DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6867 and Adgrl2

DIOPT Version :9

Sequence 1:NP_573262.2 Gene:CG6867 / 32782 FlyBaseID:FBgn0030887 Length:949 Species:Drosophila melanogaster
Sequence 2:NP_599235.3 Gene:Adgrl2 / 171447 RGDID:620835 Length:1487 Species:Rattus norvegicus


Alignment Length:402 Identity:96/402 - (23%)
Similarity:163/402 - (40%) Gaps:94/402 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   584 EGFKTTMRLTISNL---------RKDDFGYYHCVARNELNATMVNFEIAPQDP----NSETPYVG 635
            ||:...:|...|::         |.||                   :|...||    |::. |:.
  Rat    43 EGYSIDLRCPGSDVIMIESANYGRTDD-------------------KICDADPFQMENTDC-YLP 87

  Fly   636 NNMKVYGQR-PPESECPVC-------DQCPDPSLYQCKDSILNNFEIQATGNLSYPGLPKRPKTC 692
            :..|:..|| ...::|.|.       |.||....|         .|:|      |..:|...:..
  Rat    88 DAFKIMTQRCNNRTQCVVVTGSDVFPDPCPGTYKY---------LEVQ------YECVPYMEQKV 137

  Fly   693 YL------YAVGKPVFHKVVNEKFGSWLRDPSPDSDREKTFVTNENDPYNLFEFTTRIQYR---- 747
            ::      ..|..|..:: ..:|.|:|.:||...:|  |.:..    |:..:...|.|:|.    
  Rat   138 FVCPGTLKAIVDSPSIYE-AEQKAGAWCKDPLQAAD--KIYFM----PWTPYRTDTLIEYASLED 195

  Fly   748 -MNSIPRRKYEIQEGFHGNAHVVFNGSFYYQQRNSDLVVKLDL-TSLKKITTQLPYAGVAAANRL 810
             .||.....|::.....|...||::|:.::.:..:..:||.|| |.:|.....:.|     ||..
  Rat   196 FQNSRQTTTYKLPNRVDGTGFVVYDGAVFFNKERTRNIVKFDLRTRIKSGEAIINY-----ANYH 255

  Fly   811 YTTDYNY-----MDFNVDEVGLWVIYSTYNSNNTLV-AKLDAETLKMQYNFNITLDHHQFGEMFI 869
            .|:.|.:     :|..|||.||||||:|..:|..:| ::|:..||:.:..:..|.|.......|:
  Rat   256 DTSPYRWGGKTDIDLAVDENGLWVIYATEQNNGMIVISQLNPYTLRFEATWETTYDKRAASNAFM 320

  Fly   870 VCGNLYAI-------DSGTDKNTQIRYVVDLYKGKLLNTNLPFSNPFSHTTTVGYNPLTVELYSW 927
            :||.||.:       :|...||. |.|:.:....:..:.::||.|.:.:...|.|||...:||.|
  Rat   321 ICGVLYVVRSVYQDNESEAGKNV-IDYIYNTRLSRGEHVDVPFPNQYQYIAAVDYNPRDNQLYVW 384

  Fly   928 DKGNALTYPIRY 939
            :....|.|.:.:
  Rat   385 NNNFILRYSLEF 396

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6867NP_573262.2 Collagen 306..364 CDD:189968
IG_like 442..525 CDD:214653
IGc2 449..511 CDD:197706
IG_like 544..612 CDD:214653 7/36 (19%)
Ig 546..612 CDD:143165 7/36 (19%)
OLF 694..937 CDD:280371 71/267 (27%)
Adgrl2NP_599235.3 Gal_Lectin 49..129 CDD:396628 22/114 (19%)
OLF 142..398 CDD:413369 71/268 (26%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 422..462
HormR 469..533 CDD:214468
GAIN 542..764 CDD:406802
GPS 788..840 CDD:197639
7tm_GPCRs 848..1129 CDD:421689
TM helix 1 850..875 CDD:410628
TM helix 2 884..906 CDD:410628
TM helix 3 915..942 CDD:410628
TM helix 4 954..974 CDD:410628
TM helix 5 991..1020 CDD:410628
TM helix 6 1036..1087 CDD:410628
TM helix 7 1091..1116 CDD:410628
Latrophilin 1128..1487 CDD:396778
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1139..1160
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1386..1428
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 127 1.000 Domainoid score I5230
eggNOG 1 0.900 - - E1_KOG3545
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
43.810

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