DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6867 and Olfm2

DIOPT Version :9

Sequence 1:	NP_573262.2	Gene:	CG6867 / 32782	FlyBaseID:	FBgn0030887	Length:	949	Species:	Drosophila melanogaster
Sequence 2:	NP_001015017.1	Gene:	Olfm2 / 313783	RGDID:	1309741	Length:	478	Species:	Rattus norvegicus

Alignment Length:	563	Identity:	131/563 - (23%)
Similarity:	212/563 - (37%)	Gaps:	152/563 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   405 IPGVPGINAWKLQYPNGSSSNDLLIPPSITDIQVPDFQRTVIVEEGRSLNLSCTATGTPTPQVEW 469
            :|.:.|:|:...:  .|||.       .||..|.|        |||..|..|..|
  Rat    26 LPSLVGLNSTVSR--AGSSE-------KITLFQSP--------EEGWQLYTSAQA---------- 63

  Fly   470 RREDGRTINVNGVEMASISGQFLRFTNITRHQMAAYTCFANNG--------IAPVANATYLVEVQ 526
              .||:.|                   .|....|..|| |.:|        :..|.|.:..:||.
  Rat    64 --PDGKCI-------------------CTAVIPAQSTC-ARDGRSRELRQLMEKVQNVSQSMEVL 106

  Fly   527 FAPMISVYRQMIYAEYQSSATLECLVEAFPEAIRYWERAYDGKILDPS---------DKYGIESY 582
               .:..||.:.|..     ::|.|:.:....:    |..||.:...|         :...:.|.
  Rat   107 ---ELRTYRDLQYVR-----SMETLMRSLDARL----RTADGSVSAKSFQELKDRMTELLPLSSV 159

  Fly   583 PEGFKTTMRLTISNLRKDDFGYYHCVARNELNATMVNFEIAPQDPNSETPYVGNNMKVYGQRPPE 647
            .|.:|...| ||..||::        .|| |:..:...:              ..|..||....:
  Rat   160 LEQYKADTR-TIVRLREE--------VRN-LSGNLAAIQ--------------EEMGAYGYEDLQ 200

  Fly   648 SECPVCDQCPDPSLYQCKDSILNNFEIQATGNLSYPGLPKRPKTCYLYAVGKPVFHKVVNEKFGS 712
            ...    ...:..|:.|...:               |..|      |..|..|:..:.:..:|||
  Rat   201 QRV----MALEARLHACAQKL---------------GCGK------LTGVSNPITIRAMGSRFGS 240

  Fly   713 WLRDP-SPDSDREKTFVTNENDPYNLFEFTTRIQY--RMNSIPRRKYEIQEGFHGNAHVVFNGSF 774
            |:.|. :|.:|....::........:.||.|...:  ..|.|   ::.:.:.:.|..|||:|||.
  Rat   241 WMTDTMAPSADSRVWYMDGYYKGRRVLEFRTLGDFIKGQNFI---QHLLPQPWAGTGHVVYNGSL 302

  Fly   775 YYQQRNSDLVVKLDLTSLKKITTQ--LPYAGVAAANRLYTTDYNY-------MDFNVDEVGLWVI 830
            :|.:..|::|||....| :.:..|  ||.||       |...:.|       |||.|||.|||.:
  Rat   303 FYNKYQSNVVVKYHFRS-RSVLVQRSLPGAG-------YNNTFPYSWGGFSDMDFMVDESGLWAV 359

  Fly   831 YST-YNSNNTLVAKLDAETLKMQYNFNITLDHHQFGEMFIVCGNLYAIDSGTDKNTQIRYVVDLY 894
            |:| .|:.|.:|::||..||::..:::........||.|::||.||..:|.. ...::.:.....
  Rat   360 YTTNQNAGNIVVSRLDPHTLEVVRSWDTGYPKRSAGEAFMICGVLYVTNSHL-AGAKVYFAYFTN 423

  Fly   895 KGKLLNTNLPFSNPFSHTTTVGYNPLTVELYSWDKGNALTYPI 937
            ......|::||.|.:||.:.:.|||....||:|:.|:.:.|.:
  Rat   424 TSSYEYTDVPFHNQYSHISMLDYNPRERALYTWNNGHQVLYNV 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6867	NP_573262.2	Collagen	306..364	CDD:189968
		IG_like	442..525	CDD:214653	17/90 (19%)
		IGc2	449..511	CDD:197706	13/61 (21%)
		IG_like	544..612	CDD:214653	15/76 (20%)
		Ig	546..612	CDD:143165	15/74 (20%)
		OLF	694..937	CDD:280371	75/255 (29%)
Olfm2	NP_001015017.1	Noelin-1	49..144	CDD:289107	30/146 (21%)
Olfm2	NP_001015017.1	OLF	222..466	CDD:280371	75/255 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	127	1.000	Domainoid score	I5230
eggNOG	1	0.900	-	-		E1_KOG3545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23192
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X205
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.910