DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7536 and PHO1

DIOPT Version :9

Sequence 1:	NP_001285398.1	Gene:	CG7536 / 32786	FlyBaseID:	FBgn0030890	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	NP_188985.2	Gene:	PHO1 / 821924	AraportID:	AT3G23430	Length:	782	Species:	Arabidopsis thaliana

Alignment Length:	803	Identity:	206/803 - (25%)
Similarity:	328/803 - (40%)	Gaps:	215/803 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFAEHLSAHITPEWRKQYINYEEMKAML------------------------------------ 29
            :||::.|.|.:.|||::.::||..:|..:
plant     2 VKFSKELEAQLIPEWKEAFVNYCLLKKQIKKIKTSRKPKPASHYPIGHHSDFGRSLFDPVRKLAR 66

  Fly    30 -----YLAVEEAPSVESVE---------DDV-------LKRHFANFDE--NFFHYCDKELKKINT 71
                 ..:..|.|.:..|.         |||       |.:.|:..||  .||...|:||.|:|.
plant    67 TFSDKLFSNSEKPEILQVRRRRGSSETGDDVDEIYQTELVQLFSEEDEVKVFFARLDEELNKVNQ 131

  Fly    72 FYSEKLAEATRKFATLNAELKT---------------------------SIEESERSA------- 102
            |:..|..|...:...|..:|:|                           |:..|:.||
plant   132 FHKPKETEFLERGEILKKQLETLAELKQILSDRKKRNLSGSNSHRSFSSSVRNSDFSAGSPGELS 196

  Fly   103 -----------------------------KKSKGHKRHAAL----PDRKA--------------- 119
                                         .|:||.|...:|    ||..|
plant   197 EIQSETSRTDEIIEALERNGVSFINSATRSKTKGGKPKMSLRVDIPDAVAGAEGGIARSIATAMS 261

  Fly   120 ------------------------RELKLAFSEFYLSLILLQNYQNLNHTGFRKILKKHDKLLRV 160
                                    ::::.||.|.|..|.||:.|.:||...|.||:||.||:...
plant   262 VLWEELVNNPRSDFTNWKNIQSAEKKIRSAFVELYRGLGLLKTYSSLNMIAFTKIMKKFDKVAGQ 326

  Fly   161 DTGAKWRQEYVEASHFFTNKDIDNIINETETTVTGELEGGDRQRAMKRLRVPPLGEQQSPWTTFK 225
            :..:.: .:.|:.|.|.::..:..:::|.|:..|......||::|||.|:  |...:.|...||.
plant   327 NASSTY-LKVVKRSQFISSDKVVRLMDEVESIFTKHFANNDRKKAMKFLK--PHQTKDSHMVTFF 388

  Fly   226 VGLFSGSFIVLVIVVVVSAIFHEISG--------ENLKVTFRLYRGPLLIIEFIFLIGVNIYGWR 282
            ||||:|.||.|.::.::.|   .:||        ..|:..:.::....|:...:|:.|.|:|.|:
plant   389 VGLFTGCFISLFVIYIILA---HLSGIFTSSDQVSYLETVYPVFSVFALLSLHMFMYGCNLYMWK 450

  Fly   283 SSGVNHVLIFELDPRNHLSEQHLMELAAIFGVIWTLSMLSFL------YSASL--AIPAFINPLT 339
            ::.:|:..|||..|...|..:....:...|......:|:..|      :|||.  .||..
plant   451 NTRINYTFIFEFAPNTALRYRDAFLMGTTFMTSVVAAMVIHLILRASGFSASQVDTIPGI----- 510

  Fly   340 LTLIMVLFLANPFHVLYHDARFWLWRITGRCVSAPFFHVGFADFWLGDQLNSLATAILDFEYLIC 404
            |.||.:..|..||:..|...||...||..:.|.:||:.|...||::||||.|....:...|...|
plant   511 LLLIFICVLICPFNTFYRPTRFCFIRILRKIVCSPFYKVLMVDFFMGDQLTSQIPLLRHLETTGC 575

  Fly   405 FY----FTNGNWTEARDASICMEKDFIIRPIVNCLPAWFRFAQCLRRYRDSREAFP-HLVNAGKY 464
            ::    |....:...::.....|..::|    :.||.::|..||:||:.|  |:.| ||:|.|||
plant   576 YFLAQSFKTHEYNTCKNGRYYREFAYLI----SFLPYFWRAMQCVRRWWD--ESNPDHLINMGKY 634

  Fly   465 STTFMVVIFATLKSFHSPNYASTFDNPYTWLW--IIASIVSSCYAYTWDIKMDWGLFDKNAGENT 527
             .:.||.....:      .||.  :|...||.  :::|:|::.|...||...||||.:..: :|.
plant   635 -VSAMVAAGVRI------TYAR--ENNDLWLTMVLVSSVVATIYQLYWDFVKDWGLLNPKS-KNP 689

  Fly   528 FLREEVVYSSTGFYYFAILEDLALRFIWALSFYLTEMKIVSSDIMTSVTGILEVFRRFVWNFFRL 592
            :||:.:|..:..|||.:|..:|.||..|..:.....:..|.|.::......|||.||..|||:|:
plant   690 WLRDNLVLRNKNFYYLSIALNLVLRVAWIETIMRFRVSPVQSHLLDFFLASLEVIRRGHWNFYRV 754

  Fly   593 ENEHLNNCGKFRAVRDISIAPLD 615
            |||||||.|:||||:.:.:..||
plant   755 ENEHLNNVGQFRAVKTVPLPFLD 777

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7536	NP_001285398.1	SPX_XPR1_like	2..156	CDD:269898	60/318 (19%)
		SPX	3..158	CDD:281146	61/319 (19%)
		EXS	258..597	CDD:281164	105/353 (30%)
PHO1	NP_188985.2	SPX	2..336	CDD:397293	62/334 (19%)
PHO1	NP_188985.2	EXS	425..759	CDD:397303	105/354 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	174	1.000	Domainoid score	I1107
eggNOG	1	0.900	-	-		E1_COG5409
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H129026
Inparanoid	1	1.050	292	1.000	Inparanoid score	I823
OMA	1	1.010	-	-		QHG54286
OrthoDB	1	1.010	-	-		D536327at2759
OrthoFinder	1	1.000	-	-		FOG0000547
OrthoInspector	1	1.000	-	-		mtm1032
orthoMCL	1	0.900	-	-		OOG6_100965
Panther	1	1.100	-	-	O	PTHR10783
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X439
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840