DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6867 and myoc

DIOPT Version :9

Sequence 1:	NP_573262.2	Gene:	CG6867 / 32782	FlyBaseID:	FBgn0030887	Length:	949	Species:	Drosophila melanogaster
Sequence 2:	NP_001015062.1	Gene:	myoc / 548602	ZFINID:	ZDB-GENE-050425-2	Length:	474	Species:	Danio rerio

Alignment Length:	358	Identity:	87/358 - (24%)
Similarity:	147/358 - (41%)	Gaps:	70/358 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   624 PQDPNSETP---YVGNNMKVYGQRPPESECPVCD---QCPDPSLYQCKDSILNNF---------E 673
            ||..||..|   :|.:|:......|.|.:..:.|   |..:|. ||...:::...         :
Zfish   147 PQKDNSFRPGSGHVPSNLASRPGNPQEDKSSLRDPAWQYSNPG-YQELTAVVTEVTAPNQDGPAD 210

  Fly   674 IQATGNLSYPGLPKRPKTCYLYAVGKPVFHKVVNE---KFGSWLRDPSPDSDREKTFVTNENDPY 735
            |...|:|.:              |..|..|:..:.   |:|.|::||            ...:||
Zfish   211 ISGCGDLVW--------------VENPEVHRKADSIAGKYGVWMQDP------------EAKEPY 249

  Fly   736 ----------------NLFEFTTRIQYRMNSIPRRKYEIQEGFHGNAHVVFNGSFYYQQRNSDLV 784
                            .||.:....|. ....|.:...:.|........::.||.|||:|.|..:
Zfish   250 GPDMVWRIDSVGSEVRQLFGYENMDQL-TRGFPTKVLLLPESVESTGATMYKGSLYYQRRLSRTL 313

  Fly   785 VKLDLTSLKKITTQ--LPYAGVAAANRLYTTDYNYMDFNVDEVGLWVIYSTYNSNNTLV-AKLDA 846
            ::.||.: :.|..:  ||:||...........|..:|..:||.|||.||||..:...:| ::||.
Zfish   314 IRYDLHA-ESIAARRDLPHAGFHGQFPYSWGGYTDIDLAIDENGLWAIYSTNKAKGAIVISQLDP 377

  Fly   847 ETLKMQYNFNITLDHHQFGEMFIVCGNLYAIDSGTDKNTQIRYVVD--LYKGKLLNTNLPFSNPF 909
            ..|:::..:...:........|::||.||.:.|.|..||.:.|:.|  ..:||.:  ::||.|.:
Zfish   378 HNLEVKGTWETKIRKTSVANAFMICGKLYTVASYTSPNTTVNYMFDTATSQGKAI--SVPFKNRY 440

  Fly   910 SHTTTVGYNPLTVELYSWDKGNALTYPIRYNEQ 942
            .:.:.|.||....:||:||....::|.:|..:|
Zfish   441 RYNSMVDYNSAKRKLYAWDNYYMVSYSVRLGKQ 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6867	NP_573262.2	Collagen	306..364	CDD:189968
		IG_like	442..525	CDD:214653
		IGc2	449..511	CDD:197706
		IG_like	544..612	CDD:214653
		Ig	546..612	CDD:143165
		OLF	694..937	CDD:280371	68/266 (26%)
myoc	NP_001015062.1	DUF4482	104..>188	CDD:291484	11/40 (28%)
myoc	NP_001015062.1	OLF	217..468	CDD:280371	69/280 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	125	1.000	Domainoid score	I5398
eggNOG	1	0.900	-	-		E1_KOG3545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23192
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3311
SonicParanoid	1	1.000	-	-		X205
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.940