Protein Alignment CG7536 and xpr1

DIOPT Version :10

• Sequence 1: NP_573265.1
• Gene: CG7536 / 32786
• FlyBaseID: FBgn0030890
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_001016753.1
• Gene: xpr1 / 549507
• XenbaseID: XB-GENE-1015946
• Length: 692
• Species: Xenopus tropicalis
• Alignment Length: 693
• Identity: 372/693 - (53%)
• Similarity: 486/693 - (70%)
• Gaps: 32/693 - (4%)

  Fly     1 MKFAEHLSAHITPEWRKQYINYEEMKAMLYLAVEEAPSVESVEDDVLKRHFANFDENFFHYCDKE 65
            ||||||||||||||||||||.||..|.|||.|.::|||:|..::|.:||::|.|:|.||..|:||
 Frog     1 MKFAEHLSAHITPEWRKQYIQYEAFKEMLYAAQDQAPSIEVTDEDTVKRYYAKFEEIFFQTCEKE 65

  Fly    66 LKKINTFYSEKLAEATRKFATLNAELKTSIE-ESERSAKKSKGHKRHAA--------LPDRKARE 121
            |.|||||||||||||.|:.|||..||::|:: :.|.||......:|.|.        :..|..::
 Frog    66 LAKINTFYSEKLAEAQRRSATLQNELQSSLDAQRESSAIPGLRQRRKAVFALTHEERVQHRNIKD 130

  Fly   122 LKLAFSEFYLSLILLQNYQNLNHTGFRKILKKHDKLLRVDTGAKWRQEYVEASHFFTNKDIDNII 186
            ||||||||||||||||||||||.||||||||||||:|....||.||..:||.:.|:|.|.|:.:|
 Frog   131 LKLAFSEFYLSLILLQNYQNLNFTGFRKILKKHDKILETSRGADWRVAHVEVAPFYTCKKINQLI 195

  Fly   187 NETETTVTGELEGGDRQRAMKRLRVPPLG-EQQSP-WTTFKVGLFSGSFIVLVIVVVVSAIFHEI 249
            :||||.||.|||.||||:||||||||||| .|.:| ||||:|||:.|.||||.:.::::. .|.:
 Frog   196 SETETVVTNELESGDRQKAMKRLRVPPLGAAQPAPAWTTFRVGLYCGIFIVLNMAIIMAG-SHYL 259

  Fly   250 SGENLKVTFRLYRGPLLIIEFIFLIGVNIYGWRSSGVNHVLIFELDPRNHLSEQHLMELAAIFGV 314
            .|:::....|:|||..|:|||:||:|:|.||||.:||||||||||:|||:||.|||.|:|...|:
 Frog   260 LGKDVWPMVRIYRGGFLLIEFLFLLGINTYGWRQAGVNHVLIFELNPRNNLSHQHLFEIAGFLGI 324

  Fly   315 IWTLSMLSFLYSASLAIPAFINPLTLTLIMVLFLANPFHVLYHDARFWLWRITGRCVSAPFFHVG 379
            :|..|:.|.::...:.:...:|||.|..:|:|||.||....|:.:||||.::..|..:|||..||
 Frog   325 LWCFSLFSCIFGLWINLQMHLNPLILYGLMLLFLVNPTKTFYYKSRFWLLKLLFRVFTAPFHKVG 389

  Fly   380 FADFWLGDQLNSLATAILDFEYLICFYFTNGNWTEARDA-----SICMEKDFIIRPIVNCLPAWF 439
            ||||||.|||||||..::|.|::||||.....|.::...     |:|....:.:|.:|.|:|||.
 Frog   390 FADFWLADQLNSLAVILMDLEFMICFYSFELKWGDSDGLVNSANSVCNSYSYGVRAVVQCIPAWL 454

  Fly   440 RFAQCLRRYRDSREAFPHLVNAGKYSTTFMVVIFATLKSFHSP-NYASTFDNPYTWLWIIASIVS 503
            ||.||||||||::.|||||||||||||||.:|.||.|.|.|.. |::..  ..:.:||||..::|
 Frog   455 RFIQCLRRYRDTKRAFPHLVNAGKYSTTFFMVTFAALYSTHKERNHSDA--QVFFYLWIIFYLIS 517

  Fly   504 SCYAYTWDIKMDWGLFDKNAGENTFLREEVVYSSTGFYYFAILEDLALRFIWALSFYLTEMKIV- 567
            |||...||:||||||||:|||||||||||:||....:||.||::|:.|||.|.:...:|.:.:.
 Frog   518 SCYTLIWDLKMDWGLFDRNAGENTFLREEIVYPQKAYYYCAIIQDVILRFAWTIQISVTSLNLFT 582

  Fly   568 -SSDIMTSVTGILEVFRRFVWNFFRLENEHLNNCGKFRAVRDISIAPLDSSDQALILRLMDEADG 631
             :.||:::|...|||||||||||||||||||||||:||||||||:|||::.||.|:.::||:.||
 Frog   583 DAGDIISTVLAPLEVFRRFVWNFFRLENEHLNNCGEFRAVRDISVAPLNADDQTLLEQMMDQDDG 647

  Fly   632 VINRYTKANRPKPKKVKDPEKRSL----LQTRGSLPDLRIDMD 670
            |      .||.|.:..|..:..||    |.::..:.|.:|.:|
 Frog   648 V------KNRVKSRIWKRSQSMSLRRPRLSSQSKMKDAKILID 684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7536	NP_573265.1	SPX_XPR1_like	2..156	CDD:269898	100/162 (62%)
		EXS	258..597	CDD:460816	182/346 (53%)
xpr1	NP_001016753.1	SPX_XPR1_like	2..165	CDD:269898	100/162 (62%)
		Important for inositol polyphosphate binding. /evidence=ECO:0000250|UniProtKB:P43585	158..165		6/6 (100%)
		EXS	267..613	CDD:460816	182/347 (52%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	660..692		6/25 (24%)