DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dhc16F and DNAH9

DIOPT Version :9

Sequence 1:	NP_523394.1	Gene:	Dhc16F / 32785	FlyBaseID:	FBgn0283476	Length:	4081	Species:	Drosophila melanogaster
Sequence 2:	XP_011522005.1	Gene:	DNAH9 / 1770	HGNCID:	2953	Length:	4501	Species:	Homo sapiens

Alignment Length:	4178	Identity:	1282/4178 - (30%)
Similarity:	2017/4178 - (48%)	Gaps:	505/4178 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   157 DLNLIINRMRNMPDDS--FVYMDYMLPHDSEYFTPY---------SLR---EVEYKDLNTYEPFY 207
            |..|::.:|.|...|:  .:|..::.......|:|.         .||   |:..:....:..|.
Human   565 DKYLVLIQMFNKDLDAVRMIYSQHVQEEAELGFSPVHKNMPTVAGGLRWAQELRQRIQGPFSNFG 629

  Fly   208 TVTRHGVTFWHCSENFFTPLDQWQQEFKQFLSIIQIRSFSIFRLWKGFKVWEKTIKWRKLNEARD 272
            .:|.      .|.|:  ....:.||:::..||:::.....::..|           .|.::|...
Human   630 RITH------PCMES--AEGKRMQQKYEDMLSLLEKYETRLYEDW-----------CRTVSEKSQ 675

  Fly   273 YLQNNLFIVIPQLAKAILRMRSDIVQLQRLNFVNVSNIENWHPFYFLETHMRIYEQLHKTFTDFR 337
            |          .|::.:|:...:..:: .:|| |...|.......:||..    |..|...|...
Human   676 Y----------NLSQPLLKRDPETKEI-TINF-NPQLISVLKEMSYLEPR----EMKHMPETAAA 724

  Fly   338 EFIAKTIFRACTDAIQARGFYPDDEVNYYPSLKK---------MREAHSFMDRARKRAFCKTLT- 392
            .|.::..:|.....::..       .|:|..:.|         :.|....:| .|.||..:||.
Human   725 MFSSRDFYRQLVANLELM-------ANWYNKVMKTLLEVEFPLVEEELQNID-LRLRAAEETLNW 781

  Fly   393 ------NFLTYCDMMVYQMLYRI--TKKSFEDL--------ATSFEVHDEVGPSEADINKHDRVD 441
                  :::|.....::.:..||  ||.:.|::        ...|:..|  |..|:.::..||.|
Human   782 KTEGICDYVTEITSSIHDLEQRIQKTKDNVEEIQNIMKTWVTPIFKTKD--GKRESLLSLDDRHD 844

  Fly   442 KRIEKQRPQDK--------------------PQS------------------------------- 455
             |:||.....|                    |.|
Human   845 -RMEKYYNLIKESGLKIHALVQENLGLFSADPTSNIWKTYVNSIDNLLLNGFFLAIECSLKYLLE 908

  Fly   456 ---------PFFLAMLRLLPDRIDIEPS-------------EDIIRIIFQRITGLILETVLEIHP 498
                     |.|.|.|.|....:...||             |.:|..|| ||..|    |..:.|
Human   909 NTECKAGLTPIFEAQLSLAIPELVFYPSLESGVKGGFCDIVEGLITSIF-RIPSL----VPRLSP 968

  Fly   499 FTTDPFFTQYTQPSIMGRQEEVLYEGAPDLHYLLRADIRFQYNRKNMFVLIRKAYER-ARLYTQR 562
            ....|.:             :|..:|.|||..:.|..:........:....:..:.: :.||.:.
Human   969 QNGSPHY-------------QVDLDGIPDLANMRRTLMERVQRMMGLCCGYQSTFSQYSYLYVED 1020

  Fly   563 FHQIRENF----------EIDNSTDPTVLNTERDLQILRAYCDRY---CNNVRALDGILEYVFLG 614
            ..::...|          ||::..:..:......|...:...|.|   ...|..|:.|  .||.|
Human  1021 RKEVLGQFLLYGHILTPEEIEDHVEDGIPENPPLLSQFKVQIDSYETLYEEVCRLEPI--KVFDG 1083

  Fly   615 LLKLTQTNFKDTVTPVCSR------------LQNVLATYLPKLAEEETTRLYE-EAQDFHGRICY 666
            .:|:....||.::..:..|            :.:.||.....:.:.|:..|.: |..||.|.:
Human  1084 WMKIDIRPFKASLLNIIKRWSLLFKQHLVDHVTHSLANLDAFIKKSESGLLKKVEKGDFQGLV-- 1146

  Fly   667 EPHETLEIVAHIRFLDKCSTELDGIFDGIDYVHDLLLIIKDFGIPIDDDSKEDYMDTEDYLNRTR 731
                  ||:.|:..:.:..:..|.:|:.:....:||                     :.|.....
Human  1147 ------EIMGHLMAVKERQSNTDEMFEPLKQTIELL---------------------KTYEQELP 1184

  Fly   732 ET----LEEIREKRQDFINRLEDAMQDDIAALK----------------------EDIHEVA--- 767
            ||    |||:.||..: |.::...::..:|.|:                      |..|:.|
Human  1185 ETVFKQLEELPEKWNN-IKKVAITVKQQVAPLQANEVTLLRQRCTAFDAEQQQFWEQFHKEAPFR 1248

  Fly   768 IEALQP-WLLDANSNRLSVTNKLDSMLERLNKCRETADEFLGYQKEFQIDLTMYDEMASGFYDIR 831
            .:::.| .:|||....:   .:::|.:..:::....          |::::..|.::.....::.
Human  1249 FDSIHPHQMLDARHIEI---QQMESTMASISESASL----------FEVNVPDYKQLRQCRKEVC 1300

  Fly   832 MRQNLYRTWSDWEESLAEWIVSDFNTLNVVDMVELNSKTIKNCMQFQKYLPENNIVPVLQKSAEA 896
            ..:.|:.|......|:..|..:.:..:| |:.:||      .|.||.:::..      |.|...|
Human  1301 QLKELWDTIGMVTSSIHAWETTPWRNIN-VEAMEL------ECKQFARHIRN------LDKEVRA 1352

  Fly   897 FK-------------EKLPVIGYLRNPNLRARHWAEIEDLLNRKFFQEKDI----LIQTYEDVHA 944
            :.             ..|..:..|:||.:|.|||.::.......|..::|.    |:|.  .:|.
Human  1353 WDAFTGLESTVWNTLSSLRAVAELQNPAIRERHWRQLMQATGVSFTMDQDTTLAHLLQL--QLHH 1415

  Fly   945 FDDVAIGEALMQISSQATGEVQLENMLKGIETTWKETELSIVPHHDAKDVFILAGTEELQAVLDD 1009
            ::|...|     |..:|..|:.:|..||.::|||...|....| |...:|.:|...|:|..||:|
Human  1416 YEDEVRG-----IVDKAAKEMGMEKTLKELQTTWAGMEFQYEP-HPRTNVPLLCSDEDLIEVLED 1474

  Fly  1010 SNVNINTIAASKFVGPIKSKVDEWINAMDQFAKTFESWMDCQGAWIYLEAIF-ASADIQRQLPHE 1073
            :.|.:..:..||:|.....:|..|...:.........|.:.|..|.:||:|| .|.||:.|||.:
Human  1475 NQVQLQNLVMSKYVAFFLEEVSGWQKKLSTVDAVISIWFEVQRTWTHLESIFTGSEDIRAQLPQD 1539

  Fly  1074 AKMFFTVDKSFKETVRQAKKVALALPTMSSVDVHKVLVENNRLLDLISRGLEAYLEVKRVVFPRF 1138
            :|.|..:|..|||....|:|:...:.|.:...:::.|.:....|.|..:.|..||:.||:.||||
Human  1540 SKRFEGIDIDFKELAYDAQKIPNVVQTTNKPGLYEKLEDIQGRLCLCEKALAEYLDTKRLAFPRF 1604

  Fly  1139 YFLSNDELLEILAQTRIPQAVQPHLRKCFDAIYRLEFGSKEGGDGKMVATNDIVAFLSPEGEKLQ 1203
            ||||:.:||:||:....||.||.||.|.||.:.::.|.....|:    .|...:...|.|.|.:.
Human  1605 YFLSSSDLLDILSNGTAPQQVQRHLSKLFDNMAKMRFQLDASGE----PTKTSLGMYSKEEEYVA 1665

  Fly  1204 FGKGLKARGAVEEWLSKVEEAMFVSCKRYMRFGYQCYPAKEREDWFQDHPNQVVLTVSQVQWAAD 1268
            |.:.....|.||.||:.|...|..:.:..|..|...|..|.||.|..|||.||.||.:|:.|..:
Human  1666 FSEPCDCSGQVEIWLNHVLGHMKATVRHEMTEGVTAYEEKPREQWLFDHPAQVALTCTQIWWTTE 1730

  Fly  1269 I----HRIYEGKERNPLNILEKMAKFEIKCLKDLGALAALTRKNISSLLRKILCALITIDVHAKD 1329
            :    .|:.||.|       ..|..:..|.:..|..|..:....:|...|:.:..:.||||||:|
Human  1731 VGMAFARLEEGYE-------SAMKDYYKKQVAQLKTLITMLIGQLSKGDRQKIMTICTIDVHARD 1788

  Fly  1330 SVRMLIEKEVCKASDFNWLKMLRFYWADETETVYSRMAAANIPYYYEYLGAGGVLVLTPLTDRCY 1394
            .|..:|.::|..|..|.||..||..|.||.:..::.:..|...|.|||||....||:||||||||
Human  1789 VVAKMIAQKVDNAQAFLWLSQLRHRWDDEVKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCY 1853

  Fly  1395 LCLMGAFQMDLGGAPAGPAGTGKTETTKDLAKALAKQCVVFNCSDGLDYKMMGRFFSGLAQCGAW 1459
            :.|..:..:.:.||||||||||||||||||.:||.....|||||:.:|||..|..:.||||.|||
Human  1854 ITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAW 1918

  Fly  1460 CCFDEFNRIDIEVLSVIAQQLITIRTAKAMRVKRFIFEGREIKINRSCCVFITMNPGYAGRTELP 1524
            .||||||||.:|||||:|.|:.:|:.|...:.:.|.|.|.||.:|.|..:|||||||||||||||
Human  1919 GCFDEFNRISVEVLSVVAVQVKSIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNPGYAGRTELP 1983

  Fly  1525 DNLKALFRPISMMVPDYALISEVILYSEGFEDPKILARKMVQMYQLCSQQLSQQNHYDFGMRAVK 1589
            :|||:||||.:|:|||:.||.|::|.:|||.:.:.||||.:.:||||.:.||:|:|||:|:||:|
Human  1984 ENLKSLFRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQDHYDWGLRAIK 2048

  Fly  1590 SVLVMAGALKRASPNQREDITLIAALRDSNIPKFLADDAVLFRGILSDLFPGVELPDSQHPHLEA 1654
            ||||:||:|||..|::.||..|:.:|||.||||.:.||..:|.|::.||||.:::|..:.|:.||
Human  2049 SVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFPALDVPRRRDPNFEA 2113

  Fly  1655 SLRLGLRQKNLQAVPTTIRKCLQLYETMCVRWGVMLVGPTGGGKSVVLHALEFALSHLFENEVQD 1719
            .:|..:....|||....:.|.:||.|.:.||..|.:||..|.|||.||.:|        ....|.
Human  2114 LVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKSQVLRSL--------HKTYQI 2170

  Fly  1720 PNFRPVVIQTMNPKAVTMNELYGYVDLKTLEWQDGLLGLAVRTATTVEDEIHQWIMCDGPVDAVW 1784
            ...|||... :||||||.:||:|.::..|.||:|||....:|....:..:..:||:.||.:|.:|
Human  2171 MKRRPVWTD-LNPKAVTNDELFGIINPATGEWKDGLFSSIMRELANITHDGPKWILLDGDIDPMW 2234

  Fly  1785 IENLNTVLDDNKMLCLANSERIKLTAWIHMLFEVQDLLQASPATVSRCGMVYVDPGDLGWIPLID 1849
            ||:||||:||||:|.||::|||.|...:.:|||:..|..|:||||||.|::|::|.||||.|.:.
Human  2235 IESLNTVMDDNKVLTLASNERIPLNPTMKLLFEISHLRTATPATVSRAGILYINPADLGWNPPVS 2299

  Fly  1850 TWREVDMKHKLPAPLAEFCYQLFVGYFDKALKIERKRAVYTIHQVLGSKVRLCCELNSAQFEAVK 1914
            :|.|   |.::....|.... ||..|....|...|.|....|.....|.|::.|.|...   .:.
Human  2300 SWIE---KREIQTERANLTI-LFDKYLPTCLDTLRTRFKKIIPIPEQSMVQMVCHLLEC---LLT 2357

  Fly  1915 WSAMSEEQGKELVTKIFAWAVLWAIASNLKDAEKVSFEEQWSK-AIAQHPNMTLPN-FTLWNYRI 1977
            ...:..:..||:....|.:|.:||....:...:.|.:..::|| .:.:...:..|: .|:::|.|
Human  2358 TEDIPADCPKEIYEHYFVFAAIWAFGGAMVQDQLVDYRAEFSKWWLTEFKTVKFPSQGTIFDYYI 2422

  Fly  1978 DLEKMDWGSWIDIMAKFVFDPETSYYDMQVPTVDTTKYGYVSDLLFKRGMPVMVTGDTGVGKTVL 2042
            |.|...:..|..::.:|.||||.......|.|.:|.:..|..:.|..|..|||:.|..|.||:||
Human  2423 DPETKKFEPWSKLVPQFEFDPEMPLQACLVHTSETIRVCYFMERLMARQRPVMLVGTAGTGKSVL 2487

  Fly  2043 AISCMKRLSQGNVIPVILNFSAQTSSNRTQEMIEGPLEKRKKTQLGAPVGKTVIVFIDDVNMPKL 2107
            ..:.:..|.....:...:.|:..|:|...|.::|.||||:.....|.|..|.:|.||||:|||::
Human  2488 VGAKLASLDPEAYLVKNVPFNYYTTSAMLQAVLEKPLEKKAGRNYGPPGNKKLIYFIDDMNMPEV 2552

  Fly  2108 DTYGASPAIELLRQFLDFKGFYDREKLYWKEILDVVLGCACAPPGGGRNPLTPRFVRHFALFSLP 2172
            |.||......::||.||:..:|||.||..|||.:|.. .:|..|..|...:.||..|||::|.|.
Human  2553 DAYGTVQPHTIIRQHLDYGHWYDRSKLSLKEITNVQY-VSCMNPTAGSFTINPRLQRHFSVFVLS 2616

  Fly  2173 KPNEETLTQIFNGILRGFLQ--TFSSAVRALSEPMVNACVDVYMRVATVMLPTPDKSHYIFNLRD 2235
            .|..:.|:.|::.||...|:  .|.::::....|:::..:..:.::||..|||..|.||||||||
Human  2617 FPGADALSSIYSIILTQHLKLGNFPASLQKSIPPLIDLALAFHQKIATTFLPTGIKFHYIFNLRD 2681

  Fly  2236 LSKCIQGILQASNLHYNQENQILRLFYHETTRVFHDRLINIEDKNIFKALMKEV---CMDHFNRP 2297
            .:...||||.:|.........::||:.||:.||:.|:::..:|.::|..:..||   ..|....|
Human  2682 FANIFQGILFSSVECVKSTWDLIRLYLHESNRVYRDKMVEEKDFDLFDKIQTEVLKKTFDDIEDP 2746

  Fly  2298 VINDNEPPILFGDFM-VFGKPKNERIYDEIRDHTKLESVLNDYIADYNSVAVGKQMKLILFQDAM 2361
            | ...:.|.|:..|. ..|:||    |..::....|...|.:.:.::|.  |...|.|:||:|||
Human  2747 V-EQTQSPNLYCHFANGIGEPK----YMPVQSWELLTQTLVEALENHNE--VNTVMDLVLFEDAM 2804

  Fly  2362 EHTVRLARLLRSDRGNGLLVGVAGMGKQSLTRLASHVNEYNCWQIEMRRNYDLNAFHEDLRVLYR 2426
            .|...:.|:|.|.|||.|||||.|.|||||||||:.::..:.:||.:|:.|.:..|..||..|..
Human  2805 RHVCHINRILESPRGNALLVGVGGSGKQSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLCL 2869

  Fly  2427 IAGIDNQPVTFLLIDSQIVEEEFLEDINNILNSGEVPNLFEGDEFEKIILDARDGCNENRKDDPC 2491
            .||:.|....||:.|:|:.:|.||..||::|.|||:|:|:..||.|.||.:.|:........|
Human  2870 KAGVKNLNTVFLMTDAQVADERFLVLINDLLASGEIPDLYSDDEVENIISNVRNEVKSQGLVD-- 2932

  Fly  2492 TRDDIYKFFINRVRNNLHVVMSMSPVGDAFRRRCRMFPSLVNCTTIDWFTSWPTEALYSVALGLL 2556
            .|::.:||||:|:|..|.|.:..||||:..|.|.|.||::||||.|.||..||.:||.||:|..|
Human  2933 NRENCWKFFIDRIRRQLKVTLCFSPVGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRFL 2997

  Fly  2557 TK---IAPKMEDRISLASTTVFMHKTVEDASVKFYKEMKRHYYTTPSSYLELLKLYQNLLKIKNM 2618
            ..   |.|.::.  |::....|:|.:|...|..:....:|:.||||.|:||.::|||:||.....
Human  2998 QNTEGIEPTVKQ--SISKFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRK 3060

  Fly  2619 EIIAKRKRIANGLNKLLETNEVIAVMGKELEVMVPQLDEKSAMMKSLV-------DNLTKETKQA 2676
            |:..|.:|:.|||.||..|:..:..:..:|.....:|.:|:.....|:       |.:::|...|
Human  3061 ELKCKTERLENGLLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSREKAMA 3125

  Fly  2677 DAVKQSVLEDEMNAKEKAAVAQAISEDAGKDLEIAMPALREAEEALKGLTKADINELKSFTTPPA 2741
            |..:|.|....:..|:|       .:|..:||..|.|||..|:.||..|.|.::.|||||.:||.
Human  3126 DEEEQKVAVIMLEVKQK-------QKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPPL 3183

  Fly  2742 LVQFCMEAVCILL---GVKP---TWASAKAIMADIN-FIKRLFEYDKEHMKEDTLKKVKKYIDHK 2799
            .|.....||.:|:   |..|   :|.:||..||.:: |:..|..::||::.|:.||.::.|:...
Human  3184 AVSNVSAAVMVLMAPRGRVPKDRSWKAAKVTMAKVDGFLDSLINFNKENIHENCLKAIRPYLQDP 3248

  Fly  2800 DFVPAKFEKVSKVAKSMSMWVISMDKFSKVYKVVEPKIKRKEAAEAELKEVMTVLRQKQKELAAV 2864
            :|.|......|..|..:..|||::.:|.:|:..||||.:....|.|:|...       |::|||:
Human  3249 EFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADLTAA-------QEKLAAI 3306

  Fly  2865 EAKIQGLRDSLEEKQREFQ-------VIQDNVDLTYGRINRAGRLTSALSDEQVRWRETVKSLTG 2922
            :|||..|.::|.:....|:       ..|...::|...|:.|.||...|:.|.|||.:.|::...
Human  3307 KAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAVTISLANRLVGGLASENVRWADAVQNFKQ 3371

  Fly  2923 DLACVPGDVLVAAACVAYLGAFSHEYRRD-MSALWVSKCREHK--IPSSPEFNLLKVLGDPYEMR 2984
            ....:.||:|:..|.::|||.|:.:||:. :...|.....:.|  ||.:|..:.|::|.|..::.
Human  3372 QERTLCGDILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLKTPIPVTPALDPLRMLMDDADVA 3436

  Fly  2985 QWNVDGLPKDNISIENGIYATRALRWALMIDPQEQANRWIRNMERANNLQVIKMTDSTMMRVLEN 3049
            .|..:|||.|.:|:||........||.||:|||.|..:||:| :...:|:|.::.....::::|.
Human  3437 AWQNEGLPADRMSVENATILINCERWPLMVDPQLQGIKWIKN-KYGEDLRVTQIGQKGYLQIIEQ 3500

  Fly  3050 AVRQGYPVLLEEINETIDPSLRPILQRETYRFEGRTYLKLGDMVIDYDDNFKLYMTTKLPNPHYL 3114
            |:..|..||:|.:.|:|||.|.|:|.||..: :|| ::|:||...:|:..|:|.:.|||.||||.
Human  3501 ALEAGAVVLIENLEESIDPVLGPLLGREVIK-KGR-FIKIGDKECEYNPKFRLILHTKLANPHYQ 3563

  Fly  3115 PEVCINVTLVNFLVTESGLEDQLLADIVAIELPAMEIQRNDLVVKINSDKQQLLALEDKVLKLLF 3179
            ||:....||:||.||..||||||||.:|::|.|.:|..::||..:.|..|..|..|||.:|..|.
Human  3564 PELQAQATLINFTVTRDGLEDQLLAAVVSMERPDLEQLKSDLTKQQNGFKITLKTLEDSLLSRLS 3628

  Fly  3180 NSEGNILDDEELVETLNDAKETSLIIAARLIDTEETEKVITASRERYRILASRGAILYFVVAGLA 3244
            ::.||.|.:..|||.|...|:|:..:..::.:.:.||..|..:||.||..|:|.::|||::..|:
Human  3629 SASGNFLGETVLVENLEITKQTAAEVEKKVQEAKVTEVKINEAREHYRPAAARASLLYFIMNDLS 3693

  Fly  3245 EIDPMYQYSLKYFTQVFCNVLRLDHPPQSVEVRISTLMTDELRAIFDNISRGLFENHKIIFSFLL 3309
            :|.||||:|||.|:.||...:....|.:|:..|::.|:.....:::....|||||..|:.:...|
Human  3694 KIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFECDKLTYLAQL 3758

  Fly  3310 ALSVERQEGRVTEEEFLFLSRGPVGNIRTKIQPAKIKMSQIEWDSCIFLEDNFSSF--FSGLTDE 3372
            ...:......|...|..||.|.||..  ....|.:. :|...|.:...|    ||.  ||.|..:
Human  3759 TFQILLMNREVNAVELDFLLRSPVQT--GTASPVEF-LSHQAWGAVKVL----SSMEEFSNLDRD 3816

  Fly  3373 LDKPFFIQMQENKEVFDFAQTNQPPTDK----WNKRLRVFHKLMFISAFRKPRFLLNVVCYLQST 3433
            ::       ...|....|.::..|..:|    | |......:|..:.|.|..|....:..:::..
Human  3817 IE-------GSAKSWKKFVESECPEKEKLPQEW-KNKTALQRLCMLRAMRPDRMTYALRDFVEEK 3873

  Fly  3434 VGKYFTEASGGTQLSSVYLDTSAVTPLIFVLSTGSDPMSGFLKFTTQMQFT---DKYYSISLGQG 3495
            :|..:. .......::.:.::...||:.|:||.|.||:........::.:|   ..::::|||||
Human  3874 LGSKYV-VGRALDFATSFEESGPATPMFFILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQG 3937

  Fly  3496 QGPLAENLIEKSLRLGHWVFLQNCHLATSFMQTLETIVRNLTLGITKAHVDFRLYLSSMPIQT-- 3558
            |..:||..::.:.:.||||.|||.||...::.|||   :.|......:|.:||:::|:.|..:
Human  3938 QEVVAEAALDLAAKKGHWVILQNIHLVAKWLSTLE---KKLEEHSENSHPEFRVFMSAEPAPSPE 3999

  Fly  3559 ---FPISVLQNSVKITNEPPKGIKANVFGALTDLKQDFFEQHIQNGNWRAIVFGLCMFHAVLLER 3620
               .|..:|:||:|||||||.|:.||:..||.:..||..|...:...:::|:|.||.||||:.||
Human  4000 GHIIPQGILENSIKITNEPPTGMHANLHKALDNFTQDTLEMCSRETEFKSILFALCYFHAVVAER 4064

  Fly  3621 RKFGPLGWNITYEFSESDRECGLKTLDFFIDREVLDEIPWEAILYINGDITWGGRVTDYWDLRCL 3685
            |||||.|||.:|.|:..|....:..|..|::...  ::|::.:.|:.|:|.:||.:||.||.|..
Human  4065 RKFGPQGWNRSYPFNTGDLTISVNVLYNFLEANA--KVPYDDLRYLFGEIMYGGHITDDWDRRLC 4127

  Fly  3686 RTILTIFSSKRIIQPDYKYCRGDSYYRDPRKKTLTEYSAYVQGFPVLEDPEIFGMNQNANIVFQT 3750
            ||.|..|....:::.:.....|   :..|.......|..|:......|.|.::|::.||.|.|.|
Human  4128 RTYLGEFIRPEMLEGELSLAPG---FPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNAEIGFLT 4189

  Fly  3751 KETAFFINTLLLGQPR-SAADEGQAMENE--------IAQQTIARIQKALATKIKREPIHDTLSV 3806
            :.:.....|:|..||| |.|.:|.....|        ....||....|||..:| .|.:.|..::
Human  4190 QTSEKLFRTVLELQPRDSQARDGAGATREEKLFSWRWHCVLTIQGKVKALLEEI-LERVTDEFNI 4253

  Fly  3807 LDAKGQVPSLT---IVLVQEIDRFNIALGIIHDSLVNLSKAIKGLVVMSEELENVFKALLSNQVP 3868
            .:...:|...|   :|..||..|.||....|..||..|...:||.:.|:..:||:..||..:.||
Human  4254 PELMAKVEERTPYIVVAFQECGRMNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFDMVP 4318

  Fly  3869 ASWAKRSFLSIKPLPSYISDFQRRIDFIQQW-AENGAPRSYWISGFFFPQSFLTGVLQTYARRRV 3932
            .|||:|::.|...|.::..|...||..::.| .:...|.:.|::|||.||||||.::|:.||:..
Human  4319 ESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIMQSTARKNE 4383

  Fly  3933 LPIDSLKIDFDVFERELVQQDFFEMHTNNMSDQKLYGNLPECTDAIINVHGIFIEAARWDLSKGG 3997
            .|:|.:.:..|:.::.  :::|               ..|....|.|  ||:|:|.|.||...|.
Human  4384 WPLDQMALQCDMTKKN--REEF---------------RSPPREGAYI--HGLFMEGACWDTQAGI 4429

  Fly  3998 LCDANFGELFSRMPVVRFK-------PCLEISPTVRYEAPLYKTQQRSGVLSTTGHSTNFILAVL 4055
            :.:|...:|...|||:..|       .|..:     |..|:|||.||         ...::....
Human  4430 ITEAKLKDLTPPMPVMFIKAIPADKQDCRSV-----YSCPVYKTSQR---------GPTYVWTFN 4480

  Fly  4056 LRSHNDPEFWIMRGTALV 4073
            |::..:|..|::.|.||:
Human  4481 LKTKENPSKWVLAGVALL 4498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhc16F	NP_523394.1	DHC_N2	829..1234	CDD:285579	119/422 (28%)
		P-loop_NTPase	1373..1603	CDD:304359	137/229 (60%)
		P-loop_NTPase	1687..1832	CDD:304359	63/144 (44%)
		P-loop_NTPase	1994..2264	CDD:304359	96/271 (35%)
		P-loop_NTPase	2343..2613	CDD:304359	115/272 (42%)
		MT	2625..2957	CDD:289543	105/353 (30%)
		AAA_9	2985..3201	CDD:289547	89/215 (41%)
		Dynein_heavy	3342..4066	CDD:281078	217/757 (29%)
DNAH9	XP_011522005.1	DHC_N1	212..789	CDD:285571	46/266 (17%)
		DHC_N2	1295..1699	CDD:285579	120/428 (28%)
		P-loop_NTPase	1832..2062	CDD:304359	137/229 (60%)
		P-loop_NTPase	2146..2281	CDD:304359	62/143 (43%)
		AAA_7	2439..2710	CDD:289541	96/271 (35%)
		AAA_8	2788..3055	CDD:289546	115/272 (42%)
		MT	3067..3410	CDD:289543	106/356 (30%)
		AAA_9	3438..3650	CDD:289547	89/214 (42%)
		Dynein_heavy	3790..4491	CDD:281078	216/756 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5245
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1492at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100025
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.720