DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6867 and DIP-epsilon

DIOPT Version :9

Sequence 1:	NP_573262.2	Gene:	CG6867 / 32782	FlyBaseID:	FBgn0030887	Length:	949	Species:	Drosophila melanogaster
Sequence 2:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster

Alignment Length:	282	Identity:	86/282 - (30%)
Similarity:	138/282 - (48%)	Gaps:	38/282 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   427 LLIPPSITDIQVPDFQRTVIVEEGRSLNLSCTATGTPTPQVEWRREDGRTINVN-GVEMASISGQ 490
            :::||:|.|...   ...:||.||.::.|.|.|.|:|.|.::|:|:||..|.:| .:|:..:...
  Fly   153 VVVPPNIDDALT---SSDIIVREGDNVTLRCKAKGSPEPTIKWKRDDGNKIVINKTLEVHDLETD 214

  Fly   491 FLRFTNITRHQMAAYTCFANNGIAPVANATYLVEVQFAPMISVYRQMIYAEYQSSATLECLVEAF 555
            .|....|:|..|.||.|.|:||:.|..:....|.|.|:||:.:..|::......:.||||.:||.
  Fly   215 SLELERISRLHMGAYLCIASNGVPPSVSKRIKVSVDFSPMVWIPHQLVGIPIGFNITLECFIEAN 279

  Fly   556 PEAIRYWERAYDGKILDPSDKYGIESYP--EGFKTTMRLTISNLRKDDFGYYHCVARNELNATMV 618
            |.::.||.|..| :::..|.||..|:.|  ..:|.||||||:|::..|:|.|.|||:|
  Fly   280 PTSLNYWTREND-QMITESSKYKTETIPGHPSYKATMRLTITNVQSSDYGNYKCVAKN------- 336

  Fly   619 NFEIAPQDPNSETPYVGNNMKVYGQRPPESECPVCDQCPDPSLYQCKDSILNNFEIQATGNLSYP 683
                    |..:   :..|:|:|...||.::       |.|:....:.:.....||...|.::.|
  Fly   337 --------PRGD---MDGNIKLYMSSPPTTQ-------PPPTTTTLRRTTTTAAEIALDGYINTP 383

  Fly   684 ------GLPKRPKTCYLYAVGK 699
                  |:.....|..:.|.||
  Fly   384 LNGNGIGIVGEGPTNSVIASGK 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6867	NP_573262.2	Collagen	306..364	CDD:189968
		IG_like	442..525	CDD:214653	29/83 (35%)
		IGc2	449..511	CDD:197706	23/62 (37%)
		IG_like	544..612	CDD:214653	30/69 (43%)
		Ig	546..612	CDD:143165	30/67 (45%)
		OLF	694..937	CDD:280371	3/6 (50%)
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	0/1 (0%)
		Ig	69..139	CDD:143165
		IG_like	165..249	CDD:214653	29/83 (35%)
		IGc2	172..237	CDD:197706	24/64 (38%)
		IG_like	267..348	CDD:214653	34/99 (34%)
		Ig	270..339	CDD:299845	32/84 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	50	1.000	Domainoid score	I11661
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm26286
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920