DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dhc16F and DNAH6

DIOPT Version :9

Sequence 1:	NP_523394.1	Gene:	Dhc16F / 32785	FlyBaseID:	FBgn0283476	Length:	4081	Species:	Drosophila melanogaster
Sequence 2:	NP_001361.1	Gene:	DNAH6 / 1768	HGNCID:	2951	Length:	4158	Species:	Homo sapiens

Alignment Length:	4201	Identity:	1890/4201 - (44%)
Similarity:	2631/4201 - (62%)	Gaps:	214/4201 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 IKGKEKEKERKKDEDDDGSR--------KARERGRSRRQSAGGGDHSVDMGFKRVTGEDRP-SSM 75
            ||.|::.......|::..::        ||:|:.|.|:|.              :..|..| ..:
Human    30 IKAKQRVSYVTSTENESDTQILTFRHITKAQEKTRKRQQP--------------IKLEPLPVLKV 80

  Fly    76 SMDRLDSDFAAFTDRASDANDGSITGPADGNGKKAQTGGKQ--------KRASKHR-----LNFS 127
            ..|....::....:|......|.|..|.....|...|...|        |:...||     .:.|
Human    81 YQDHKQPEYIHEQNRFQLMTAGIIKRPVSIAKKSFATSSTQFLEHQDAVKKMQIHRPYVEVFSPS 145

  Fly   128 TSKSAGSGTGNK----SRSASTTKIT------TGASLIPDLNLIINRMRNMPDDSFVYMDYMLPH 182
            ..|...:|.|.:    :||::..|.|      ...:.|.|...||..:|......|:||...:|.
Human   146 PPKLPHTGIGKRGLFGTRSSAYPKYTFHDREEVVKANIRDPLQIIKIIRENEHLGFLYMIPAVPR 210

  Fly   183 DSEYFTPYSLREVEYKDLNTYEPFYTVTRHGVTFWHCSENFFTPLDQWQQEFKQFLSIIQIRSFS 247
            .|..:..|:|:.|.|:::|..: :||:::..||..:..:..|..:|:|:||:.....:.:|..||
Human   211 SSIEYDTYNLKVVSYENINKND-YYTISQRAVTHIYNEDIEFIEIDRWEQEYLYHRELTKIPIFS 274

  Fly   248 IFRLWKGFKVWEKTIKWRKLNEARDYLQNNLFIVIPQLAKAILRMRSDIVQLQRLNFVNVSNIEN 312
            :||.||.|.||.|.::.:|:...:..||.|||||.|.|..|:|::..   ....|:|:.:..||.
Human   275 LFRKWKAFSVWRKNVRSKKITGCQKSLQKNLFIVNPHLRPALLKINE---LCYHLSFMGLCYIEK 336

  Fly   313 WHPFYFLETH----MRIYEQLHKTFTDFREFIAKTIFRACTDAIQARGFYPDD------------ 361
            .|.:...|..    :|:.| :.:...:||......:.|||..|::|.||.|||
Human   337 CHTYTLQEFKAAQVIRLAE-VTERLGEFRNEAKYVVRRACRFALRAAGFVPDDCAFGPFEDYHKV 400

  Fly   362 -----------EVNYYPSLKKMREAHSFMDRARKRAFCKTLTNFLTYCDMMVYQMLYRITKKSFE 415
                       |:..|...:||    ::.::|.||.:|..||.|:...|.::...::.:|..:..
Human   401 QSSGSFINTPHELPTYGDSEKM----TYTEQASKRHYCMRLTCFIRLNDYLIENTMHILTVNAVN 461

  Fly   416 DLATSFEVHDEVGPSEADI-------NKHDRVDKR----IEKQRPQDKPQSPFFLAMLRLLPDRI 469
            .|........:..|| ||:       .|.:..||:    :|||. :|:...|.||..|.|....:
Human   462 SLLNHLTDKLKRTPS-ADVIQKWITEEKPEVPDKKGTLMVEKQE-EDESLIPMFLTELMLTVQSL 524

  Fly   470 DIEPS-EDIIRIIFQRITGLI---LETVLEIHPFTTDPFFTQYTQPSIMGRQEEVLYEGAPDLHY 530
            ..||| ||.:    ..|.|.:   ..|||.:.....|.:|..:|.|.|..:.|.......|.|..
Human   525 LFEPSLEDFL----DGILGAVNHCQNTVLSVPNLVPDSYFDAFTSPYINNKLEGKTCGTGPSLAA 585

  Fly   531 LLRADIRFQYNRKNMFVLIRKAYERARLYTQRFHQIRENFEIDNSTDPTVLN-TERDLQILRAYC 594
            :...|..|......:...|:.|:|.||:|...|.:.:..|:.:.|.|...|. .|.|:.......
Human   586 VFEDDKNFHTIISQIKETIQAAFESARIYAATFEKFQIFFKENESLDLQALKLQEPDINFFSEQL 650

  Fly   595 DRYCNNVRALDGILEYVFLGLLKLTQTNFKDTVTPVCSRLQNVLATYLPKLAEEETTRLYEEAQD 659
            ::|....:....:.....:|||.:.....::.:.|...|...||...||:.::::...:..||||
Human   651 EKYHKQHKDAVALRPTRNVGLLLIDTRLLREKLIPSPLRCLEVLNFMLPRQSKKKVDAIIFEAQD 715

  Fly   660 FHGRICYEPHETLEIVAHIRFLDKCSTELDGIFDGIDYVHDLLLIIKDFGIPIDDDSKEDYMDTE 724
            ...::.:.|..|.|.|..:.|||:....::.:.|..:.|..:..:::.:.:|...:....:...:
Human   716 AEYKLEFVPTTTTEYVHSLLFLDEIQERIESLEDEGNIVTQMYKLMEQYQVPTPPEDFAVFATMK 780

  Fly   725 DYLNRTRETLEEIREKRQDFINRLEDAMQDDIAALKEDIHEVAIEALQPWLLDANSN----RLSV 785
            ..:...|..:::....|:..|.:....:..|:..|..:::||.::|..|.:||.:::    || :
Human   781 PSIVAVRNAIDKSVGDRESSIKQFCVHLGSDLEELNNEVNEVKLQAQDPQILDISADQDKIRL-I 844

  Fly   786 TNKLDSMLERLNKCRETADEFLGYQKEFQIDLTMYDEMASGFYDIRMRQNLYRTWSDWEESLAEW 850
            .|.|.|:|..|.|   .|.::..|||.|:::::.::.:.....:::::|.|:.::|:|::...||
Human   845 LNNLQSVLADLQK---RAFQYKSYQKNFKVEVSKFEALEEVSAELKLKQLLWDSFSEWDKLQQEW 906

  Fly   851 IVSDFNTLNVVDMVELN---SKTIKNCMQFQKYLPENNIVPVLQKSAEAFKEKLPVIGYLRNPNL 912
            :.|.|:.|   |...||   ||..|...|.:|.||.|::||.|:...|..|||||||..||||.|
Human   907 LKSKFDCL---DPEVLNGQVSKYAKFVTQLEKGLPPNSVVPQLKYKVEKMKEKLPVIIDLRNPTL 968

  Fly   913 RARHWAEIEDLLNRKFFQ-EKDILIQTYEDVHAFDDVAIGEALMQISSQATGEVQLENMLKGIET 976
            :|||||.||..::..... |..:.::....:|.||   .|:.:..||.||:||..||.:||.:|.
Human   969 KARHWAAIEQTVDATLVDAEIPLTLERLSQLHVFD---FGQEIQDISGQASGEAALEAILKKVED 1030

  Fly   977 TWKETELSIVPHHDAKDVFILAGTEELQAVLDDSNVNINTIAASKFVGPIKSKVDEWINAMDQFA 1041
            :||.||..|:||.|:||||||.||:::|.:||||.:|:.|:|:|:::||:|::||||...:..|.
Human  1031 SWKTTEFVILPHRDSKDVFILGGTDDIQVLLDDSTINVATLASSRYLGPLKTRVDEWQKQLALFN 1095

  Fly  1042 KTFESWMDCQGAWIYLEAIFASADIQRQLPHEAKMFFTVDKSFKETVRQAKKVALALPTMSSVDV 1106
            :|.|.|:.||..|:|||:||.:.|||||||.|||||..||||:||.:|:..::..||...:...:
Human  1096 QTLEEWLTCQRNWLYLESIFNAPDIQRQLPAEAKMFLQVDKSWKEIMRKVNRLPNALRAATQPGL 1160

  Fly  1107 HKVLVENNRLLDLISRGLEAYLEVKRVVFPRFYFLSNDELLEILAQTRIPQAVQPHLRKCFDAIY 1171
            .:....||.|||.|.:.||||||.|||:||||||||||||||||||||.|||||||||||||:|.
Human  1161 LETFQNNNALLDQIQKCLEAYLESKRVIFPRFYFLSNDELLEILAQTRNPQAVQPHLRKCFDSIS 1225

  Fly  1172 RLEFGSKEGGDGKM---------VATNDIVAFLSPEGEKLQFGKGLKARGAVEEWLSKVEEAMFV 1227
            :|||......:||:         |.||||:|.||||||::..||||||||.|||||.|||||||.
Human  1226 KLEFALMPPAEGKIPGIDGEPEKVYTNDILAMLSPEGERVSLGKGLKARGNVEEWLGKVEEAMFT 1290

  Fly  1228 SCKRYMRFGYQCYPAKEREDW-FQDHPNQVVLTVSQVQWAADIHRIYEGKERNPLNILEKMAKFE 1291
            |.:|..:.....|..|.|.|| ...||:||:|||||:.|..|:....|.:..|.:..|:   .||
Human  1291 SLRRLCKAAIADYQGKLRTDWVVAGHPSQVILTVSQIMWCRDLTECLETEHSNHIQALK---NFE 1352

  Fly  1292 IKCLKDLGALAALTRKNISSLLRKILCALITIDVHAKDSVRMLIEKEVCKASDFNWLKMLRFYWA 1356
            ....:.|.||||:.:.::..|.|.||.|||||||||:|.|..|::.:|.....|:|.:.||:||.
Human  1353 KVNFERLNALAAIVQGSLPKLHRNILTALITIDVHARDIVTELVQSKVETVESFDWQRQLRYYWD 1417

  Fly  1357 DETETVYSRMAAANIPYYYEYLGAGGVLVLTPLTDRCYLCLMGAFQMDLGGAPAGPAGTGKTETT 1421
            .:.:...:|||.:...|.||||||...||:||||||||||||||.|:||||||||||||||||||
Human  1418 IDLDNCVARMALSQYTYGYEYLGACPRLVITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETT 1482

  Fly  1422 KDLAKALAKQCVVFNCSDGLDYKMMGRFFSGLAQCGAWCCFDEFNRIDIEVLSVIAQQLITIRTA 1486
            ||||||||.|||||||||||||||||||||||||.||||||||||||||||||||||||||||.|
Human  1483 KDLAKALAIQCVVFNCSDGLDYKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQLITIRNA 1547

  Fly  1487 KAMRVKRFIFEGREIKINRSCCVFITMNPGYAGRTELPDNLKALFRPISMMVPDYALISEVILYS 1551
            ||.::.||:|||||||:..:|..||||||||||||||||||||||||.:||||:||||:||||||
Human  1548 KAAKLSRFMFEGREIKLVMTCAAFITMNPGYAGRTELPDNLKALFRPFAMMVPNYALIAEVILYS 1612

  Fly  1552 EGFEDPKILARKMVQMYQLCSQQLSQQNHYDFGMRAVKSVLVMAGALKRASPNQREDITLIAALR 1616
            ||||..|||||||.|||:|||:|||||:|||||||||||||||||:|||.:|:..||:.||.||:
Human  1613 EGFESSKILARKMTQMYKLCSEQLSQQDHYDFGMRAVKSVLVMAGSLKRENPDLNEDVVLIRALQ 1677

  Fly  1617 DSNIPKFLADDAVLFRGILSDLFPGVELPDSQHPHLEASLRLGLRQKNLQAVPTTIRKCLQLYET 1681
            |||:||||.|||:||.||:|||||||::|:..:..|::::...:.::|||.....:||.:|.|||
Human  1678 DSNLPKFLTDDALLFSGIISDLFPGVQIPEHDYGILQSTIVDVMNRQNLQPEMCMVRKVIQFYET 1742

  Fly  1682 MCVRWGVMLVGPTGGGKSVVLHALEFALSHLFENEVQDPNFRPVVIQTMNPKAVTMNELYGYVDL 1746
            |.||.||||||||||||:.|...|...|.:|.:..:::..::.|....:|||::||.||||.|:.
Human  1743 MLVRHGVMLVGPTGGGKTTVYRILAETLGNLQKLGIENSFYQAVKTYVLNPKSITMGELYGEVNN 1807

  Fly  1747 KTLEWQDGLLGLAVRTATTVEDEIHQWIMCDGPVDAVWIENLNTVLDDNKMLCLANSERIKLTAW 1811
            .||||:|||:.|:||.|.....|.|:||:.||||||:||||:|||||||||||||||||||||..
Human  1808 LTLEWKDGLMALSVRAAVNDTSEDHKWIISDGPVDALWIENMNTVLDDNKMLCLANSERIKLTPQ 1872

  Fly  1812 IHMLFEVQDLLQASPATVSRCGMVYVDPGDLGWIPLIDTWREVDMKHKLPAPLAEFCYQLFVGYF 1876
            ||||||||||..||||||||||||:|||.:|.|:|.:.||.: .:..||.....|:...||..|.
Human  1873 IHMLFEVQDLRVASPATVSRCGMVFVDPEELKWMPYVKTWMK-GISKKLTEETQEYILNLFQRYV 1936

  Fly  1877 DKALKIERKRAVYTIHQVLGSKV-RLCCELNSAQF--EAVKWSAMSEEQGKELVTKIFAWAVLWA 1938
            |:.|....|:....|.||..||| .|||.|.|...  :.|. .||.:.:...::.:.|.:..||:
Human  1937 DEGLHFINKKCSQAIPQVDISKVTTLCCLLESLILGKDGVN-LAMEQTKLNTILCQTFVFCYLWS 2000

  Fly  1939 IASNLKDAEKVSFEEQWSKAIAQHPNMTLPNF-TLWNYRIDLEKMDWGSWIDIMAKFVFDPETSY 2002
            :..||.:....||:.........:|:..|||. .||:..:|.:......|..|:..|.::.:..:
Human  2001 LGGNLTENYYDSFDTFIRTQFDDNPDARLPNSGDLWSIHMDFDTKRLDPWERIIPTFKYNRDVPF 2065

  Fly  2003 YDMQVPTVDTTKYGYVSDLLFKRGMPVMVTGDTGVGKTVLAISCMKRLSQ-GNVIPVILNFSAQT 2066
            ::|.|||.||.:|||:.:.|......|:.||.|||||:|:|...:.::.: ...:||.|||||||
Human  2066 FEMLVPTTDTVRYGYLMEKLLAVKHSVLFTGITGVGKSVIAKGLLNKIQESAGYVPVYLNFSAQT 2130

  Fly  2067 SSNRTQEMIEGPLEKRKKTQLGAPVGKTVIVFIDDVNMPKLDTYGASPAIELLRQFLDFKGFYDR 2131
            ||.||||:||..||:::|..||||..|.:::|:||:|||:||.||:.|.||||||:.||.|||||
Human  2131 SSARTQEIIESKLERKRKNILGAPGNKRIVIFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYDR 2195

  Fly  2132 EKLYWKEILDVVLGCACAPPGGGRNPLTPRFVRHFALFSLPKPNEETLTQIFNGILRGFLQTFSS 2196
            .||:||||.||.:..|||||||||||:||||:|||::..||.|:|.:|.|||..||.|||..|..
Human  2196 NKLFWKEIQDVTIISACAPPGGGRNPVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNGFLSDFPP 2260

  Fly  2197 AVRALSEPMVNACVDVYMRVATVMLPTPDKSHYIFNLRDLSKCIQGILQASNLHYNQENQILRLF 2261
            ||:..:..:|.|.|::|.:::..:||||.||||:|||||||||:|||||.......:|.||.|||
Human  2261 AVKQTASSIVEASVEIYNKMSVDLLPTPAKSHYVFNLRDLSKCVQGILQCDPGTIREEIQIFRLF 2325

  Fly  2262 YHETTRVFHDRLINIEDKNIFKALMKEVCMDHFNRPVINDNE----PPILFGDFMVFGKPKNERI 2322
            .||..|||||||||.|||:.|..::.|:...||.  :..|.|    .||:||||:.||..|.:||
Human  2326 CHECQRVFHDRLINNEDKHYFHVILTEMANKHFG--IAIDLEYFLNKPIIFGDFIKFGADKADRI 2388

  Fly  2323 YDEIRDHTKLESVLNDYIADYNSVAVGKQMKLILFQDAMEHTVRLARLLRSDRGNGLLVGVAGMG 2387
            ||::.|..|..:||.||:.||| :...|::||:.||||:||..|:||::|.:|||.|||||.|.|
Human  2389 YDDMPDIEKTANVLQDYLDDYN-LTNPKEVKLVFFQDAIEHVSRIARMIRQERGNALLVGVGGTG 2452

  Fly  2388 KQSLTRLASHVNEYNCWQIEMRRNYDLNAFHEDLRVLYRIAGIDNQPVTFLLIDSQIVEEEFLED 2452
            ||||||||:|:..|.|.|||:.|.|:.::||||||.||::||::::.:.||..|:|||.||||||
Human  2453 KQSLTRLAAHICGYKCLQIELSRGYNYDSFHEDLRKLYKMAGVEDKNMVFLFTDTQIVVEEFLED 2517

  Fly  2453 INNILNSGEVPNLFEGDEFEKIILDARD-----GCNENRKDDPCTRDDIYKFFINRVRNNLHVVM 2512
            |||||||||||||||.||.|:::...|.     |.:|.      .||:::::||::||..||:|:
Human  2518 INNILNSGEVPNLFEKDELEQVLAATRPRAKEVGISEG------NRDEVFQYFISKVRQKLHIVL 2576

  Fly  2513 SMSPVGDAFRRRCRMFPSLVNCTTIDWFTSWPTEALYSVALGLLTKI-APKMEDRISLASTTVFM 2576
            .|||||:|||.|||||||||||.|||||..||.|||.||:....::: |...|.:..|....|.:
Human  2577 CMSPVGEAFRSRCRMFPSLVNCCTIDWFVQWPREALLSVSKTFFSQVDAGNEELKEKLPLMCVNV 2641

  Fly  2577 HKTVEDASVKFYKEMKRHYYTTPSSYLELLKLYQNLLKIKNMEIIAKRKRIANGLNKLLETNEVI 2641
            |.:|...:.::|.|::|.|||||:|||||:.||.::|..|..:||:.|.|:.|||.||||||.::
Human  2642 HLSVSSMAERYYNELRRRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTKLLETNILV 2706

  Fly  2642 AVMGKELEVMVPQLDEKSAMMKSLVDNLTKETKQADAVKQSVLEDEMNAKEKAAVAQAISEDAGK 2706
            ..|..:|..:.|.|..||..:::|::.|..:.:.||.|:.:|.|||..||.||...|||::||.:
Human  2707 DKMKLDLSALEPVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKVKAEETQAIADDAQR 2771

  Fly  2707 DLEIAMPALREAEEALKGLTKADINELKSFTTPPALVQFCMEAVCILLGVKPTWASAKAIMADIN 2771
            ||:.|:|||..|.:||..|.||||:|::.||.||.||...|||:.|||..||.|.|||.::.|.|
Human  2772 DLDEALPALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISILLNAKPDWPSAKQLLGDSN 2836

  Fly  2772 FIKRLFEYDKEHMKEDTLKKVKKYIDHKDFVPAKFEKVSKVAKSMSMWVISMDKFSKVYKVVEPK 2836
            |:|||.|||||::|...|.|::|||::.||||.|.|||||..|||.|||.:||.:|:|.||||||
Human  2837 FLKRLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACKSMCMWVRAMDLYSRVVKVVEPK 2901

  Fly  2837 IKRKEAAEAELKEVMTVLRQKQKELAAVEAKIQGLRDSLEEKQREFQVIQDNVDLTYGRINRAGR 2901
            .::..||:|||...|..||:||..|..||.:||.|:|..::...|.:.:...:.||..|:.|||:
Human  2902 RQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEYDKGVNEKESLAKTMALTKARLVRAGK 2966

  Fly  2902 LTSALSDEQVRWRETVKSLTGDLACVPGDVLVAAACVAYLGAFSHEYRRDMSALWVSKCREHKIP 2966
            ||:||.||||||.|:::....:::.:.|:|.:|||||||.|||:.:||:.:...|:..|:..:||
Human  2967 LTAALEDEQVRWEESIQKFEEEISNITGNVFIAAACVAYYGAFTAQYRQSLIECWIQDCQSLEIP 3031

  Fly  2967 SSPEFNLLKVLGDPYEMRQWNVDGLPKDNISIENGIYATRALRWALMIDPQEQANRWIRNMERAN 3031
            ..|.|:|:.:||||||:||||.||||:|.||.||||..|:..||.||||||:||||||||.|..:
Human  3032 IDPSFSLINILGDPYEIRQWNTDGLPRDLISTENGILVTQGRRWPLMIDPQDQANRWIRNKESKS 3096

  Fly  3032 NLQVIKMTDSTMMRVLENAVRQGYPVLLEEINETIDPSLRPILQRETYRFEGRTYLKLGDMVIDY 3096
            .|::||:|||..:|:|||::|.|.||||||:.||:||:|.|||.::.:...||..::|||..|||
Human  3097 GLKIIKLTDSNFLRILENSIRLGLPVLLEELKETLDPALEPILLKQIFISGGRLLIRLGDSDIDY 3161

  Fly  3097 DDNFKLYMTTKLPNPHYLPEVCINVTLVNFLVTESGLEDQLLADIVAIELPAMEIQRNDLVVKIN 3161
            |.||:.|||||:|||||||||||.||::||.||:||||||||:|:|.:|.|.:|.||..|:|:||
Human  3162 DKNFRFYMTTKMPNPHYLPEVCIKVTIINFTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVRIN 3226

  Fly  3162 SDKQQLLALEDKVLKLLFNSEGNILDDEELVETLNDAKETSLIIAARLIDTEETEKVITASRERY 3226
            :||.||..:|:|:|::||.|||||||:|||::||.|:|.||..|..||.:.|.||::|..:||:|
Human  3227 TDKNQLKTIEEKILRMLFTSEGNILDNEELIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKY 3291

  Fly  3227 RILASRGAILYFVVAGLAEIDPMYQYSLKYFTQVFCNVLRLDHPPQSVEVRISTLMTDELRAIFD 3291
            |.:|::|:::|||:|.|:|||||||||||||.|:|...:......::::.|:..|:...|...:.
Human  3292 RPVATQGSVMYFVIASLSEIDPMYQYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTLLTAYV 3356

  Fly  3292 NISRGLFENHKIIFSFLLALSVERQEGRVTEEEFLFLSRGPVGNIRTKIQPAKIK---MSQIEWD 3353
            |:||||||.||:|:||:|.:.:.||:|.:::.|:.|..||..|  ..|.:|.|.:   :....|.
Human  3357 NVSRGLFEQHKLIYSFMLCVEMMRQQGTLSDAEWNFFLRGSAG--LEKERPPKPEAPWLPTATWF 3419

  Fly  3354 SCIFLEDNFSSFFSGLTDE-LDKPFFIQ-------------------------MQENKEVFDFAQ 3392
            :|..||::| ..|.|||.. |..|..|:                         |::.||.
Human  3420 ACCDLEESF-PVFHGLTQNILSHPISIRLGSFETYINPQKWEGYSKMKHEDKHMRQEKEA----- 3478

  Fly  3393 TNQPPTDKWNKRLRVFHKLMFISAFRKPRFLLNVVCYLQSTVGKYFTEASGGTQLSSVYLDTSAV 3457
            .:|.|   |:..|..||||:.|...::.:.:..:..::...:||.|.| :....|.::|.|.|..
Human  3479 AHQDP---WSAGLSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIE-TPPVDLPTLYQDMSCN 3539

  Fly  3458 TPLIFVLSTGSDPMSGFLKFTTQMQFTDKYYSISLGQGQGPLAENLIEKSLRLGHWVFLQNCHLA 3522
            |||:|:||||||||..|.:|..:..::::..||||||||||:||.:::.:::.|:||||||||||
Human  3540 TPLVFILSTGSDPMGAFQRFARESGYSERVQSISLGQGQGPIAEKMVKDAMKSGNWVFLQNCHLA 3604

  Fly  3523 TSFMQTLETIVRNLTLGITKAHVDFRLYLSSMPIQTFPISVLQNSVKITNEPPKGIKANVFGALT 3587
            .|:|..:|.:::..|...:.....|||:|||||..|||::|||||||:|||||||::||:..|.|
Human  3605 VSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMPSNTFPVTVLQNSVKVTNEPPKGLRANIRRAFT 3669

  Fly  3588 DLKQDFFEQHIQNGNWRAIVFGLCMFHAVLLERRKFGPLGWNITYEFSESDRECGLKTLDFFIDR 3652
            ::...|||::|....||.|:||:|.|||::.||:|||||||||.|||::|||||.|..|..:...
Human  3670 EMTPSFFEENILGKKWRQIIFGICFFHAIIQERKKFGPLGWNICYEFNDSDRECALLNLKLYCKE 3734

  Fly  3653 EVLDEIPWEAILYINGDITWGGRVTDYWDLRCLRTILTIFSSKRIIQPDYKYCRGDSYYRDPRKK 3717
               .:|||:|::||.|:||:||||||.||.|||||||..|.|...::.||||.....|:. |...
Human  3735 ---GKIPWDALIYITGEITYGGRVTDSWDQRCLRTILKRFFSPETLEEDYKYSESGIYFA-PMAD 3795

  Fly  3718 TLTEYSAYVQGFPVLEDPEIFGMNQNANIVFQTKETAFFINTLLLGQPRSA-ADEGQAMENEIAQ 3781
            :|.|:..|::..|:::|||||||::|||:|||.|||:..|||:|..||||: ..||:: .:||.|
Human  3796 SLQEFKDYIENLPLIDDPEIFGMHENANLVFQYKETSTLINTILEVQPRSSTGGEGKS-NDEIVQ 3859

  Fly  3782 QTIARIQKALATKIKREPIHDTLSVLDAKGQVPSLTIVLVQEIDRFNIALGIIHDSLVNLSKAIK 3846
            :.:|.:|..:..|::.|...::|.|.|.:|::.|||.||.||:||||..|.:||.||..|:|||.
Human  3860 ELVASVQTRVPEKLEMEGASESLFVKDLQGRLNSLTTVLGQEVDRFNNLLKLIHTSLETLNKAIA 3924

  Fly  3847 GLVVMSEELENVFKALLSNQVPASWAKRSFLSIKPLPSYISDFQRRIDFIQQWAENGAPRSYWIS 3911
            |.||||||:|.|:.:.|:|||||.|:..::.|:|||.|::.|...|..|:..|.:.|.|:|||||
Human  3925 GFVVMSEEMEKVYNSFLNNQVPALWSNTAYPSLKPLGSWVKDLILRTSFVDLWLKRGQPKSYWIS 3989

  Fly  3912 GFFFPQSFLTGVLQTYARRRVLPIDSLKIDFDVFERELVQQDFFEMHTNNMSDQKLYGN--LPEC 3974
            ||||||.||||.||.:||:..||||.|...:.|......|....|........|:|..:  ||..
Human  3990 GFFFPQGFLTGTLQNHARKYNLPIDELSFKYSVIPTYRDQAAVIEAAKTVQFGQELPMDMELPSP 4054

  Fly  3975 TDAIINVHGIFIEAARWDLSKGGLCDANFGELFSRMPVVRFKP--CLEISPTVRYEAPLYKTQQR 4037
            .|.:: |||:|::|:|||..:..:.||..|::...:|||.|:|  ..:.|||: |..|||||..|
Human  4055 EDGVL-VHGMFMDASRWDDKEMVIEDALPGQMNPVLPVVHFEPQQNYKPSPTL-YHCPLYKTGAR 4117

  Fly  4038 SGVLSTTGHSTNFILAVLLRSHNDPEFWIMRGTALVSAVLE 4078
            :|.||||||||||::.|||.|....::||.:|:||:..:.|
Human  4118 AGTLSTTGHSTNFVVTVLLPSKRSKDYWIAKGSALLCQLSE 4158

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhc16F	NP_523394.1	DHC_N2	829..1234	CDD:285579	212/417 (51%)
		P-loop_NTPase	1373..1603	CDD:304359	196/229 (86%)
		P-loop_NTPase	1687..1832	CDD:304359	90/144 (63%)
		P-loop_NTPase	1994..2264	CDD:304359	144/270 (53%)
		P-loop_NTPase	2343..2613	CDD:304359	145/275 (53%)
		MT	2625..2957	CDD:289543	159/331 (48%)
		AAA_9	2985..3201	CDD:289547	133/215 (62%)
		Dynein_heavy	3342..4066	CDD:281078	331/757 (44%)
DNAH6	NP_001361.1	Stem. /evidence=ECO:0000250	1..1433		473/1444 (33%)
		DHC_N2	882..1300	CDD:285579	212/423 (50%)
		P-loop_NTPase	1434..1664	CDD:304359	196/229 (86%)
		AAA 1. /evidence=ECO:0000250	1434..1655		189/220 (86%)
		AAA 2. /evidence=ECO:0000250	1715..1948		124/233 (53%)
		P-loop_NTPase	1748..1893	CDD:304359	90/144 (63%)
		P-loop_NTPase	2057..2328	CDD:304359	144/270 (53%)
		AAA 3. /evidence=ECO:0000250	2058..2306		132/247 (53%)
		AAA 4. /evidence=ECO:0000250	2408..2659		133/257 (52%)
		P-loop_NTPase	2409..2678	CDD:304359	145/275 (53%)
		Stalk. /evidence=ECO:0000250	2676..2961		135/284 (48%)
		MT	2690..3022	CDD:289543	159/331 (48%)
		AAA 5. /evidence=ECO:0000250	3042..3272		143/229 (62%)
		AAA_9	3050..3266	CDD:289547	133/215 (62%)
		Dynein_heavy	3407..4146	CDD:281078	330/755 (44%)
		AAA 6. /evidence=ECO:0000250	3509..3730		112/221 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152608
Domainoid	1	1.000	509	1.000	Domainoid score	I324
eggNOG	1	0.900	-	-		E1_COG5245
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H15221
Inparanoid	1	1.050	3388	1.000	Inparanoid score	I13
Isobase	1	0.950	-	0	Normalized mean entropy	S5775
OMA	1	1.010	-	-		QHG56321
OrthoDB	1	1.010	-	-		D1492at2759
OrthoFinder	1	1.000	-	-		FOG0000321
OrthoInspector	1	1.000	-	-		oto90539
orthoMCL	1	0.900	-	-		OOG6_100025
Panther	1	1.100	-	-	LDO	PTHR10676
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5707
SonicParanoid	1	1.000	-	-		X4342
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	15	14.790