DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6867 and si:ch211-194m7.4

DIOPT Version :9

Sequence 1:	NP_573262.2	Gene:	CG6867 / 32782	FlyBaseID:	FBgn0030887	Length:	949	Species:	Drosophila melanogaster
Sequence 2:	XP_002666846.2	Gene:	si:ch211-194m7.4 / 100331859	ZFINID:	ZDB-GENE-131125-83	Length:	449	Species:	Danio rerio

Alignment Length:	469	Identity:	107/469 - (22%)
Similarity:	183/469 - (39%)	Gaps:	93/469 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   523 VEVQFAPMISVYRQMIYAEYQSSATLECLVEA----FPEAIRYWERAYD----GKILDPSDKYGI 579
            ||.|..|.:           |.:.:..|.:.:    || |:::.|....    .:|||..::..|
Zfish    14 VEAQRVPGL-----------QKTDSCLCKINSSIWTFP-AVQFMEVTRQVQVCEEILDEFEEKVI 66

  Fly   580 ESYPE--GFKTTMRLTISNLRKDDF----GYYHCVARNELNATMVNF-----EIAPQDPNSETPY 633
            .:..|  ..:.|::...|.|:..|:    |.|..:...:||..:...     |...|:|..||..
Zfish    67 NTNAELPMMEATLQNITSRLKPFDYLYKSGLYSALYLRQLNQELEEIHRSVSETHMQNPKKETRT 131

  Fly   634 V---GNNMKVYGQRPPESECPVCDQCPDPSLYQCKDSILNNFEIQATGNLSYPGLPKRPKT---- 691
            :   .|..|...|:                :|  ||..   |.:::..| ....|..|.:|
Zfish   132 LLRELNKTKKDAQK----------------MY--KDDF---FNLESMKN-RLRDLNNRAQTSKTM 174

  Fly   692 -------CY---LYAVGKPVFHKV--VNEKF--GSWLRDP-SPDSDR--EKTFVTNEND-----P 734
                   |:   :..:..||..|:  :::.:  |:|.||. ..|.:|  |...|:...|     .
Zfish   175 PTDFRSSCHQRIMTRISSPVVTKLNSISKSYISGAWGRDALLTDKERYWEHCLVSGHKDGHTIRM 239

  Fly   735 YNLFE-FTTRIQYRMNSIPRRKYEIQEGFHGNAHVVFNGSFYYQQRNSDLVVKLDLTSLKKITTQ 798
            ||.:| |.....|:...| ...|..:....|:..:::|.:.|||..:...:...|:||  :.|.:
Zfish   240 YNSYEDFMANRNYKDEQI-APSYSSKNAVRGSGTILYNNTVYYQCYDKAEICSFDITS--QSTKR 301

  Fly   799 LPYAGVAAANRL----YT-TDYNYMDFNVDEVGLWVIYST-YNSNNTLVAKLDAETLKMQYNFNI 857
            :...|....|:.    |: .|:..:|...|...:||||:| .|..|.::::||...|.:.:.|..
Zfish   302 MKLDGAGIDNKFPFCYYSCRDWTDIDLEADRDAVWVIYATEENHGNIILSRLDPVELNITHTFKT 366

  Fly   858 TLDHHQFGEMFIVCGNLYAIDSGTDKNTQIRYVVDLYKGKLLNT-NLPFSNPFSHTTTVGYNPLT 921
            .|........|:|||.|||.........::.|..|...|:.:|: :|||....:....:.|||..
Zfish   367 HLFKRSVSSTFMVCGVLYATRYVNTYQEEVFYAFDTTTGQEINSLSLPFEKVSAGIANLNYNPAD 431

  Fly   922 VELYSWDKGNALTY 935
            ..||.::....|.|
Zfish   432 DRLYLYNDAYLLAY 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6867	NP_573262.2	Collagen	306..364	CDD:189968
		IG_like	442..525	CDD:214653	1/1 (100%)
		IGc2	449..511	CDD:197706
		IG_like	544..612	CDD:214653	16/81 (20%)
		Ig	546..612	CDD:143165	16/79 (20%)
		OLF	694..937	CDD:280371	67/262 (26%)
si:ch211-194m7.4	XP_002666846.2	OLF	188..446	CDD:280371	67/261 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23192
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010