DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6867 and DIP-alpha

DIOPT Version :9

Sequence 1:	NP_573262.2	Gene:	CG6867 / 32782	FlyBaseID:	FBgn0030887	Length:	949	Species:	Drosophila melanogaster
Sequence 2:	NP_001259218.1	Gene:	DIP-alpha / 31322	FlyBaseID:	FBgn0052791	Length:	554	Species:	Drosophila melanogaster

Alignment Length:	315	Identity:	96/315 - (30%)
Similarity:	148/315 - (46%)	Gaps:	58/315 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   426 DLLIPPSITDIQVPDFQRTVIVEEGRSLNLSCTATGTPTPQVEWRREDGRTI----NVNGVEMA- 485
            |::|||   |....|....|||.||.|:.|:|.|.|.|.|.|.||||||..|    ||....:|
  Fly   139 DVVIPP---DFISEDTSSDVIVPEGSSVRLTCRARGYPEPIVTWRREDGNEIVLKDNVGTKTLAP 200

  Fly   486 SISGQFLRFTNITRHQMAAYTCFANNGIAPVANATYLVEVQFAPMISVYRQMIYAEYQSSATLEC 550
            |..|:.|:.:.|:|::|.:|.|.|:||:.|..:....:.:.|.|:|.|..|::.|...:...:||
  Fly   201 SFRGEVLKLSKISRNEMGSYLCIASNGVPPSVSKRISLSIHFHPVIQVPNQLVGAPLGTDVQIEC 265

  Fly   551 LVEAFPEAIRYWERAYDGKILDPSDKYGI-ESYPEGFKTTMRLTISNLRKDDFGYYHCVARN--- 611
            .|||.|::|.||.:. .|:::..|.||.: ||....::|.|.:.:...:|||.|.|.|:|:|
  Fly   266 HVEASPKSINYWIKD-TGEMIVTSGKYHVQESSQSMYETKMSMIVRKFQKDDVGSYRCIAKNSLG 329

  Fly   612 ELNATMVNFEIAPQDPNSETPYVG----------------------NNMKVYGQRPPESECPVCD 654
            |:::::..:|| |....::.|..|                      ..:||..|  ||.|
  Fly   330 EVDSSIRLYEI-PGPNRNKNPLNGGGKGGGAGGSLDADANDILKQKQQVKVTYQ--PEDE----- 386

  Fly   655 QCPDPSLYQCKDSILNNFEIQA--TGNLSYPGLPKRPKTCYLYAVGKPVFHKVVN 707
                    :.:...:.:||.:.  .|.|:    |..|.. |..:..||..||..|
  Fly   387 --------ELQYGSVEDFEAEGGEGGGLT----PLSPHV-YYTSGNKPATHKPGN 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6867	NP_573262.2	Collagen	306..364	CDD:189968
		IG_like	442..525	CDD:214653	35/87 (40%)
		IGc2	449..511	CDD:197706	29/66 (44%)
		IG_like	544..612	CDD:214653	25/71 (35%)
		Ig	546..612	CDD:143165	25/69 (36%)
		OLF	694..937	CDD:280371	5/14 (36%)
DIP-alpha	NP_001259218.1	IG_like	49..129	CDD:214653
		Ig	51..131	CDD:299845
		I-set	144..240	CDD:254352	38/98 (39%)
		IGc2	159..228	CDD:197706	30/68 (44%)
		Ig	244..337	CDD:299845	31/93 (33%)
		I-set	244..337	CDD:254352	31/93 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	50	1.000	Domainoid score	I11661
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm26286
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920