DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6867 and Myoc

DIOPT Version :9

Sequence 1:	NP_573262.2	Gene:	CG6867 / 32782	FlyBaseID:	FBgn0030887	Length:	949	Species:	Drosophila melanogaster
Sequence 2:	NP_034995.3	Gene:	Myoc / 17926	MGIID:	1202864	Length:	490	Species:	Mus musculus

Alignment Length:	321	Identity:	89/321 - (27%)
Similarity:	146/321 - (45%)	Gaps:	28/321 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   646 PESECPVCDQCP----------DPSLYQCKDSILNNFEIQATGNL--SYPGLPKR---PKTC-YL 694
            |.::.|..|..|          |...:|...|.|.  |:.|:..|  :..|.|:.   .|.| .|
Mouse   172 PSTQYPSQDMLPGSREVSQWNLDTLAFQELKSELT--EVPASQILKENPSGRPRSKEGDKGCGAL 234

  Fly   695 YAVGKPV---FHKVVNEKFGSWLRDPSPDS--DREKTF--VTNENDPYNLFEFTTRIQYRMNSIP 752
            ..||:||   ..:.:..|:|.|:|||.|..  .:|.|:  .|...:...:||::...|:. ...|
Mouse   235 VWVGEPVTLRTAETIAGKYGVWMRDPKPTHPYTQESTWRIDTVGTEIRQVFEYSQISQFE-QGYP 298

  Fly   753 RRKYEIQEGFHGNAHVVFNGSFYYQQRNSDLVVKLDL-TSLKKITTQLPYAGVAAANRLYTTDYN 816
            .:.:.:.........||:.||.|:|...|..||:.:| |...|...::|.||...........|.
Mouse   299 SKVHVLPRALESTGAVVYAGSLYFQGAESRTVVRYELDTETVKAEKEIPGAGYHGHFPYAWGGYT 363

  Fly   817 YMDFNVDEVGLWVIYSTYNSNNTLV-AKLDAETLKMQYNFNITLDHHQFGEMFIVCGNLYAIDSG 880
            .:|..|||.||||||||..:...:| :||:...|:::..:...:........|::||.||.:.|.
Mouse   364 DIDLAVDESGLWVIYSTEEAKGAIVLSKLNPANLELERTWETNIRKQSVANAFVICGILYTVSSY 428

  Fly   881 TDKNTQIRYVVDLYKGKLLNTNLPFSNPFSHTTTVGYNPLTVELYSWDKGNALTYPIRYNE 941
            :..:..:.:..|...|......:||:|.:.:::.:.||||..:|::||..|.:||.|:..|
Mouse   429 SSAHATVNFAYDTKTGTSKTLTIPFTNRYKYSSMIDYNPLERKLFAWDNFNMVTYDIKLLE 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6867	NP_573262.2	Collagen	306..364	CDD:189968
		IG_like	442..525	CDD:214653
		IGc2	449..511	CDD:197706
		IG_like	544..612	CDD:214653
		Ig	546..612	CDD:143165
		OLF	694..937	CDD:280371	72/251 (29%)
Myoc	NP_034995.3	RILP-like	<97..176	CDD:304877	1/3 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	153..184		3/11 (27%)
		OLF	232..489	CDD:128580	73/257 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	126	1.000	Domainoid score	I5381
eggNOG	1	0.900	-	-		E1_KOG3545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23192
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3311
SonicParanoid	1	1.000	-	-		X205
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.940