Protein Alignment CG15373 and dnai7

DIOPT Version :9

• Sequence 1: NP_001097013.2
• Gene: CG15373 / 32784
• FlyBaseID: FBgn0030889
• Length: 1162
• Species: Drosophila melanogaster
• Sequence 2: XP_005164821.1
• Gene: dnai7 / 566485
• ZFINID: ZDB-GENE-041210-153
• Length: 731
• Species: Danio rerio
• Alignment Length: 1185
• Identity: 204/1185 - (17%)
• Similarity: 362/1185 - (30%)
• Gaps: 484/1185 - (40%)

  Fly     4 LPP------KKK--LSKKEKARLEAEQAELMRIEMEKEKLKKLEEARQRKKLEMEQAKHRQQQ-- 58
            :||      |||  :||.||.||:.|:.|..:.|.|:.:|  :.|..:.::||.|:.:..:|.
Zfish     1 MPPKDGKSAKKKGGISKAEKERLQREEEEKRQREAEEARL--IAEREENERLERERIEQEKQHIL 63

  Fly    59 EVAENRQRRSQLKDSMLFFDAVRTAIEAIKDGERHERDWEKFMRCNGLPNAASPSDLRKYIHQWH 123
            |:.:..:|..:|.:.....|....|:...:...|.:..||::|.|:|.|:.:...::..||..|.
Zfish    64 ELKDRERREDELNELRHILDENHFAVTVWEAECREKSKWERYMLCDGSPDPSVQPEINTYISLWR 128

  Fly   124 TDIAKRHLESRNWLLRTDERTLLTQDAQVPDLTRISLRQQQGRLGD----VYAHRIKEVLGILNE 184
            .|       |.|.:.:..|...||.:.:         ::....|||    ..|.:.:|.   |..
Zfish   129 DD-------SENQIQKVLEECALTLELE---------KELDFLLGDGPEPSIAEQYQET---LLS 174

  Fly   185 LDEMLPFKQKSALIAADLVKLKTEMRVFLKQHLDEFTYKTMSHIERDMEIDRPGVSKHIYSSDVF 249
            |..::.:|...|  ..:|:|...                                    |:||:.
Zfish   175 LQNLIHYKLNQA--TEELLKFAN------------------------------------YNSDID 201

  Fly   250 QSFVWTFSKDAQISLNPKARIGEQSSHNEIDFPTIEMQISLPPTVHLQSSALRGLWLNYDHFSDY 314
            ...:.|..||..|:|...|.:.:........|..:.:...||..:.:...|:|.|...|||.|.:
Zfish   202 TGNMQTVVKDNNITLCLWANLNKNPRFKGYKFEEVGLGFELPKPLAVIEVAVRILHTRYDHLSHH 266

  Fly   315 CSSYCLKHARSANANILRQTKREWRKRKEILQAMLDDCGREIPLSELEQLTQDQHSASSQPPRER 379
                              ..:.:.:||:.:::|:               |||:..|:::....:.
Zfish   267 ------------------SEREQLQKRRSMMEAI---------------LTQNTESSAAVHNGKM 298

  Fly   380 TYDVDKLYAEYEDELSKAHRRAIGPEAYGMLETDVNLRKYRIIGGVYCIDFLETPQQDKQLNARS 444
            ..:.|      |.|.||                                      |.::..:.||
Zfish   299 EGERD------ESESSK--------------------------------------QVEECHSVRS 319

  Fly   445 FIRTITSANSLVHKEYYQTYKPPPPVLPGVRRLPEEIEAEMRMIEAALDKLALVTLQLPDSVIWF 509
            ..|..::.:.:..||..::...         :|.||.|::|..|
Zfish   320 ESRKRSAVSVISAKEGRKSSSV---------KLLEEGESQMEEI--------------------- 354

  Fly   510 EPPVACRWETNVETLEMELADGMKPEVQKPHGEGDGEADGTGAVSGTAAATTATPTEATPLSTHA 574
                       ..|||.:..|        |:                       |:.|.|:
Zfish   355 -----------TTTLESDQHD--------PY-----------------------PSPAEPV---- 373

  Fly   575 QPSPLKSSPRCPARMRSQKSDIGGESRQQVLREINDFDLRAIPSDVDLYGLVKDFVVPRLPQGFC 639
                                                       :|.|::               .
Zfish   374 -------------------------------------------TDTDVH---------------I 380

  Fly   640 VRLEQSTPVMSTGLRQRKVMFLARQAHIRLGQGKDMADDQLEIPKELQRLQLNSKPGLGAEFLDT 704
            |.|:|.||                                                 ||..|.
Zfish   381 VDLQQFTP-------------------------------------------------LGGVFY-- 394

  Fly   705 EEPAEMFPPLCFDKLLKFRQMAPRSRGPAHLQGYLFSQLIDDMDRLWRLQLPRDQQEEIIQQISE 769
                       ||..    .|.|:||   .::|:...:|:|
Zfish   395 -----------FDLF----HMPPQSR---TVKGWEMRELLD------------------------ 417

  Fly   770 QLSPTGSRTSEPGEKEPRETENDGDLAENMQPLSQELVDVLQPATAAAAFAYYTGISFVRDSQLP 834
                                                        |....|.|
Zfish   418 --------------------------------------------TGLQVFPY------------- 425

  Fly   835 AEPEPESSAKRSNSMDSSEDDDDDVDSL-----------VELLEGASTAANTLHDLLGPATNSDN 888
              |..:|..:.|.|:...|..:..|.||           |..||....|.   .|.:|.
Zfish   426 --PTEQSRIQSSTSVKLDEHSNTTVASLPVGVTVALPHSVLFLEDPQVAR---WDPIGQ------ 479

  Fly   889 SDSESKQKMSNVAAITQGKWSTRDVHDTKFNEDKLSIQFRTGRLGIFGFALNKYSNMPYQTWDLR 953
                              .|.|..:.:|.::.:..:|.|:......|......|:|||:|:|:||
Zfish   480 ------------------HWRTDCISETSYDAESRTISFQMTAFYAFTLLQETYANMPFQSWELR 526

  Fly   954 PDMKNPGTIIFSFTASLISLDMTITKSGYTVNNFQGGSTQGITDMIGKTLSLSELKATLILSAVD 1018
            |  ....:.:|:.|.:||.:.:|:......::..:   |:.:..::||.:|.|||:..:..:.::
Zfish   527 P--LGQDSALFTITGALIEVSITVKGKQCMLHTEE---TKDLDHLLGKWMSPSELQKAMRKAGIN 586

  Fly  1019 IFPDEDAFCYTEGSCEKNYVMEMHCYACLSTLAQSHNFSWSRWNLLAGSRTAVLLVRELIEGKKV 1083
            ||.:|.:..|...:. |:.::|...|..::.::.:..|||||||........||...|.:|...|
Zfish   587 IFVNEYSDKYVSINL-KDPLIEHAVYEQMALMSSAVAFSWSRWNAQCRQEHLVLQACEQMEVGPV 650

  Fly  1084 --PYYSTLLVTPLKTSIIDCTEVSASFNAVGIPGMEYYAD-LYQLSQAHAQPGSLEKQRTMNPVL 1145
              ..:|..|:...:...:...|...||:.....|.|:::. |:.|.|..:..|. .:.|..:.:.
Zfish   651 AEEAWSLYLLGAQRNQHLKMKEQEDSFSPELAEGSEFHSTFLHMLRQDMSTEGQ-ARVRQSHHLY 714

  Fly  1146 RDNVAKILMAIRPLS 1160
            .|.|.::|.|.|.|:
Zfish   715 IDTVQRLLCATRVLT 729

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15373	NP_001097013.2	Casc1_N	14..267	CDD:406371	54/258 (21%)
		Casc1	287..515	CDD:372076	33/227 (15%)
		Casc1	908..1118	CDD:372076	52/211 (25%)
dnai7	XP_005164821.1	Casc1_N	64..227	CDD:292549	41/219 (19%)
		Casc1	244..471	CDD:289161	72/589 (12%)
		Casc1	481..>635	CDD:289161	41/159 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576059
Domainoid	1	1.000	71	1.000	Domainoid score	I9431
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	160	1.000	Inparanoid score	I4216
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D526857at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto41488
orthoMCL	1	0.900	-	-		OOG6_104946
Panther	1	1.100	-	-	LDO	PTHR20929
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5140
SonicParanoid	1	1.000	-	-		X3892
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.930