DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dhc16F and DYNC2H1

DIOPT Version :9

Sequence 1:	NP_523394.1	Gene:	Dhc16F / 32785	FlyBaseID:	FBgn0283476	Length:	4081	Species:	Drosophila melanogaster
Sequence 2:	NP_001073932.1	Gene:	DYNC2H1 / 79659	HGNCID:	2962	Length:	4314	Species:	Homo sapiens

Alignment Length:	4160	Identity:	1049/4160 - (25%)
Similarity:	1827/4160 - (43%)	Gaps:	781/4160 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   222 NFFTPLDQWQQEFKQFLSIIQIRSF-SIFRLWKGFKVWEKTIKWRKLNEARDYLQNNLFIVIPQL 285
            :|:..:||...:.::.:.:....:| .|.:..|.....:..|.|....|...|:|        :|
Human   622 HFYNSIDQQMIQSQRPMMLQSALAFEQIIKNSKAGSGGKSQITWDNPKELEGYIQ--------KL 678

  Fly   286 AKAILRMRSDIVQLQRLNFVNVSNIENWHPFYFLETHMRIYEQLHKTFTDFREFIAKTIFRACTD 350
            ..|..|:.::..:|::           ||                   |.|.|   |.:.....|
Human   679 QNAAERLATENRKLRK-----------WH-------------------TTFCE---KVVVLMNID 710

  Fly   351 AIQARGFYPDDEVNYYPSLKKMR------EAHSFMDRARKRAFCKTLTNFLTYCDMMVYQ----- 404
            .::.:..:.|       .|:::|      ||..|.                 ..||..::
Human   711 LLRQQQRWKD-------GLQELRTGLATVEAQGFQ-----------------ASDMHAWKQHWNH 751

  Fly   405 MLYRITKKSFEDLATSFEVHDEVGPSEADINKHDRVDKRIEKQRPQDKP-----QSPFFLAMLRL 464
            .||:..:..::   ...|..:|..|   :||    :|...::.|.|.:|     ::.::..|.|.
Human   752 QLYKALEHQYQ---MGLEALNENLP---EIN----IDLTYKQGRLQFRPPFEEIRAKYYREMKRF 806

  Fly   465 --LPDR---IDIEPSEDIIRIIFQRITGLILETVLEIHPFTTDPFFTQYTQ--------PSIMGR 516
              :|::   :.....|.|..|:..|               ....|.|.:::        .:::.:
Human   807 IGIPNQFKGVGEAGDESIFSIMIDR---------------NASGFLTIFSKAEDLFRRLSAVLHQ 856

  Fly   517 QEEVLYEGAPDLHYLLRADIRFQYNRKNMFVLIRKAYERARLYTQRFHQIRENFEIDNSTDPTVL 581
            .:|.:..|..|:..|:         .|::|.:               |...:||:........|
Human   857 HKEWIVIGQVDMEALV---------EKHLFTV---------------HDWEKNFKALKIKGKEV- 896

  Fly   582 NTERDLQILRAYC-DRYCNNVR-ALDGILEYVF----LGLLKLTQTNFKDTVTPVCSRLQNVLAT 640
              ||....::..| :..||.|: .:|.:::.:|    |.|.|..|.:..:..|.|...::  :.|
Human   897 --ERLPSAVKVDCLNINCNPVKTVIDDLIQKLFDLLVLSLKKSIQAHLHEIDTFVTEAME--VLT 957

  Fly   641 YLPKLAEE----------------ETTRLYEEAQDFHGRICYEPHETLEIVAHIRF-LDKCSTEL 688
            .:|:..||                |...|::||:|.:..:.......||.:::::. .||....:
Human   958 IMPQSVEEIGDANLQYSKLQERKPEILPLFQEAEDKNRLLRTVAGGGLETISNLKAKWDKFELMM 1022

  Fly   689 DGIFDGIDYVHDLLLIIKDFGIPID------------------------DDSK--EDYMDTEDYL 727
            :.        |.|:  |||   .|:                        |..|  :|.::|..:
Human  1023 ES--------HQLM--IKD---QIEVMKGNVKSRLQIYYQELEKFKARWDQLKPGDDVIETGQH- 1073

  Fly   728 NRTRETLEEIREKRQDFINRLEDAMQDDIAALKEDIHEVAIEALQPWLLDANSNRLSVTNKLDSM 792
            |...::.:.|:||:.:|         ||:...::.:.:           |.:..||...|  .|:
Human  1074 NTLDKSAKLIKEKKIEF---------DDLEVTRKKLVD-----------DCHHFRLEEPN--FSL 1116

  Fly   793 LERLNKCRETADEFLGYQKEFQIDLTMYDEMASGFYDIRMRQNLYRTWSDWEESLAEWIVSDFNT 857
            ...::|..|:..:...:.:|||   ..:.|||:..: |..|...|.    :||.|..|    .:.
Human  1117 ASSISKDIESCAQIWAFYEEFQ---QGFQEMANEDW-ITFRTKTYL----FEEFLMNW----HDR 1169

  Fly   858 LNVVDMVELNSKTIKNCMQFQKYLPENNIVPV-LQKSAEAFKEKLPVIGYLRNPNLRARHWAEIE 921
            |..|:                    |::::.| ||...:.:|..:|::.|:|..:|...||.::.
Human  1170 LRKVE--------------------EHSVMTVKLQSEVDKYKIVIPILKYVRGEHLSPDHWLDLF 1214

  Fly   922 DLLN--RKFFQEKDILIQTYEDVHAFDDVAIGEA--LMQISSQATGEVQLENMLKGIETTWKETE 982
            .||.  |....||.:    :.|:....|..:.:|  |..::|:|.|||.:...|:.::.......
Human  1215 RLLGLPRGTSLEKLL----FGDLLRVADTIVAKAADLKDLNSRAQGEVTIREALRELDLWGVGAV 1275

  Fly   983 LSIVPHHD--AKDVFILAGTEELQAVLDDSNVNINTIAASKFVGPIKSKVDEWINAMDQFAKTFE 1045
            .:::.:.|  ::.:.::...:::...:.|:...:.::..|.:....:.||..|...:.:..:..:
Human  1276 FTLIDYEDSQSRTMKLIKDWKDIVNQVGDNRCLLQSLKDSPYYKGFEDKVSIWERKLAELDEYLQ 1340

  Fly  1046 SWMDCQGAWIYLEAIFASADIQRQLPHEAKMFFTVDKSFKETVRQAKKVALALPTMSSVDVHKVL 1110
            :....|..|:|||.||.    :..||.|...|..||:.|:..:...||........:...:...|
Human  1341 NLNHIQRKWVYLEPIFG----RGALPKEQTRFNRVDEDFRSIMTDIKKDNRVTTLTTHAGIRNSL 1401

  Fly  1111 VENNRLLDLISR---GLEAYLEVKRVVFPRFYFLSNDELLEILAQTRIPQAVQPHLRKCFDAIYR 1172
            :   .:||.:.|   .|..:||.||..||||||:.:|:|||||.|:..|..:|.||:|.|..|..
Human  1402 L---TILDQLQRCQKSLNEFLEEKRSAFPRFYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINS 1463

  Fly  1173 LEFGSKEGGDGKMVATNDIVAFLSPEGEKLQFGKGLKARGAVEEWLSKVEEAMFVSCKRYMRFGY 1237
            :.|..|         :..|.|..|.|||.:.|...:.....||.||:.:...|..:.::.::
Human  1464 VCFDEK---------SKHITAMKSLEGEVVPFKNKVPLSNNVETWLNDLALEMKKTLEQLLK--- 1516

  Fly  1238 QCYPAKEREDWFQD---HPNQVVLTVSQVQWAADI------HRIYEGKERNPLNILEKMAKFEIK 1293
            :|...........|   .|:|::....|:::..|:      |.::: .|...:|.||:....:..
Human  1517 ECVTTGRSSQGAVDPSLFPSQILCLAEQIKFTEDVENAIKDHSLHQ-IETQLVNKLEQYTNIDTS 1580

  Fly  1294 CLKDLGALAALTRKNISSLLRKILCALITIDVHAKDSVRMLIEKEVCKASDFNWLKMLRFYWADE 1358
            . :|.|       ...|.:|...|.|||...:|..|.|:.|.:.:|....|:.|.|.||||...:
Human  1581 S-EDPG-------NTESGILELKLKALILDIIHNIDVVKQLNQIQVHTTEDWAWKKQLRFYMKSD 1637

  Fly  1359 TETVYSRMAAANIPYYYEYLGAGGVLVLTPLTDRCYLCLMGAFQMDLGGAPAGPAGTGKTETTKD 1423
             .|...:|..:...|.|||.|....||.|||||:|||.|..|.:|.|||.|.|||||||||:.|.
Human  1638 -HTCCVQMVDSEFQYTYEYQGNASKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKA 1701

  Fly  1424 LAKALAKQCVVFNCSDGLDYKMMGRFFSGLAQCGAWCCFDEFNRIDIEVLSVIAQQLITIRTAKA 1488
            |...|.:|.:||||.:|:|.|.|||.|.||.:||||.|||||||::..|||.::.|:.||:  .|
Human  1702 LGGLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEESVLSAVSMQIQTIQ--DA 1764

  Fly  1489 MRVKRFIFE--GREIKINRSCCVFITMNP---GYAGRTELPDNLKALFRPISMMVPDYALISEVI 1548
            ::..|.:.|  |:|:::|.:..:||||||   ||.||.:||||||.||||::|..||..||:|||
Human  1765 LKNHRTVCELLGKEVEVNSNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSHPDNELIAEVI 1829

  Fly  1549 LYSEGFEDPKILARKMVQMYQLCSQQLSQQNHYDFGMRAVKSVLVMAGALKR------ASPNQRE 1607
            ||||||:|.|:|:||:|.::.|..:.|:.|.|||:|:||:|:||..:|.|.|      .:.|..|
Human  1830 LYSEGFKDAKVLSRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRGSGNLLRQLNKSGTTQNANE 1894

  Fly  1608 DITLIAALRDSNIPKFLADDAVLFRGILSDLFPGVELPDSQHPHLEASLRLGLRQKNLQAVPTTI 1672
            ...::.|||.:.:.||...|...|..::.|:|||:||.:.::..|.|:|:....:.|.:.:|..|
Human  1895 SHIVVQALRLNTMSKFTFTDCTRFDALIKDVFPGIELKEVEYDELSAALKQVFEEANYEIIPNQI 1959

  Fly  1673 RKCLQLYETMCVRWGVMLVGPTGGGKSVVLHALEFALSHLFENEVQDPNFRPVVIQ-TMNPKAVT 1736
            :|.|:|||.:|.|.||::|||:|.|||.:...|..||....:          ||.| ||||||:.
Human  1960 KKALELYEQLCQRMGVVIVGPSGAGKSTLWRMLRAALCKTGK----------VVKQYTMNPKAMP 2014

  Fly  1737 MNELYGYVDLKTLEWQDGLLGLAVRTATTVEDEIHQWIMCDGPVDAVWIENLNTVLDDNKMLCLA 1801
            ..:|.|::|:.|.||.||:|..:.|.......::..||:|||.:|..|||:||:|||||::|.:.
Human  2015 RYQLLGHIDMDTREWSDGVLTNSARQVVREPQDVSSWIICDGDIDPEWIESLNSVLDDNRLLTMP 2079

  Fly  1802 NSERIKLTAWIHMLFEVQDLLQASPATVSRCGMVYVDPGDLGWIPLIDTWREVDMKHKLPAPLAE 1866
            :.|||:....::.:||..||..|||||:||.||:::...:.....||.:|        |....||
Human  2080 SGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEETDLNSLIKSW--------LRNQPAE 2136

  Fly  1867 FCYQL--FVG-YFDKALKIERKRAVYTIHQVLGSKVRLCCELNSAQFEAVKWSAMSEEQG----K 1924
            :...|  ::| ||:|||:...|:..|.:...|...|               .:.:|...|    .
Human  2137 YRNNLENWIGDYFEKALQWVLKQNDYVVETSLVGTV---------------MNGLSHLHGCRDHD 2186

  Fly  1925 ELVTKIFAWAVLWAIASNLKDAEKVSFEEQ---WSKAIAQHPNMTLPNFTLWNYRIDLEKMDWGS 1986
            |.:..:     :..:..||....::.|.::   |::   :.|    |:|
Human  2187 EFIINL-----IRGLGGNLNMKSRLEFTKEVFHWAR---ESP----PDF---------------- 2223

  Fly  1987 WIDIMAKFVFDPETSYYD----------MQVP---TVDTTKYGYVSDLL----FKRGM------- 2027
                     ..|..:|||          ::.|   |.|....|....::    .:||:
Human  2224 ---------HKPMDTYYDSTRGRLATYVLKKPEDLTADDFSNGLTLPVIQTPDMQRGLDYFKPWL 2279

  Fly  2028 ------PVMVTGDTGVGKTVLAISCMKRLSQGNVIPVILNFSAQTSSNRTQEMIEGPLEKRKKT- 2085
                  |.::.|..|.||.:|......:|....:..|  :.||||:|...       |:|..:|
Human  2280 SSDTKQPFILVGPEGCGKGMLLRYAFSQLRSTQIATV--HCSAQTTSRHL-------LQKLSQTC 2335

  Fly  2086 -QLGAPVGKT--------VIVFIDDVNMPKLDTYGASPAIELLRQFLDFKGFYDREKLYWKEILD 2141
             .:....|:.        :::::.|:|:||||.:|.|..:..|:|.|.::|||| |.|.|..:.:
Human  2336 MVISTNTGRVYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYD-ENLEWVGLEN 2399

  Fly  2142 VVLGCACAPPGG--GRNPLTPRFVRHFALFSLPKPNEETLTQIFNGILRGFLQT---------FS 2195
            :.: .|....||  ||:.||.||.....|.|:..|..|.|..|:...|...|..         .|
Human  2400 IQI-VASMSAGGRLGRHKLTTRFTSIVRLCSIDYPEREQLQTIYGAYLEPVLHKNLKNHSIWGSS 2463

  Fly  2196 SAVRALSEPMVNACVDVYMRVATVMLPTPDKSHYIFNLRDLSKCIQGILQ------ASN--LHYN 2252
            |.:..|:..|    |.||.:| .......|.|||.|....|::.:.|:.:      :||  |.|
Human  2464 SKIYLLAGSM----VQVYEQV-RAKFTVDDYSHYFFTPCILTQWVLGLFRYDLEGGSSNHPLDY- 2522

  Fly  2253 QENQILRLFYHETTRVFHDRLINIEDKNIFKALMKEVCMDHFNRPVINDNE-------------- 2303
                :|.:..:|..|:|.|:::..::.::|..::..|....:...::::..
Human  2523 ----VLEIVAYEARRLFRDKIVGAKELHLFDIILTSVFQGDWGSDILDNMSDSFYVTWGARHNSG 2583

  Fly  2304 ---------PPILFGDFMVFGKPKNERIYDEIRDHTKLESVLNDYIADYNSVAVGKQMKLILFQD 2359
                     ||        .|||..:      .:.|.|:.|:...:..|.  ...:.:.::||.:
Human  2584 ARAAPGQPLPP--------HGKPLGK------LNSTDLKDVIKKGLIHYG--RDNQNLDILLFHE 2632

  Fly  2360 AMEHTVRLARLLRSDRGNGLLVGVAGMGKQSLTRLASHVNEYNCWQIEMRRNYDLNAFHEDLRVL 2424
            .:|:..|:.|:|....|:.||.|.:|:|::::|.|.||::....:..::.|.|:|..|..||:.:
Human  2633 VLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTITSLVSHMHGAVLFSPKISRGYELKQFKNDLKHV 2697

  Fly  2425 YRIAGIDNQPVTFLLIDSQIVEEEFLEDINNILNSGEVPNLFEGDEFEKIILDARDGCNENRKDD 2489
            .::|||:.|.|..||.|.|.|...|||.||::|:|||||.|:..:|.|.::|..:|..:::....
Human  2698 LQLAGIEAQQVVLLLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEELEPLLLPLKDQASQDGFFG 2762

  Fly  2490 PCTRDDIYKFFINRVRNNLHVVMSMSPVGDAFRRRCRMFPSLVNCTTIDWFTSWPTEALYSVALG 2554
            |     ::.:|..|::.|||:|:.|......|...|...|:|.....:.|...|...::..:...
Human  2763 P-----VFNYFTYRIQQNLHIVLIMDSANSNFMINCESNPALHKKCQVLWMEGWSNSSMKKIPEM 2822

  Fly  2555 LLTKI--APKMEDRISLASTTVFMHKTVED-----------ASVKFYKEMKRHYYTTPSSYLELL 2606
            |.::.  ..|..|:           |..|:           .|.....|..:.|..|||.|:..|
Human  2823 LFSETGGGEKYNDK-----------KRKEEKKKNSVDPDFLKSFLLIHESCKAYGATPSRYMTFL 2876

  Fly  2607 KLYQNLLKIKNMEIIAKRKRIANGLNKLLETNEVIAVMGKELEVMVPQLDEKSAMMKSLVDNLTK 2671
            .:|..:...|..|::.::..:..|::||           .|.:.:|.:|:.|:.....|:
Human  2877 HVYSAISSSKKKELLKRQSHLQAGVSKL-----------NEAKALVDELNRKAGEQSVLL----- 2925

  Fly  2672 ETKQ--ADAVKQSVLEDEMNAKEKAA----VAQAISEDAGK----------DLEIAMPALREAEE 2720
            :|||  |||..|.:.....:|.|:..    :...|:|:..|          :|:...|.:.||:.
Human  2926 KTKQDEADAALQMITVSMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKL 2990

  Fly  2721 ALKGLTKADINELKSFTTPPALVQFCMEAVCILLGVKPT-WASAKAIMADINFIKRLFEYDKEHM 2784
            |:..:....::|::|...||.:::..:|.|..|:|:..| |.|.|:.:|.....:.:..:|..::
Human  2991 AVGNIKPESLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVREDIATFDARNI 3055

  Fly  2785 KEDTLKKVKKYI--DHKDFVPAKFEKVSKVAKSMSMWVISMDKFSKVYKVVEPKIKRKEAAEAEL 2847
            .::..:.|::.:  :...|.|...::.|..|..::.||.:..::|.|.:.:.|....:...|:.|
Human  3056 SKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLETEQAGLESNL 3120

  Fly  2848 KEVMTVLRQKQKELAAVEAKIQGLRDSLEEKQREFQVIQDNVDLTYGRINRAGRLTSALSDEQVR 2912
            |:.....|:.::.|.:|..|:..|::..:.:..|...::..|......|..|..|.:.|..|..|
Human  3121 KKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLINQLDREHKR 3185

  Fly  2913 WRETVKSLTGDLACVPGDVLVAAACVAYLGAFSHEYRRDMSALWVSKCREHKIPSSPEFNLLKVL 2977
            |...|..:|.:||.:|....:|||.:.||.|.....|:.....|.      |.....:|:|.:.|
Human  3186 WNAQVVEITEELATLPKRAQLAAAFITYLSAAPESLRKTCLEEWT------KSAGLEKFDLRRFL 3244

  Fly  2978 GDPYEMRQWNVDGLPKDNISIENGIYATRAL---RWA----LMIDPQEQANRWIRNMERANNLQV 3035
            ....|...|..:|||.|::||||.:...:.:   .|:    .:|||..||..|::...:.:.|:|
Human  3245 CTESEQLIWKSEGLPSDDLSIENALVILQIIGLKSWSRVCPFLIDPSSQATEWLKTHLKDSRLEV 3309

  Fly  3036 IKMTDSTMMRVLENAVRQGYPVLLEEINETIDPSLRPILQRETYRFEGRTYLKLGDMVIDYDDNF 3100
            |...||..:..||.|||.|..::::|: :.::|.|.|:|:|:......|..:::||.:|||::.|
Human  3310 INQQDSNFITALELAVRFGKTLIIQEM-DGVEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNEEF 3373

  Fly  3101 KLYMTTKLPNPHYLPEVCINVTLVNFLVTESGLEDQLLADIVAIELPAMEIQRNDLVVKINSDKQ 3165
            :|:::|:.|||...|:....||.|||..|.|||..||||..:..|.|.:|.|:..|:.:....|.
Human  3374 RLFLSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKI 3438

  Fly  3166 QLLALEDKVLKLLFNSEGNILDDEELVETLNDAKETSLIIAARLIDTEETEKVITASRERYRILA 3230
            ||..||:.:|:.|..|:||||::::|:|:||..|.:|.:|...|.::.:.:..:...|:.|..||
Human  3439 QLAKLEESLLETLATSQGNILENKDLIESLNQTKASSALIQESLKESYKLQISLDQERDAYLPLA 3503

  Fly  3231 SRGAILYFVVAGLAEIDPMYQYSLKYFTQVFCNVLRLDHPPQSVEVRISTLMTDELRAIFDNISR 3295
            ...:.:||:::.|::|:.||::||..|.::|...|:.....::.|.||.:|::.....:::.|.|
Human  3504 ESASKMYFIISDLSKINNMYRFSLAAFLRLFQRALQNKQDSENTEQRIQSLISSLQHMVYEYICR 3568

  Fly  3296 GLFENHKIIFS--FLLALSVERQEGRVTEEEFLFLSRGPVGNIRTK------------------- 3339
            .||:..:::|:  |:..:..|..:    |.|:...:...||::..|
Human  3569 CLFKADQLMFALHFVRGMHPELFQ----ENEWDTFTGVVVGDMLRKADSQQKIRDQLPSWIDQER 3629

  Fly  3340 ---IQPAKIKMSQIEWDSCIFLEDN--FSSFFSGLTDELDKPFFIQMQENKEVFDFAQTNQPPTD 3399
               :...||.:..:....|  .||.  :.::::....|.:.|..:.
Human  3630 SWAVATLKIALPSLYQTLC--FEDAALWRTYYNNSMCEQEFPSILA------------------- 3673

  Fly  3400 KWNKRLRVFHKLMFISAFRKPRFLLNVVCYLQSTVGKYFTEASGGTQLS-------SVYLDTSAV 3457
               |::.:|.:::.:.|.|..|        |||.:..:..:..|..::|       .:|.:|..:
Human  3674 ---KKVSLFQQILVVQALRPDR--------LQSAMALFACKTLGLKEVSPLPLNLKRLYKETLEI 3727

  Fly  3458 TPLIFVLSTGSDPMSGFLKFTTQMQFTDKYYSISLGQGQGPLAENLIEKSLRLGHWVFLQNCHLA 3522
            .|::.::|.|:||.....:.....:..:.|:.:::||||..||..::::..|.|.|:.|:|.||.
Human  3728 EPILIIISPGADPSQELQELANAERSGECYHQVAMGQGQADLAIQMLKECARNGDWLCLKNLHLV 3792

  Fly  3523 TSFMQTLETIVRNLTLGITKAHVDFRLYLSSMPIQTFPISVLQNSVKITNEPPKGIKANVFGALT 3587
            .|::..||..:..|....|     |||:|::.....|...:||:|:|||.|.|.|:|.|:.....
Human  3793 VSWLPVLEKELNTLQPKDT-----FRLWLTAEVHPNFTPILLQSSLKITYESPPGLKKNLMRTYE 3852

  Fly  3588 DLKQDFFEQHIQNGNWRA-IVFGLCMFHAVLLERRKFGPLGWNITYEFSESDRECGLKTLDFFID 3651
            ....:...:  ::...|| .:|.|..|||...|||.:.|.||...||||.||...|...:|...|
Human  3853 SWTPEQISK--KDNTHRAHALFSLAWFHAACQERRNYIPQGWTKFYEFSLSDLRAGYNIIDRLFD 3915

  Fly  3652 REVLDEIPWEAILYINGDITWGGRVTDYWDLRCLRTILTIFSSKRIIQPDYKYCRGDSYYRDPRK 3716
            .  ..::.||.:..:..:..:|||:.:|:|||.|::.|..|.:..:|          ..:....|
Human  3916 G--AKDVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFFNSSVI----------DVFNQRNK 3968

  Fly  3717 KTLTEYS-------------AYVQGFPVLEDPEIFGMNQNANIVFQTKETAFFINTL-LLGQPRS 3767
            |::..||             |.::..|..:.|..||:..|.....|...::..|:.| :||:..:
Human  3969 KSIFPYSVSLPQSCSILDYRAVIEKIPEDDKPSFFGLPANIARSSQRMISSQVISQLRILGRSIT 4033

  Fly  3768 AADEGQAMENEIAQQTIARIQKALATKIKREP--IHDTLSVLDAKGQVPSLTIVLVQEIDRFNIA 3830
            |   |...:.||....::.:.. |..|:.:..  ||..:...:.:...|.|:.:::::.:...:.
Human  4034 A---GSKFDREIWSNELSPVLN-LWKKLNQNSNLIHQKVPPPNDRQGSPILSFIILEQFNAIRLV 4094

  Fly  3831 LGIIHDSLVNLSKAIKGLVVMSEELENVFKALLSNQVPASWAKRSFLSIKPLPSYISDFQRRIDF 3895
            .. :|.||..|||.|:|..::|.|::.:..|||:.:.|.:|..:......|| .|:.....|...
Human  4095 QS-VHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLAWQSKWEGPEDPL-QYLRGLVARALA 4157

  Fly  3896 IQQWAENGAPRSYW-----ISGFFFPQSFLTGVLQTYARRRVLPIDSLKIDFDVFERELVQQDFF 3955
            ||.|.:....::..     :|..|.|.:||..:.|..||.....:||||              |.
Human  4158 IQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLK--------------FV 4208

  Fly  3956 EMHTNNMSDQKLYGNLPECTDAIINVHGIFIEAARWD---LSKGGLCDANFGELFSRMPVVRFKP 4017
            ......:.:.||.          |.:.|:.:|...:|   ||:..|...:...:.         |
Human  4209 ASWKGRLQEAKLQ----------IKISGLLLEGCSFDGNQLSENQLDSPSVSSVL---------P 4254

  Fly  4018 CL----------EISPTVRYEAPLYKTQQRSGVLSTTGHSTNFILAVLLRSHNDPEFWIMRGTAL 4072
            |.          ..||......|:|.:.:|..|:      ||  :.|....:.|.  ||..|.||
Human  4255 CFMGWIPQDACGPYSPDECISLPVYTSAERDRVV------TN--IDVPCGGNQDQ--WIQCGAAL 4309

Fly 4073 4072
Human 4310 4309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhc16F	NP_523394.1	DHC_N2	829..1234	CDD:285579	100/414 (24%)
		P-loop_NTPase	1373..1603	CDD:304359	126/240 (53%)
		P-loop_NTPase	1687..1832	CDD:304359	61/145 (42%)
		P-loop_NTPase	1994..2264	CDD:304359	82/328 (25%)
		P-loop_NTPase	2343..2613	CDD:304359	77/282 (27%)
		MT	2625..2957	CDD:289543	78/350 (22%)
		AAA_9	2985..3201	CDD:289547	81/222 (36%)
		Dynein_heavy	3342..4066	CDD:281078	175/767 (23%)
DYNC2H1	NP_001073932.1	Stem. /evidence=ECO:0000250	1..1650		250/1247 (20%)
		DHC_N1	162..639	CDD:285571	3/16 (19%)
		DHC_N2	1120..1519	CDD:285579	108/453 (24%)
		P-loop_NTPase	1651..1881	CDD:304359	125/231 (54%)
		AAA 1. /evidence=ECO:0000250	1651..1875		123/225 (55%)
		P-loop_NTPase	<1937..>1988	CDD:304359	22/50 (44%)
		AAA 2. /evidence=ECO:0000250	1938..2161		91/240 (38%)
		AAA_5	1974..2110	CDD:285029	61/145 (42%)
		AAA 3. /evidence=ECO:0000250	2251..2505		70/269 (26%)
		P-loop_NTPase	2285..2494	CDD:304359	64/224 (29%)
		AAA 4. /evidence=ECO:0000250	2617..2863		70/263 (27%)
		P-loop_NTPase	2618..>2829	CDD:304359	64/217 (29%)
		Stalk. /evidence=ECO:0000250	2881..3169		61/303 (20%)
		MT	2897..3229	CDD:289543	78/347 (22%)
		AAA_9	3253..3474	CDD:289547	81/221 (37%)
		Dynein_heavy	3622..4303	CDD:281078	175/780 (22%)
		AAA 6. /evidence=ECO:0000250	3697..3912		64/221 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100025
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810