DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6867 and OLFML1

DIOPT Version :9

Sequence 1:	NP_573262.2	Gene:	CG6867 / 32782	FlyBaseID:	FBgn0030887	Length:	949	Species:	Drosophila melanogaster
Sequence 2:	NP_001357427.1	Gene:	OLFML1 / 283298	HGNCID:	24473	Length:	402	Species:	Homo sapiens

Alignment Length:	248	Identity:	67/248 - (27%)
Similarity:	122/248 - (49%)	Gaps:	21/248 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   704 KVVNEKFGSWLRDPSPDSDREKTFVTNENDPYNLFEFTT-RIQYRMNSIPR-RKYEIQEGFHGNA 766
            |.:.:..|||::|...:|.:....:.:.|:  .::||.. |.....|:.|. ||..:...:.|..
Human   155 KKMMDTHGSWMKDAVYNSPKVYLLIGSRNN--TVWEFANIRAFMEDNTKPAPRKQILTLSWQGTG 217

  Fly   767 HVVFNG-SFYYQQRNSDLVVKLDLTSLKKITTQ----LPYAGVAAANRLYTTDYNYMDFNVDEVG 826
            .|::.| .|::.|..|:.::|.   :|:|.|.:    || .||..|.....:...|:|..|||.|
Human   218 QVIYKGFLFFHNQATSNEIIKY---NLQKRTVEDRMLLP-GGVGRALVYQHSPSTYIDLAVDEHG 278

  Fly   827 LWVIYSTYNSNNTLV-AKLDAETLKMQYNFNITLDHHQFGEMFIVCGNLYAI-DSGTDKNTQIRY 889
            ||.|:|...:::.|| .|::..||.::::::...........|::||.||.: .:|.....:|..
Human   279 LWAIHSGPGTHSHLVLTKIEPGTLGVEHSWDTPCRSQDAEASFLLCGVLYVVYSTGGQGPHRITC 343

  Fly   890 VVDLYKGKLLNTNLPF----SNPFSHTTTVGYNPLTVELYSWDKGNALTYPIR 938
            :.|.. |.:...:||.    ..|.|| :.:.|||...:||:|::||.:.|.::
Human   344 IYDPL-GTISEEDLPNLFFPKRPRSH-SMIHYNPRDKQLYAWNEGNQIIYKLQ 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6867	NP_573262.2	Collagen	306..364	CDD:189968
		IG_like	442..525	CDD:214653
		IGc2	449..511	CDD:197706
		IG_like	544..612	CDD:214653
		Ig	546..612	CDD:143165
		OLF	694..937	CDD:280371	67/245 (27%)
OLFML1	NP_001357427.1	OLF	145..393	CDD:334840	67/245 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23192
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910