Protein Alignment CG7536 and Xpr1

DIOPT Version :10

• Sequence 1: NP_573265.1
• Gene: CG7536 / 32786
• FlyBaseID: FBgn0030890
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_001099462.1
• Gene: Xpr1 / 289424
• RGDID: 1306554
• Length: 696
• Species: Rattus norvegicus
• Alignment Length: 696
• Identity: 384/696 - (55%)
• Similarity: 477/696 - (68%)
• Gaps: 32/696 - (4%)

  Fly     1 MKFAEHLSAHITPEWRKQYINYEEMKAMLYLAVEEAPSVESVEDDVLKRHFANFDENFFHYCDKE 65
            ||||||||||||||||||||.||..|.|||.|.::|||||..::|.:||:||.|:|.||..|:||
  Rat     1 MKFAEHLSAHITPEWRKQYIQYEAFKDMLYSAQDQAPSVEVTDEDTVKRYFAKFEEKFFQTCEKE 65

  Fly    66 LKKINTFYSEKLAEATRKFATLNAELKTSIEESE--------RSAKKSKGHKRH-AALPDRKARE 121
            |.|||||||||||||.|:||||..||::|::..:        |..:|...|..| ..:..|..::
  Rat    66 LAKINTFYSEKLAEAQRRFATLQNELQSSLDAQKESTGVTTLRQRRKPVFHLSHEERVQHRNIKD 130

  Fly   122 LKLAFSEFYLSLILLQNYQNLNHTGFRKILKKHDKLLRVDTGAKWRQEYVEASHFFTNKDIDNII 186
            ||||||||||||||||||||||.||||||||||||:|....||.||..:||.:.|:..|.|:.:|
  Rat   131 LKLAFSEFYLSLILLQNYQNLNFTGFRKILKKHDKILETSRGADWRVAHVEVAPFYICKKINQLI 195

  Fly   187 NETETTVTGELEGGDRQRAMKRLRVPPLG-EQQSP-WTTFKVGLFSGSFIVLVIVVVVSAIFHEI 249
            :|||..||.|||.||||:||||||||||| .|.:| ||||:||||.|.||||.|.:|.:|:|...
  Rat   196 SETEAVVTNELEDGDRQKAMKRLRVPPLGAAQPAPAWTTFRVGLFFGIFIVLNITLVFAAVFKLE 260

  Fly   250 SGENLKVTFRLYRGPLLIIEFIFLIGVNIYGWRSSGVNHVLIFELDPRNHLSEQHLMELAAIFGV 314
            :...:....|:|||..|:|||:||:|:|.||||.:||||||||||:|||:||.|||.|:|...|:
  Rat   261 TDRTVWPLIRIYRGGFLLIEFLFLLGINTYGWRQAGVNHVLIFELNPRNNLSHQHLFEIAGFLGI 325

  Fly   315 IWTLSMLSFLYSASLAIPAFINPLTLTLIMVLFLANPFHVLYHDARFWLWRITGRCVSAPFFHVG 379
            :|.||:|:..::....||.::.||.|...||.||.||....|:.:||||.::..|..:|||..||
  Rat   326 LWCLSLLACFFAPISIIPIYVYPLALYGFMVFFLINPTKTFYYKSRFWLLKLLFRVFTAPFHKVG 390

  Fly   380 FADFWLGDQLNSLATAILDFEYLICFYFTNGNWTEAR--------DASICMEKDFIIRPIVNCLP 436
            ||||||.||||||:..::|.||:||||.....|.|::        :...|....:.:|.||.|:|
  Rat   391 FADFWLADQLNSLSVILMDLEYMICFYSFELKWDESKGLLPNDPQEPEFCHGYTYGVRAIVQCIP 455

  Fly   437 AWFRFAQCLRRYRDSREAFPHLVNAGKYSTTFMVVIFATLKSFHSP-NYASTFDNPYTWLWIIAS 500
            ||.||.||||||||:|.|||||||||||||||..|.||.|.|.|.. .::.|.  .:.:||::..
  Rat   456 AWLRFIQCLRRYRDTRRAFPHLVNAGKYSTTFFTVTFAALYSTHKERGHSDTM--VFFYLWVVFC 518

  Fly   501 IVSSCYAYTWDIKMDWGLFDKNAGENTFLREEVVYSSTGFYYFAILEDLALRFIWA--LSFYLTE 563
            |:||||...||:||||||||||||||||||||:||....:||.||:||:.|||.|.  :|...|.
  Rat   519 IISSCYTLIWDLKMDWGLFDKNAGENTFLREEIVYPQKAYYYCAIVEDVILRFAWTIQISITATT 583

  Fly   564 MKIVSSDIMTSVTGILEVFRRFVWNFFRLENEHLNNCGKFRAVRDISIAPLDSSDQALILRLMDE 628
            .|....||:.:|...|||||||||||||||||||||||:||||||||:|||::.||.|:.::||:
  Rat   584 FKPHVGDIIATVFAPLEVFRRFVWNFFRLENEHLNNCGEFRAVRDISVAPLNADDQTLLEQMMDQ 648

  Fly   629 ADGVINRYTKANRPKPKKVKDPEKRSLLQTRGSLPDLRIDMDSKKL 674
            .|||      .||.|.:..|..:..||.:.|  ||......|:|.|
  Rat   649 EDGV------RNRQKSRSWKYNQSISLRRPR--LPSQSKARDTKVL 686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7536	NP_573265.1	SPX_XPR1_like	2..156	CDD:269898	102/162 (63%)
		EXS	258..597	CDD:460816	189/349 (54%)
Xpr1	NP_001099462.1	SPX_XPR1_like	2..165	CDD:269898	102/162 (63%)
		EXS	268..617	CDD:460816	189/350 (54%)