DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6867 and olfm3b

DIOPT Version :9

Sequence 1:	NP_573262.2	Gene:	CG6867 / 32782	FlyBaseID:	FBgn0030887	Length:	949	Species:	Drosophila melanogaster
Sequence 2:	XP_690154.2	Gene:	olfm3b / 561648	ZFINID:	ZDB-GENE-070912-606	Length:	457	Species:	Danio rerio

Alignment Length:	398	Identity:	91/398 - (22%)
Similarity:	167/398 - (41%)	Gaps:	83/398 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   592 LTISNLR-KDDFGYYHCVARNELNATMVNFEIAPQDPNSETPYVGNNMKVYGQ-RPPESECPVCD 654
            :.:.||| :.||.|   |.:.|.....:..:....:.|..|....|..::.|: ...:...||.:
Zfish    79 IEVLNLRTQRDFQY---VMKMESQMKGLRSKFRQIESNRRTLLTKNFQELKGKMNELQPLIPVLE 140

  Fly   655 QCPDPSLYQCKDSILNNFEIQATGNLSYP---------------------GLPKRPKTCY----- 693
            |      |:...|:::.|: :...|||..                     ||..|.:.|.
Zfish   141 Q------YKTDASLISQFK-EELRNLSVVLMAIQEEIGAYDYEELQQRVLGLEGRLRNCMNKLTC 198

  Fly   694 --LYAVGKPVFHKVVNEKFGSWLRDPSPDSDREK-----TFVTNE--NDPYNLFEFTTRIQYRMN 749
              |..:..|:..|....:||:|:.||.......|     ::..|:  .:..::.:|...::.:..
Zfish   199 GKLMKITGPITVKTSGTRFGAWMTDPQASPKNNKVWYMDSYTNNKIVREYKSVSDFVAGVESKTY 263

  Fly   750 SIPRRKYEIQEGFH--GNAHVVFNGSFYYQQRNSDLVVKLDLTSLKKITTQ--LPYAGVAAANRL 810
            ::|         ||  |..|||:|||.||.:..|:::|:....| .::|||  |..||.......
Zfish   264 NLP---------FHWAGTNHVVYNGSLYYNKYQSNIIVRYSFES-GRVTTQRALESAGFHNVYPY 318

  Fly   811 YTTDYNYMDFNVDEVGLWVIYST-YNSNNTLVAKLDAETLKMQYNFNITLDHHQFGEMFIVCGNL 874
            ....::.:|...||:|||.||:| .|:.|.::::||.:|:::..::|........||.|::||.|
Zfish   319 TWGGFSDIDLMADELGLWAIYATNQNAGNIVISRLDPQTIQVLNSWNTEYSKRNAGESFMICGTL 383

  Fly   875 YAIDSG----------TDKNTQIRYVVDLYKGKLLNTNLPFSNPFSHTTTVGYNPLTVELYSWDK 929
            |..:|.          :.|.:...|:           ::|..|.:.|.:.:.||.....||.|:.
Zfish   384 YITNSHLTGAKVYYSYSTKTSTYEYM-----------DIPIHNQYFHMSMLDYNARDRALYGWNN 437

  Fly   930 GNALTYPI 937
            |:.:.:.:
Zfish   438 GHQVLFNV 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6867	NP_573262.2	Collagen	306..364	CDD:189968
		IG_like	442..525	CDD:214653
		IGc2	449..511	CDD:197706
		IG_like	544..612	CDD:214653	7/20 (35%)
		Ig	546..612	CDD:143165	7/20 (35%)
		OLF	694..937	CDD:280371	66/264 (25%)
olfm3b	XP_690154.2	Noelin-1	27..123	CDD:289107	11/46 (24%)
olfm3b	XP_690154.2	OLF	201..445	CDD:280371	66/264 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	125	1.000	Domainoid score	I5398
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR23192
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X205
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	4.010