DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dhc16F and DNAH11

DIOPT Version :9

Sequence 1:	NP_523394.1	Gene:	Dhc16F / 32785	FlyBaseID:	FBgn0283476	Length:	4081	Species:	Drosophila melanogaster
Sequence 2:	NP_001264044.1	Gene:	DNAH11 / 8701	HGNCID:	2942	Length:	4516	Species:	Homo sapiens

Alignment Length:	4077	Identity:	1272/4077 - (31%)
Similarity:	2014/4077 - (49%)	Gaps:	468/4077 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   232 QEFKQFLSIIQIRSFSIFRLWKG-------FKVWEKTIKWRKLN---------EARDYLQNNLFI 280
            |::.:..:::......|:..||.       |.:.:..:|:..:|         :....|:...::
Human   670 QKYVEMTTLLDQFESRIYNEWKSNVDEICEFNLNQPLVKFSAINGLLCVNFDPKLVAVLREVKYL 734

  Fly   281 V------IPQLAKAILRMRSDIVQ--------LQRLNFVNVSNIENWHPFYFLETHMR-IYEQLH 330
            :      ||..|.||.:.|:.|::        :|..|.:..:.:|..:|  .:|..:| |.|||.
Human   735 LMLKKQDIPDSALAIFKKRNTILKYIGNLDLLVQGYNKLKQTLLEVEYP--LIEDELRAIDEQLT 797

  Fly   331 KTFT------DFREFIAKTIFRACTDAIQAR---------------------------------G 356
            ...|      |...:|.:.  ||.|..::.|                                 .
Human   798 AATTWLTWQDDCWGYIERV--RAATSELEHRVERTQKNVKVIQQTMRGWARCVLPPRREHRREAA 860

  Fly   357 FYPDDEVNYYPSLKKMREA-----HSFMDRARKRAFCKTLTNFLTYCDMMVYQMLYRITKKSFED 416
            |..:|:.:.:....|:.:.     |:.::..||                     |:: ...|.:.
Human   861 FTLEDKGDLFTKKYKLIQGDGCKIHNLVEENRK---------------------LFK-ANPSLDT 903

  Fly   417 LATSFEVHDEV---GPSEADINKHDRVDKRIEKQRPQDKPQSPFFLAMLRLLPDRIDIEPS---- 474
            .....|..|::   |..:|.::..|...|..|||.   || :|||.|.:.|||..|..:||
Human   904 WKIYVEFIDDIVVEGFFQAIMHDLDFFLKNTEKQL---KP-APFFQAQMILLPPEIVFKPSLDRE 964

  Fly   475 ---------EDIIRIIFQRITGLI--LETVLEIHPFTTDPFFTQYTQPSIMG----RQE------ 518
                     |:::...| |::..:  :.|.|||..:..|       ..:::|    |||
Human   965 AGDGFYDLVEEMLCNSF-RMSAQMNRIATHLEIKNYQND-------MDNMLGLAEVRQEIMNRVV 1021

  Fly   519 ----EVL-YEGAPDLHYLLRADIRFQYNRKNMFVLIRKAYERARLYTQRFHQIRENFEIDNSTDP 578
                :|| :....:.|..|..|.|.::.:.  |:|...|.....:......:|.|.       .|
Human  1022 NVINKVLDFRNTLETHTYLWVDDRAEFMKH--FLLYGHAVSSDEMDAHANEEIPEQ-------PP 1077

  Fly   579 TVLNTERDLQILRAYCDRYCNNVRALDGILEYVFLGLLKLTQTNFKDTVTPVCSRLQNVLATYLP 643
            |:...:..:.|..|.   |....:..|   ..||....|:....||.::..:..:...:...:|.
Human  1078 TLEQFKEQIDIYEAL---YVQMSKFED---FRVFDSWFKVDMKPFKVSLLTIIKKWSWMFQEHLL 1136

  Fly   644 KLAEEETTRLYEEAQDFHGRICYEPHE-----TLEIVAHIRFLDKCSTELDGIFDGIDYVHDLLL 703
            :...:....|.|..::....:..|.:|     .::|:.|:..:.......|.:|:.:   .:.:.
Human  1137 RFVIDSLNELQEFIKETDSGLQRELNEGDHDGLVDIMVHLLAVRSRQRATDELFEPL---KETIT 1198

  Fly   704 IIKDFGIPIDDDSKEDYMDTEDYLNRTRETLEEIREKRQDFINRLEDAMQDDIAALKEDIHEVAI 768
            :::.:|         ..|..:.|:.     |||:.| |.:...::...::.:::.|..  .||.:
Human  1199 LLESYG---------QKMPEQVYIQ-----LEELPE-RWETTKKIAATVRHEVSPLHN--AEVTL 1246

  Fly   769 EALQPWLLDAN------------------SNRLSVTNKLDSMLERLNKCRETADEFLGYQKE--- 812
            ...:..|.||.                  .|..:..:|.:..||.|.      :|.|..|:.
Human  1247 IRKKCILFDAKQAEFRERFRHYAPLGFNAENPYTALDKANEELEALE------EEMLQMQESTRL 1305

  Fly   813 FQIDLTMYDEMASGFYDIRMRQNLYRTWSDWEESLAEWIVSDFNTLNVVDM-VELNSKTIKNCMQ 876
            |::.|..|.:|.....:|::.:.|:........|:..|..:.:..::|..| |||. :..|....
Human  1306 FEVALPEYKQMKQCRKEIKLLKGLWDVIIYVRRSIDNWTKTQWRQIHVEQMDVELR-RFAKEIWS 1369

  Fly   877 FQKYLPENNIVPVLQKSAEAFKEKLPVIGYLRNPNLRARHWAEIEDLLNRKFFQEKDILIQTYED 941
            ..|.:...:....|:.:.:.....|..|..|::|.||.|||.::...:..||...:   ..|..|
Human  1370 LNKEVRVWDAYTGLEGTVKDMTASLRAITELQSPALRDRHWHQLMKAIGVKFLINE---ATTLAD 1431

  Fly   942 VHAFDDVAIGEALMQISSQATGEVQLENMLKGIETTWKETELSIVPHHDAKDVFILAGTEELQAV 1006
            :.|.....:.:.:.:|..:|..|:..|.::..|..||...:.|...|: ...:.:|...|:|...
Human  1432 LLALRLHRVEDDVRRIVDKAVKELGTEKVITEISQTWATMKFSYEVHY-RTGIPLLKSDEQLFET 1495

  Fly  1007 LDDSNVNINTIAASKFVGPIKSKVDEWINAMDQFAKTFESWMDCQGAWIYLEAIF-ASADIQRQL 1070
            |:.:.|.:.|:..||:|.....:|..|.|.::.......:||:.|..|.:||:|| .|.||:.||
Human  1496 LEHNQVQLQTLLQSKYVEYFIEQVLSWQNKLNIADLVIFTWMEVQRTWSHLESIFVCSEDIRIQL 1560

  Fly  1071 PHEAKMFFTVDKSFKETVRQAKKVALALPTMSSVDVHKVLVENNRLLDLISRGLEAYLEVKRVVF 1135
            ..:|:.|..||..|||.:.:..||...|......::::.|.:....|.|..:.|..|||.||:.|
Human  1561 VKDARRFDGVDAEFKELMFKTAKVENVLEATCRPNLYEKLKDLQSRLSLCEKALAEYLETKRIAF 1625

  Fly  1136 PRFYFLSNDELLEILAQTRIPQAVQPHLRKCFDAIYRLEFGSKEGGDGKMVATNDIVAFLSPEGE 1200
            |||||:|:.:||:||::...|:.|..||.|.||:|..|:|     .|.:.|:.:..|...|.|.|
Human  1626 PRFYFVSSADLLDILSKGAQPKQVTCHLAKLFDSIADLQF-----EDNQDVSAHRAVGMYSKEKE 1685

  Fly  1201 KLQFGKGLKARGAVEEWLSKVEEAMFVSCKRYMRFGYQCYPAKEREDWFQDHPNQVVLTVSQVQW 1265
            .:.|....:..|.||.||.::|:.|..:.:..:......|..|.||.|..|.|.||.||.||:.|
Human  1686 YVPFQAECECVGHVETWLLQLEQTMQETVRHSITEAIVAYEEKPRELWIFDFPAQVALTSSQIWW 1750

  Fly  1266 AADI----HRIYEGKERNPLNILEKMAKFEIKCLKDLGALAALTRKNISSLLRKILCALITIDVH 1326
            ..|:    .|:.||.|       ..:..|..|.:..|..|..|....:....|:.:..:.|||||
Human  1751 TTDVGIAFSRLEEGYE-------TALKDFHKKQISQLNTLITLLLGELPPGDRQKIMTICTIDVH 1808

  Fly  1327 AKDSVRMLIEKEVCKASDFNWLKMLRFYWADETETVYSRMAAANIPYYYEYLGAGGVLVLTPLTD 1391
            |:|.|..||.::|.....|.||..||..|.|..:..:..:..|...|:|||||....||:|||||
Human  1809 ARDVVAKLISQKVVSPQAFTWLSQLRHRWEDTQKHCFVNICDAQFQYFYEYLGNSPRLVITPLTD 1873

  Fly  1392 RCYLCLMGAFQMDLGGAPAGPAGTGKTETTKDLAKALAKQCVVFNCSDGLDYKMMGRFFSGLAQC 1456
            |||:.|..:..:.:.||||||||||||||||||.:||.....|||||:.:|||.:|..:.||.|.
Human  1874 RCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGMMVYVFNCSEQMDYKSIGNIYKGLVQT 1938

  Fly  1457 GAWCCFDEFNRIDIEVLSVIAQQLITIRTAKAMRVKRFIFEGREIKINRSCCVFITMNPGYAGRT 1521
            |||.||||||||.:|||||:|.|:..|..|...|.|||:|.|..|.:..|..:||||||||||||
Human  1939 GAWGCFDEFNRISVEVLSVVAVQVKMIHDAIRNRKKRFVFLGEAITLKPSVGIFITMNPGYAGRT 2003

  Fly  1522 ELPDNLKALFRPISMMVPDYALISEVILYSEGFEDPKILARKMVQMYQLCSQQLSQQNHYDFGMR 1586
            |||:||||||||.:|:.||..||.|::|.:|||.|.:.||||.:.:|.||.:.||:|:|||:|:|
Human  2004 ELPENLKALFRPCAMVAPDIELICEILLVAEGFVDARALARKFITLYTLCKELLSKQDHYDWGLR 2068

  Fly  1587 AVKSVLVMAGALKRASPNQREDITLIAALRDSNIPKFLADDAVLFRGILSDLFPGVELPDSQHPH 1651
            |:|||||:||:|||...|:.||..|:.||||.|:||.:.||..:|.|::.||||.:::|..:..|
Human  2069 AIKSVLVVAGSLKRGDKNRPEDQVLMRALRDFNMPKIVTDDIPVFLGLVGDLFPALDVPRRRKLH 2133

  Fly  1652 LEASLRLGLRQKNLQAVPTTIRKCLQLYETMCVRWGVMLVGPTGGGKSVVLHALEFALSHLFENE 1716
            .|..:|....:..||...:.|.|.:||.|.:.||..|.:||..|.|||.:|.    .|:..:.|.
Human  2134 FEQMVRQSTLELRLQPEESFILKVVQLEELLAVRHSVFVVGNAGTGKSKILR----TLNRTYVNM 2194

  Fly  1717 VQDPNFRPVVIQTMNPKAVTMNELYGYVDLKTLEWQDG------LLGL---AVRTATTVEDEIHQ 1772
            .|.|     |...:||||||.:||:|::...|.||:||      .:||   .:|....::.:..:
Human  2195 KQKP-----VWNDLNPKAVTTDELFGFIHHATREWKDGKIVYSYFIGLFSSILREQANLKHDGPK 2254

  Fly  1773 WIMCDGPVDAVWIENLNTVLDDNKMLCLANSERIKLTAWIHMLFEVQDLLQASPATVSRCGMVYV 1837
            ||:.||.:|.:|||:||||:||||:|.||::|||.||.::.:|||:..|..|:||||||.|::||
Human  2255 WIVLDGDIDPMWIESLNTVMDDNKVLTLASNERIALTPFMRLLFEIHHLRSATPATVSRAGILYV 2319

  Fly  1838 DPGDLGWIPLIDTW----REVDMKHKLPAPLAEFCYQLFVGYFDKALK--IERKRAVY-TIHQVL 1895
            :|.||||.|.:.:|    |....|..|..            .|||.:.  :::.|..: ||..:.
Human  2320 NPQDLGWNPYVASWIDRRRHQSEKANLTI------------LFDKYVPACLDKLRTSFKTITSIP 2372

  Fly  1896 GSKV--RLC----CELNSAQFEAVKWSAMSEEQGKELVTKIFAWAVLWAIASNLKDAE----KVS 1950
            .|.:  .||    |.|....        :..:..||:....|.:|.:||....|...:    :..
Human  2373 ESSLVQTLCVLLECLLTPEN--------VPSDSPKEVYEVYFVFACIWAFGGTLLQDQISDYQAD 2429

  Fly  1951 FEEQWSKAI--AQHPNMTLPNFTLWNYRIDLEKMDWGSWIDIMAKFVFDPETSYYDMQVPTVDTT 2013
            |...|.|.:  .:.|:..    |:::|.:|.:......|.|.:|:|..||:.....:.|.|.:|.
Human  2430 FSRWWQKEMKAVKFPSQG----TIFDYYVDHKTKKLLPWADKIAQFTMDPDVPLQTVLVHTTETA 2490

  Fly  2014 KYGYVSDLLFKRGMPVMVTGDTGVGKTVLAISCMKRLSQGNVIPVILNFSAQTSSNRTQEMIEGP 2078
            :..|..:||.::|.|:|:.|:.||||||.....:..||:..::..: .|:..|:|...|:::|.|
Human  2491 RLRYFMELLLEKGKPLMLVGNAGVGKTVFVGDTLASLSEDYIVSRV-PFNYYTTSTALQKILEKP 2554

  Fly  2079 LEKRKKTQLGAPVGKTVIVFIDDVNMPKLDTYGASPAIELLRQFLDFKGFYDREKLYWKEILDVV 2143
            |||:.....|....|.:|.||||:|||::|.||......|:||.:|:..:|||:|:..|||.:
Human  2555 LEKKAGHNYGPGGNKKLIYFIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWYDRQKVMLKEIHN-- 2617

  Fly  2144 LGC---ACAPPGGGRNPLTPRFVRHFALFSLPKPNEETLTQIFNGILRGFL--QTFSSAVRALSE 2203
              |   ||..|..|...:.||..|||.:|:...|:.:.|..|:..|.....  |.|:.::.....
Human  2618 --CQYVACMNPMVGSFTINPRLQRHFTVFAFNFPSLDALNTIYGQIFSFHFQQQAFAPSILRSGP 2680

  Fly  2204 PMVNACVDVYMRVATVMLPTPDKSHYIFNLRDLSKCIQGILQASNLHYNQENQILRLFYHETTRV 2268
            .::.|.:..:..:....|||..|.||||||||||...||||.||.........::.|:.||:.||
Human  2681 TLIQATIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQGILFASPECLKGPLDLIHLWLHESARV 2745

  Fly  2269 FHDRLINIEDKNIFKALMKEVCMDHFNRPVINDN---EPPILFGDFMVFGKPKNERIYDEIRDHT 2330
            :.|:||:.:|.::|:..|.|....:|..  |:.:   :.|:::..|...||..:   |..::|..
Human  2746 YGDKLIDKKDCDLFQRRMLETAYKYFEG--IDSHMLLQQPLIYCHFADRGKDPH---YMPVKDWE 2805

  Fly  2331 KLESVLNDYIADYNSVAVGKQMKLILFQDAMEHTVRLARLLRSDRGNGLLVGVAGMGKQSLTRLA 2395
            .|:::|.:.:.:||.  :...|.|:||:|||:|..|::|:||:.:|..|||||.|.|||||:|||
Human  2806 VLKTILTETLDNYNE--LNAAMHLVLFEDAMQHVCRISRILRTPQGCALLVGVGGSGKQSLSRLA 2868

  Fly  2396 SHVNEYNCWQIEMRRNYDLNAFHEDLRVLYRIAGIDNQPVTFLLIDSQIVEEEFLEDINNILNSG 2460
            :::.....:||.:...|.:.....||..||...|..|.|..|||.|:|:::|.||..||::|.||
Human  2869 AYLRGLEVFQITLTEGYGIQELRVDLANLYIRTGAKNMPTVFLLTDAQVLDESFLVLINDLLASG 2933

  Fly  2461 EVPNLFEGDEFEKII------------LDARDGCNENRKDDPCTRDDIYKFFINRVRNNLHVVMS 2513
            |:|:||..::.:|||            :|:|:.|              :|||:.|||..|.:::.
Human  2934 EIPDLFSDEDVDKIISGIHNEVHALGMVDSRENC--------------WKFFMARVRLQLKIILC 2984

  Fly  2514 MSPVGDAFRRRCRMFPSLVNCTTIDWFTSWPTEALYSVALGLL--TK-IAPKMEDRISLASTTVF 2575
            .||||...|.|.|.||::||||.||||.:||.|||.||:...:  || |.|..:|.|||....|
Human  2985 FSPVGRTLRVRARKFPAIVNCTAIDWFHAWPQEALVSVSRRFIEETKGIEPVHKDSISLFMAHV- 3048

  Fly  2576 MHKTVEDASVKFYKEMKRHYYTTPSSYLELLKLYQNLLKIKNMEIIAKRKRIANGLNKLLETNEV 2640
             |.||.:.|.::|:..:||.||||.|:||.:.|::||||.|..|:..|::|:.||:.||..|...
Human  3049 -HTTVNEMSTRYYQNERRHNYTTPKSFLEQISLFKNLLKKKQNEVSEKKERLVNGIQKLKTTASQ 3112

  Fly  2641 IA-----VMGKELEVMVPQLDEKSAMMK--SLVDNLTKETKQADAVKQSV--LEDEMNAKEKAAV 2696
            :.     :..:|.|:.:...|.::.:.|  ...:.:::|...|||.::.|  ::.|:..|::...
Human  3113 VGDLKARLASQEAELQLRNHDAEALITKIGLQTEKVSREKTIADAEERKVTAIQTEVFQKQRECE 3177

  Fly  2697 AQAISEDAGKDLEIAMPALREAEEALKGLTKADINELKSFTTPPALVQFCMEAVCILL---GVKP 2758
            |         ||..|.|||..|..||..|.:.:::|||:|..||..|.....||.:||   |..|
Human  3178 A---------DLLKAEPALVAATAALNTLNRVNLSELKAFPNPPIAVTNVTAAVMVLLAPRGRVP 3233

  Fly  2759 ---TWASAKAIMADI-NFIKRLFEYDKEHMKEDTLKKVKK-YIDHKDFVPAKFEKVSKVAKSMSM 2818
               :|.:||..|..: :|::.|..|||||:.|:.||.|.: |:...:|.|......|..|..:..
Human  3234 KDRSWKAAKVFMGKVDDFLQALINYDKEHIPENCLKVVNEHYLKDPEFNPNLIRTKSFAAAGLCA 3298

  Fly  2819 WVISMDKFSKVYKVVEPKIKRKEAAEAELKEVMTVLRQKQKELAAVEAKIQGLRDSLEEKQREFQ 2883
            |||::.||.:||..||||.:....|..||......|...:|:|..::..:..|..|.|:...|..
Human  3299 WVINIIKFYEVYCDVEPKRQALAQANLELAAATEKLEAIRKKLVDLDRNLSRLTASFEKATAEKV 3363

  Fly  2884 VIQDNVDLTYGRINRAGRLTSALSDEQVRWRETVKSLTGDLACVPGDVLVAAACVAYLGAFSHEY 2948
            ..|:.|:.|...|..|.||...|..:::||.:::||.......:.||||:.||.|:|:|.|:.:|
Human  3364 RCQEEVNQTNKTIKLANRLVKELEAKKIRWGQSIKSFEAQEKTLCGDVLLTAAFVSYVGPFTRQY 3428

  Fly  2949 RRDM-SALWVSKCREH-KIPSSPEFNLLKVLGDPYEMRQWNVDGLPKDNISIENGIYATRALRWA 3011
            |::: ...||...::. .||.:...:|:.:|.|...:..||.:|||.|.:|.||....|...||.
Human  3429 RQELVHCKWVPFLQQKVSIPLTEGLDLISMLTDDATIAAWNNEGLPSDRMSTENAAILTHCERWP 3493

  Fly  3012 LMIDPQEQANRWIRNMERANNLQVIKMTDSTMMRVLENAVRQGYPVLLEEINETIDPSLRPILQR 3076
            |:||||:|..:||:| :...:|:|..:.....:..:|.|:..|..:|:|.:.|||||.|.|:|.|
Human  3494 LVIDPQQQGIKWIKN-KYGMDLKVTHLGQKGFLNAIETALAFGDVILIENLEETIDPVLDPLLGR 3557

  Fly  3077 ETYRFEGRTYLKLGDMVIDYDDNFKLYMTTKLPNPHYLPEVCINVTLVNFLVTESGLEDQLLADI 3141
            .|.: :|: |:::||...:::.||:|.:.|||.||||.||:....||:||.|||.|||.||||::
Human  3558 NTIK-KGK-YIRIGDKECEFNKNFRLILHTKLANPHYKPELQAQTTLLNFTVTEDGLEAQLLAEV 3620

  Fly  3142 VAIELPAMEIQRNDLVVKINSDKQQLLALEDKVLKLLFNSEGNILDDEELVETLNDAKETSLIIA 3206
            |:||.|.:|..:..|....|..|.:|..|||.:|..|..:||:.|||.:|||.|...|.|...|.
Human  3621 VSIERPDLEKLKLVLTKHQNDFKIELKYLEDDLLLRLSAAEGSFLDDTKLVERLEATKTTVAEIE 3685

  Fly  3207 ARLIDTEETEKVITASRERYRILASRGAILYFVVAGLAEIDPMYQYSLKYFTQVFCNVLRLDHPP 3271
            .::|:.:|.|:.|..:||.||.:|:|.::||||:..|.:|:|:||:|||.|..:|...:......
Human  3686 HKVIEAKENERKINEARECYRPVAARASLLYFVINDLQKINPLYQFSLKAFNVLFHRAIEQADKV 3750

  Fly  3272 QSVEVRISTLMTDELRAIFDNISRGLFENHKIIFSFLLALSVERQEGRVTEEEFLFLSRGPVGNI 3336
            :.::.|||.||.....|:|...|:.|||..|:.|...:|..:..::..:...|..||.|..|.:
Human  3751 EDMQGRISILMESITHAVFLYTSQALFEKDKLTFLSQMAFQILLRKKEIDPLELDFLLRFTVEH- 3814

  Fly  3337 RTKIQPAKIKMSQIEWD---SCIFLEDNFSSFFSGLTDELDKPFFIQMQENKEVFDFAQTNQPPT 3398
             |.:.|.....|| .|.   :...:|:     |.|:..:::       ...|:...:.::..|..
Human  3815 -THLSPVDFLTSQ-SWSAIKAIAVMEE-----FRGIDRDVE-------GSAKQWRKWVESECPEK 3865

  Fly  3399 DK----WNKRLRVFHKLMFISAFRKPRFLLNVVCYLQSTVGKYFTEASGGTQLSSV--YLDTSAV 3457
            :|    |.|: .:..||:.:.|.|..|....:..:::..:|..:.|.   |:|..|  :.::|..
Human  3866 EKLPQEWKKK-SLIQKLILLRAMRPDRMTYALRNFVEEKLGAKYVER---TRLDLVKAFEESSPA 3926

  Fly  3458 TPLIFVLSTGSDPMSGFLKFTTQMQFT---DKYYSISLGQGQGPLAENLIEKSLRLGHWVFLQNC 3519
            ||:.|:||.|.|.:........::.||   .|::::||||||..:||..:||:.:.||||.|||.
Human  3927 TPIFFILSPGVDALKDLEILGKRLGFTIDSGKFHNVSLGQGQETVAEVALEKASKGGHWVILQNV 3991

  Fly  3520 HLATSFMQTLETIVRNLTLGITKAHVDFRLYLSSMPIQT-----FPISVLQNSVKITNEPPKGIK 3579
            ||...::.|||.::...:.|   :|.|:|:::|:....|     .|..:|:||:|||||||.|:.
Human  3992 HLVAKWLGTLEKLLERFSQG---SHRDYRVFMSAESAPTPDEHIIPQGLLENSIKITNEPPTGML 4053

  Fly  3580 ANVFGALTDLKQDFFEQHIQNGNWRAIVFGLCMFHAVLLERRKFGPLGWNITYEFSESDRECGLK 3644
            ||:..||.:..||..|...:...:::|:|.||.|||.:..|.:|||.||:.:|.|:..|......
Human  4054 ANLHAALYNFDQDTLEICSKEQEFKSILFSLCYFHACVAGRLRFGPQGWSRSYPFNPGDLTICAS 4118

  Fly  3645 TLDFFIDREVLDEIPWEAILYINGDITWGGRVTDYWDLRCLRTILTIFSSKRIIQPDYKYCRGDS 3709
            .|..::  |...::|||.:.|:.|:|.:||.:||.||.:..|..|..|.:..:.:.:.....|
Human  4119 VLYNYL--EANSKVPWEDLRYLFGEIMYGGHITDDWDRKLCRVYLEEFMNPSLTEDELMLAPG-- 4179

  Fly  3710 YYRDPRKKTLTEYSAYVQGFPVLEDPEIFGMNQNANIVFQTKETAFFINTLLLGQPRSAADEGQA 3774
             :..|.......|..|::.....|.|.::|::.||.|.|.|..:.....|||..|||:|..
Human  4180 -FAAPPYLDYAGYHQYIEEMLPPESPALYGLHPNAEIEFLTVTSNTLFRTLLEMQPRNALS---- 4239

  Fly  3775 MENEIAQQTIARIQKALATKIKREPIHDTLSVLDAKGQVPS-LTIVLVQEIDRFNIALGIIHDSL 3838
             .:|:.|.|..:::..|...:::.|....::.:..|....| ..:|..||.:|.||.:..|..||
Human  4240 -GDELGQSTEEKVKNVLDDILEKLPEEFNMAEIMQKNSNRSPYVLVCFQECERMNILIREIRISL 4303

  Fly  3839 VNLSKAIKGLVVMSEELENVFKALLSNQVPASWAKRSFLSIKPLPSYISDFQRRIDFIQQWAEN- 3902
            ..|..::||.:.:|..:|....||..:.||.:|:|.::.|...|..:.:|...|...:..|.::
Human  4304 EQLDLSLKGELALSPAVEAQQFALSYDTVPDTWSKLAYPSTYGLAQWFNDLLLRCRELDTWTQDL 4368

  Fly  3903 GAPRSYWISGFFFPQSFLTGVLQTYARRRVLPIDSLKIDFDVFERELVQQDFFEMHTNNMSDQKL 3967
            ..|...|:||||.||||||.::||.||:...|:|..::..||.::  .::|
Human  4369 TLPAVVWLSGFFNPQSFLTAIMQTMARKNEWPLDKTRLTADVTKK--TKED-------------- 4417

  Fly  3968 YGNLPECTDAIINVHGIFIEAARWDLSKGGLCDANFGELFSRMPVVRFKPCLEISPTVR------ 4026
            ||:.|. ..|.:  ||:|:|.||||...|.:.:|...||...|||:..|    .:|..|
Human  4418 YGHPPR-EGAYL--HGLFMEGARWDTQAGTIVEARLKELACPMPVIFAK----ATPVDRQETKQT 4475

  Fly  4027 YEAPLYKTQQRSGVLSTTGHSTNFILAVLLRSHNDPEFWIMRGTALV 4073
            ||.|:|:|:.|         ..::|....|:|......|::.|.||:
Human  4476 YECPVYRTKLR---------GPSYIWTFRLKSEEKTAKWVLAGVALL 4513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhc16F	NP_523394.1	DHC_N2	829..1234	CDD:285579	114/406 (28%)
		P-loop_NTPase	1373..1603	CDD:304359	137/229 (60%)
		P-loop_NTPase	1687..1832	CDD:304359	64/153 (42%)
		P-loop_NTPase	1994..2264	CDD:304359	93/274 (34%)
		P-loop_NTPase	2343..2613	CDD:304359	118/284 (42%)
		MT	2625..2957	CDD:289543	106/349 (30%)
		AAA_9	2985..3201	CDD:289547	92/215 (43%)
		Dynein_heavy	3342..4066	CDD:281078	216/748 (29%)
DNAH11	NP_001264044.1	Stem. /evidence=ECO:0000250	1..1854		288/1279 (23%)
		DHC_N1	239..812	CDD:285571	27/143 (19%)
		DHC_N2	1319..1722	CDD:285579	114/412 (28%)
		P-loop_NTPase	1855..2084	CDD:304359	137/228 (60%)
		AAA 1. /evidence=ECO:0000250	1855..2076		131/220 (60%)
		AAA 2. /evidence=ECO:0000250	2136..2366		92/250 (37%)
		P-loop_NTPase	2169..2313	CDD:304359	63/152 (41%)
		P-loop_NTPase	2471..2741	CDD:304359	93/274 (34%)
		AAA 3. /evidence=ECO:0000250	2472..2719		85/251 (34%)
		AAA 4. /evidence=ECO:0000250	2817..3066		107/266 (40%)
		P-loop_NTPase	2818..3085	CDD:304359	118/284 (42%)
		Stalk. /evidence=ECO:0000250	3072..3403		105/339 (31%)
		MT	3097..3441	CDD:289543	108/352 (31%)
		AAA 5. /evidence=ECO:0000250	3459..3686		96/229 (42%)
		AAA_9	3468..3680	CDD:289547	92/214 (43%)
		Dynein_heavy	3820..4506	CDD:281078	215/747 (29%)
		AAA 6. /evidence=ECO:0000250	3896..4122		80/231 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5245
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1492at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100025
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.720