Protein Alignment CG15373 and Dnai7

DIOPT Version :9

• Sequence 1: NP_001097013.2
• Gene: CG15373 / 32784
• FlyBaseID: FBgn0030889
• Length: 1162
• Species: Drosophila melanogaster
• Sequence 2: XP_038963394.1
• Gene: Dnai7 / 297720
• RGDID: 1311213
• Length: 767
• Species: Rattus norvegicus
• Alignment Length: 1232
• Identity: 210/1232 - (17%)
• Similarity: 355/1232 - (28%)
• Gaps: 551/1232 - (44%)

  Fly     5 PPKKKLSKKEKARLEAEQAEL-------MRIEMEKEKLKKLEEAR-QRKK---LEMEQAKHRQQ- 57
            |.|||::|.|:.||..|:.|.       .|::.|||:.::||:.| :|:|   ||.:..|:..|
  Rat     9 PTKKKITKAERLRLLQEEEEKRLKEEEEARLKYEKEEQERLEKQRIEREKWNLLEKKVNKYECQL 73

  Fly    58 ------------------------QEVAENRQRRSQLKDSMLFFDAVRTAIEAIKDGERHERDWE 98
                                    ....::.:|||:..:.:...:......|..|...|....|:
  Rat    74 GCYPLLHWGCSVPSPAFTACGASPHMCFQDLERRSEELEELALLECCFPEAEKQKREMRVLAQWK 138

  Fly    99 KFMRCNGLPNAASPSDLRKYIHQWH---TDIAKRHLESRNWLLRTDER-TLLTQDAQVPDLTRIS 159
            .:..|:|.|:.....::..:|..|.   .:..::.:|....:|...|: .|:..:....||.:.:
  Rat   139 HYTECDGSPDPRIAQEMNTFISLWEEEKNETFEQVMEKSKLVLSLIEKLKLILLETPSCDLDKST 203

  Fly   160 LRQQQGRLGDVYAHRIKEVLGI-LNELDEMLPFKQKSALIAADLVKLKTEMRVFLKQHLDEFTYK 223
            :.|.||.:     .|::|:|.: :|...|:| .:|.|.|  |||
  Rat   204 VLQYQGSI-----LRLQELLSLKVNVATELL-LRQASNL--ADL--------------------- 239

  Fly   224 TMSHIERDMEIDRPGVSKHIYSSDVFQSFVWTFSKDAQISLNPKARIGEQSSHNEIDFPTIEMQI 288
                       |...:.|.|...:| ..:||     |.:..||:.|        .:.|...::..
  Rat   240 -----------DTGNMEKIIKDENV-TLYVW-----ANLKKNPRYR--------TVKFSQTQVGF 279

  Fly   289 SLPPTVHLQSSALRGLWLNYDHFSDYCSSYCL--KHARSANANILRQTKREWRKRKEILQAMLDD 351
            .:|..:...:.|||.|..:|||.:...|:...  ||......|.    |.|.|..|.:.:   ::
  Rat   280 EIPRILATSNVALRLLHTHYDHITPLFSTVVTEEKHGSIVAENF----KEEERTEKAVPE---EN 337

  Fly   352 CGREIPLSELEQL-TQDQHSASSQPPRERTYD--VDKLYAEYED-------------------EL 394
            ...|....|.||| .:::...||.|..|..:|  ||.:..:..|                   |.
  Rat   338 VFTEEAADEAEQLKAEEERELSSIPEEEVKFDPTVDTVTQKISDPEEEESQTTQFELERKLLSET 402

  Fly   395 SKAHRRAIGPEAYGMLET----DVNLRKYRIIGGVYCIDFLETPQQDKQLNARSFIRTITSANSL 455
            ..|.:.::......|.||    :||:..:..:||||.::.||.|.|.|.:.......
  Rat   403 VSAAQLSLIENVLEMPETLEPYEVNMCHFAPLGGVYHLEILELPPQSKPVKGWVLAE-------- 459

  Fly   456 VHKEYYQTYKPPPPVLPGVRRLPEEIEAEMRM--IEAALDKLALVTLQLPDSVIWFEPPVACRWE 518
            :.:|..|.:..||       ...||.:.|...  ||        |||::.:|.|:||.|...||
  Rat   460 IRQEGLQKFTYPP-------ENTEEPDPESAFPPIE--------VTLEIHESAIFFEDPQVVRW- 508

  Fly   519 TNVETLEMELADGMKPEVQKPHGEGDGEADGTGAVSGTAAATTATPTEATPLSTHAQPSPLKSSP 583
                                       :|:|
  Rat   509 ---------------------------DAEG---------------------------------- 512

  Fly   584 RCPARMRSQKSDIGGESRQQVLREINDFDLRAIPSDVDLYGLVKDFVVPRLPQGFCVRLEQSTPV 648
                                                                             
  Rat   513 ----------------------------------------------------------------- 512

  Fly   649 MSTGLRQRKVMFLARQAHIRLGQGKDMADDQLEIPKELQRLQLNSKPGLGAEFLDTEEPAEMFPP 713
                                                                             
  Rat   513 ----------------------------------------------------------------- 512

  Fly   714 LCFDKLLKFRQMAPRSRGPAHLQGYLFSQLIDDMDRLWRLQLPRDQQEEIIQQISEQLSPTGSRT 778
                                               :.||
  Rat   513 -----------------------------------KFWR-------------------------- 516

  Fly   779 SEPGEKEPRETENDGDLAENMQPLSQELVDVLQPATAAAAFAYYTGISFVRDSQLPAEPEPESSA 843
                        :||                       ....||.     |:::|
  Rat   517 ------------SDG-----------------------VTCVYYN-----RENRL---------- 531

  Fly   844 KRSNSMDSSEDDDDDVDSLVELLEGASTAANTLHDLLGPATNSDNSDSESKQKMSNVAAITQGKW 908
             .:.|:|:                            :||.|
  Rat   532 -LTFSIDT----------------------------MGPVT------------------------ 543

  Fly   909 STRDVHDTKFNEDKLSIQFRTGRLGIFGFALNKYSNMPYQTWDLRPDMKNPGTIIFSFTASLISL 973
            ..:|.|                            .|||||:|:|.|...|...::  .|...|.|
  Rat   544 LIQDAH----------------------------VNMPYQSWELSPLGMNKALLM--VTTVFIEL 578

  Fly   974 DMTI--TKSGYTVNNFQGGSTQGITDMIGKTLSLSELKATLILSAVDIFPDEDAFCYTEGSCEKN 1036
            .:.|  |.........:|.|.:  ..:|||.::.......|..:.::|||...:..|.   ...|
  Rat   579 QIHIKETHCMLAAVKLKGKSRE--LRVIGKWMTPIPFILALKEAGLNIFPAVYSHFYV---VVNN 638

  Fly  1037 YV--MEMHCYACLSTLAQSHNFSWSRWNLLAGSRTAVLLVRELI-EGKKVPYYSTLLVTPLKTSI 1098
            .|  ||:..|..::.|:.:.:|.||:||::..|...|..|||.| |.::...::.|:.:..:..:
  Rat   639 KVPQMELKAYRQMALLSSAFSFGWSKWNMVCNSTRVVFRVREHISEEEEQNTWALLMFSGDRAQM 703

  Fly  1099 IDCTEVSASFNAVGIPGMEYYADLYQLSQAHAQPGSLEKQRTMNPVLRDNVAKILMAIRPLS 1160
            :...|.|..|:.....|.|:::.||.:.:..|.|.:.||.|..|....|:|..:|:::|.||
  Rat   704 LKMQEESDQFSETLREGSEFHSTLYHMMKDFASPEATEKVRHSNCQFIDSVCYMLLSVRVLS 765

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15373	NP_001097013.2	Casc1_N	14..267	CDD:406371	59/293 (20%)
		Casc1	287..515	CDD:372076	62/257 (24%)
		Casc1	908..1118	CDD:372076	49/214 (23%)
Dnai7	XP_038963394.1	Casc1_N	37..266	CDD:406371	54/274 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336922
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I4141
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D526857at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto97493
orthoMCL	1	0.900	-	-		OOG6_104946
Panther	1	1.100	-	-	LDO	PTHR20929
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3892
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.900