOG	1	0.900	-	-		E1_COG5409
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	292	1.000	Inparanoid score	I823
OMA	1	1.010	-	-		QHG54286
OrthoDB	1	1.010	-	-		D536327at2759
OrthoFinder	1	1.000	-	-		FOG0000547
OrthoInspector	1	1.000	-	-		mtm1032
orthoMCL	1	0.900	-	-		OOG6_100965
Panther	1	1.100	-	-	O	PTHR10783
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X439
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.840