DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7536 and vtc4

DIOPT Version :9

Sequence 1:	NP_001285398.1	Gene:	CG7536 / 32786	FlyBaseID:	FBgn0030890	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	NP_588142.1	Gene:	vtc4 / 2538788	PomBaseID:	SPCC1322.14c	Length:	721	Species:	Schizosaccharomyces pombe

Alignment Length:	227	Identity:	48/227 - (21%)
Similarity:	89/227 - (39%)	Gaps:	52/227 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFAEHLSAHITPEWRKQYINYEEMKAMLYLAVEEAPSVESVEDDVLKRHFANFDENFFHYCDKE 65
            |||.:.|...:..|::..|:||:::|..:....::....|..|.|            |....:||
pombe     1 MKFGQLLKETLMYEYKYSYVNYDKLKKEIKRRNDQGGWSEEDESD------------FVELLEKE 53

  Fly    66 LKKINTFYSEKLAEATRKFATLNAELKTSIEESERSAKKSKGHKRHAALPDRKARELKLAFSEFY 130
            |.|:.:|...|.||...:       ::...|:::...::...        |....|...|..|..
pombe    54 LDKVYSFQKNKSAEVMER-------IRFCEEQTDEVVRRLDS--------DNPPNENDFAILETE 103

  Fly   131 LSLIL-----LQNYQNLNHTGFRKILKKHDK----------LLRVDTGAKWRQEY----VEASHF 176
            |:.|:     |..:..||:|.|.||:|||||          ..|::....::::|    |:.|..
pombe   104 LTDIMATVHDLAKFSELNYTAFYKIIKKHDKHTGWILKPVFAARLNAKPFFKEQYDLLVVKLSKL 168

  Fly   177 FTNKDIDNIINETETTVTGELEGGDRQRAMKR 208
            :      :.:....:.:.|:...|..|:...|
pombe   169 Y------DFVRTRGSPIKGDSAAGGTQQNFVR 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7536	NP_001285398.1	SPX_XPR1_like	2..156	CDD:269898	37/158 (23%)
		SPX	3..158	CDD:281146	38/169 (22%)
		EXS	258..597	CDD:281164
vtc4	NP_588142.1	COG5036	1..504	CDD:227369	48/227 (21%)
		SPX_VTC2_like	2..134	CDD:269901	37/158 (23%)
		PolyPPase_VTC4_like	188..473	CDD:143623	2/7 (29%)
		VTC1	609..721	CDD:227589
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910