DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7536 and AT2G03240

DIOPT Version :9

Sequence 1:	NP_001285398.1	Gene:	CG7536 / 32786	FlyBaseID:	FBgn0030890	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	NP_178423.5	Gene:	AT2G03240 / 814853	AraportID:	AT2G03240	Length:	823	Species:	Arabidopsis thaliana

Alignment Length:	839	Identity:	192/839 - (22%)
Similarity:	305/839 - (36%)	Gaps:	256/839 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFAEHLSAHITPEWRKQYINYEEMKAMLYLAVE-------EAP-------------------SV 39
            |||.:..|:.:.|||.:.|::|:.:|:.|...::       ..|                   .:
plant     1 MKFGKEFSSQMVPEWHEAYMDYDYLKSQLKEIIKFKRKTNPHGPHHHHHHLLHRKMTLHRAFSGL 65

  Fly    40 ESVEDDVLKR--------------HFANFDEN--------------------------------- 57
            .|......|.              ||::.|::
plant    66 ISTSPKKKKHHGHGGGHGGGHQIGHFSDSDDDIEEGIKHVTAPILINSASHGYETTFLMASEEGG 130

  Fly    58 -----FFHYCDKELKKINTFYSEKLAEATRKFATLNAEL-------------------------- 91
                 ||...|.|..|:..||.||:.|..::...|..::
plant   131 EYETVFFRRLDDEFNKVEKFYKEKVEEVMKEAVMLEKQMDALIAFRVKVEHPDGWPWEERTVEMT 195

  Fly    92 --------------------------------------------KTSIEESERSAKKSKGH---- 108
                                                        |:|.||.:..|:|.:.:
plant   196 QLASDVANSAAAVAASTPAGARSMKVGAQAHMEAIQEGGSSKAGKSSDEEDDDDAEKEEDNGVSG 260

  Fly   109 -------KRHAALP------DRK---------------------------ARE--------LKLA 125
                   |..|..|      ||.                           :||        |:.|
plant   261 EVSGDVRKMKAGRPPPIEVLDRVKFNHTKETPRSTIKSVLQASNLTELKFSRENLRKVEAKLRRA 325

  Fly   126 FSEFYLSLILLQNYQNLNHTGFRKILKKHDKLLRVDTGAKWRQEYVEASHFFTNKDIDNIINETE 190
            |.|||..|.||::|..||...|.|||||:||:.. ...:|...:.::.|:..::.::..::...|
plant   326 FVEFYQKLRLLKSYSFLNELAFSKILKKYDKITS-RHASKSYMKMIDNSYLGSSDEVTRLVERVE 389

  Fly   191 TTVTGELEGGDRQRAMKRLRVPPLGEQQSPWTTFKVGLFSGSFIVLVIVVVVSAIFHEISGEN-- 253
            .|........:|.:.|..||  |..:::....||..|...|....||:     |:|..|...|
plant   390 ATFIKHFSNANRSKGMNILR--PKAKRERHRITFSTGFLGGCLFSLVV-----ALFAIIRTRNIL 447

  Fly   254 --------LKVTFRLYRGPLLIIEFIFLIGVNIYGWRSSGVNHVLIFELDPRNHLSEQHLMELAA 310
                    :...|.||.....::..|.:...|||.||...||:..||.......|..:.::.:..
plant   448 QEEGQKQYMNTMFPLYSLFGFVVLHILMYAGNIYYWRRYRVNYSFIFGFKHGTELGYRQVLFVGL 512

  Fly   311 IFGVIWTLSMLSFL----------YSASLAIPAFINPLTLTLIMVLFLANPFHVLYHDARFWLWR 365
            ..||...|.:|:.|          |.|...    :.||.|...|.:.|..||::.|..:||:...
plant   513 SIGVFALLCILANLDMEVDPETKDYQALTE----LLPLFLLTGMFVVLVLPFNIFYRSSRFFFLT 573

  Fly   366 ITGRCVSAPFFHVGFADFWLGDQLNSLATAILDFEYLICFYFTNGNWTEARD-ASICMEKD---- 425
            ....|::||.:.|...||.:||||.|...|:...::.||.|    .|.:.:. .:.|.|.|
plant   574 CLFHCLAAPLYKVTLPDFLVGDQLTSQVQALRSIQFYICHY----GWGDYKHRINTCTESDAYNA 634

  Fly   426 FIIRPIVNCLPAWFRFAQCLRRYRDSREAFPHL-VNAGKYSTTFMVVIFATLKSFHSPNYASTFD 489
            |:.  ||..:|...|..|||||..:.:.  |.. .|..||..|.:.|...|       .|:...|
plant   635 FLF--IVAVIPYVSRLLQCLRRLFEEKN--PEQGYNGLKYFLTIVAVCLRT-------TYSVDED 688

  Fly   490 NPYTW--LWIIASIVSSCYAYTWDIKMDWGLFDKNAGENTFLREEVVYSSTGFYYFAILEDLALR 552
            |.:.|  |..|.|.:::.:...||:..||||.::.: :|.:||::::......|:.|::.::.||
plant   689 NQFIWRILAGIFSAIAAIFCTYWDLVYDWGLLNRTS-KNPWLRDKLLVPQKKVYFIAMILNILLR 752

  Fly   553 FIWALSFYLTEMKIVSSDIMTSVTGILEVFRRFVWNFFRLENEHLNNCGKFRAVRDISI 611
            |.|..:........:....|.:|...||:.||.:|||||||||||||.||:||.:.:.:
plant   753 FAWLQTVLDFNFSFMHRQTMVAVVASLEIIRRGIWNFFRLENEHLNNVGKYRAFKTVPL 811

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7536	NP_001285398.1	SPX_XPR1_like	2..156	CDD:269898	58/353 (16%)
		SPX	3..158	CDD:281146	59/354 (17%)
		EXS	258..597	CDD:281164	104/356 (29%)
AT2G03240	NP_178423.5	SPX	1..370	CDD:397293	62/369 (17%)
AT2G03240	NP_178423.5	EXS	459..797	CDD:397303	104/357 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	174	1.000	Domainoid score	I1107
eggNOG	1	0.900	-	-		E1_COG5409
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	292	1.000	Inparanoid score	I823
OMA	1	1.010	-	-		QHG54286
OrthoDB	1	1.010	-	-		D536327at2759
OrthoFinder	1	1.000	-	-		FOG0000547
OrthoInspector	1	1.000	-	-		mtm1032
orthoMCL	1	0.900	-	-		OOG6_100965
Panther	1	1.100	-	-	LDO	PTHR10783
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X439
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.840