DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6867 and olfml3a

DIOPT Version :9

Sequence 1:	NP_573262.2	Gene:	CG6867 / 32782	FlyBaseID:	FBgn0030887	Length:	949	Species:	Drosophila melanogaster
Sequence 2:	NP_001039322.1	Gene:	olfml3a / 568106	ZFINID:	ZDB-GENE-060825-31	Length:	394	Species:	Danio rerio

Alignment Length:	409	Identity:	90/409 - (22%)
Similarity:	165/409 - (40%)	Gaps:	67/409 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   548 LECLVEAFPEAIRYWERAYDGKILDPSDKYGIESYPEGFKTTMRLTISNLRKDDFGYYHCVARNE 612
            ||..:.|..|.|..|.        :.:::|  .|..:.|:......:..|.||     |...|::
Zfish    29 LENRMLAMEERIALWH--------EQNNRY--NSDLKEFRQQAADLLEKLSKD-----HSKLRSD 78

  Fly   613 LNATMVNFEIAPQDPNSETPYVGNNMKVYGQRPPESECPVCDQCPDPSLYQCKDSILNN------ 671
            |.......:...:    |..|:..      :.||:.    |.:..|..:.|  |:::..
Zfish    79 LEGAGARVDRVER----EMDYIET------KNPPKP----CVKAADKMVEQ--DAVIKEKKKEEF 127

  Fly   672 FEIQATGNLSYPGLPKRPKTCYLYAVGKPVFHKVVNEKFGSWLRDPSPDSDREKTFVTNENDPYN 736
            ||:....|:    :........|..:|.|.         |.|.:    |:...|.:|.|......
Zfish   128 FELSVCVNI----ISSLKAMKILKRLGSPK---------GLWTK----DARSAKIYVFNGTSDNT 175

  Fly   737 LFEFTTRIQYRMNS--IPRRKYEIQEGFHGNAHVVFNGSFYYQQRNSDL-VVKLDLT-SLKKITT 797
            |:||::..:...:|  ...::..:...::|..|.|::|..||...:|:| |||.||| |....|.
Zfish   176 LYEFSSMRELSSSSGVSKGKQITVPTAWNGTGHAVYDGFLYYISESSELQVVKYDLTNSSVADTA 240

  Fly   798 QLPYAGVAAANRLYTTDYNYMDFNVDEVGLWVIYSTYNSNNTLVAKLDAETLKMQYNFNITLDHH 862
            .||....:...:|  .....:|...||.|||.:|...::.|  :||:|:.:|.::..::......
Zfish   241 VLPMEERSPVYQL--NPETLVDLVADEDGLWALYPAGDTIN--LAKMDSNSLDIEQMWDTACPRS 301

  Fly   863 QFGEMFIVCGNLYAI-DSGTDKNTQIRYVVDLYKGKLLNTNLP---FSNPFSHTTTVGYNPLTVE 923
            .....|||||.:|.: ::.....::::.|.|: ...:.|...|   |...:...:::.|||...:
Zfish   302 NAEAAFIVCGTVYVVYNTKPPSRSRVQCVFDV-NDMVSNGEAPLIYFPRRYGAHSSLKYNPEERQ 365

  Fly   924 LYSWDKGNALTYPIRYNEQ 942
            ||:||.|..:.|.:...::
Zfish   366 LYAWDDGYQILYKLELKKK 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6867	NP_573262.2	Collagen	306..364	CDD:189968
		IG_like	442..525	CDD:214653
		IGc2	449..511	CDD:197706
		IG_like	544..612	CDD:214653	14/63 (22%)
		Ig	546..612	CDD:143165	14/63 (22%)
		OLF	694..937	CDD:280371	64/250 (26%)
olfml3a	NP_001039322.1	OLF	137..375	CDD:280371	63/255 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23192
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910