DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6867 and IGLON5

DIOPT Version :9

Sequence 1:NP_573262.2 Gene:CG6867 / 32782 FlyBaseID:FBgn0030887 Length:949 Species:Drosophila melanogaster
Sequence 2:NP_001094842.1 Gene:IGLON5 / 402665 HGNCID:34550 Length:336 Species:Homo sapiens


Alignment Length:211 Identity:62/211 - (29%)
Similarity:89/211 - (42%) Gaps:33/211 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly   429 IPPSITDIQVPDFQRTVIVEEGRSLNLSCTATGTPTPQVEWRR-EDGRTINVNGVEMASISGQFL 492
            :|..|.:|..|     |.|.||.::||.|.|.|.|.|.|.||: .||.|          ..|:.|
Human   131 VPARIVNISSP-----VTVNEGGNVNLLCLAVGRPEPTVTWRQLRDGFT----------SEGEIL 180

  Fly   493 RFTNITRHQMAAYTCFANNGI--APVANATYLVEVQFAPMISVYRQMIYAEYQSSATLECLVEAF 555
            ..::|.|.|...|.|..:||:  ||.:... ||.|.:.|.|:.......| ...:|.|.|...|.
Human   181 EISDIQRGQAGEYECVTHNGVNSAPDSRRV-LVTVNYPPTITDVTSARTA-LGRAALLRCEAMAV 243

  Fly   556 PEAIRYWERAYDGKILDPSDKYGIESYPEGFKTTMRLTISNLRKDDFGYYHCVARNELNATMVNF 620
            |.|...|.:  |.::|......|::...|  :|...|..:|:....:|.|.|.|.|.|.|:..:.
Human   244 PPADFQWYK--DDRLLSSGTAEGLKVQTE--RTRSMLLFANVSARHYGNYTCRAANRLGASSASM 304

  Fly   621 EI---------APQDP 627
            .:         ||:.|
Human   305 RLLRPGSLENSAPRPP 320

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6867NP_573262.2 Collagen 306..364 CDD:189968
IG_like 442..525 CDD:214653 30/85 (35%)
IGc2 449..511 CDD:197706 22/62 (35%)
IG_like 544..612 CDD:214653 18/67 (27%)
Ig 546..612 CDD:143165 18/65 (28%)
OLF 694..937 CDD:280371
IGLON5NP_001094842.1 Ig 41..129 CDD:416386
Ig strand A' 41..46 CDD:409353
Ig strand B 48..56 CDD:409353
CDR1 56..60 CDD:409353
FR2 61..68 CDD:409353
Ig strand C 61..67 CDD:409353
CDR2 69..79 CDD:409353
Ig strand C' 71..74 CDD:409353
Ig strand C' 76..79 CDD:409353
FR3 80..115 CDD:409353
Ig strand D 84..91 CDD:409353
Ig strand E 94..100 CDD:409353
Ig strand F 107..115 CDD:409353
CDR3 116..120 CDD:409353
Ig strand G 120..129 CDD:409353
FR4 122..129 CDD:409353
Ig_3 134..199 CDD:404760 27/79 (34%)
Ig strand B 148..157 CDD:409353 3/8 (38%)
Ig strand C 162..170 CDD:409353 4/7 (57%)
Ig strand F 191..199 CDD:409353 2/7 (29%)
Ig strand G 202..212 CDD:409353 2/10 (20%)
Ig_3 217..295 CDD:404760 21/82 (26%)
putative Ig strand A 218..224 CDD:409353 2/5 (40%)
Ig strand B 234..238 CDD:409353 2/3 (67%)
Ig strand C 247..251 CDD:409353 0/3 (0%)
Ig strand E 274..278 CDD:409353 1/3 (33%)
Ig strand F 288..293 CDD:409353 2/4 (50%)
Ig strand G 301..304 CDD:409353 0/2 (0%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 57 1.000 Domainoid score I10858
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D265311at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.920

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