Protein Alignment Sh and kcnv2b

DIOPT Version :10

• Sequence 1: NP_728123.1
• Gene: Sh / 32780
• FlyBaseID: FBgn0003380
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_001122212.1
• Gene: kcnv2b / 567780
• ZFINID: ZDB-GENE-060526-28
• Length: 527
• Species: Danio rerio
• Alignment Length: 464
• Identity: 132/464 - (28%)
• Similarity: 211/464 - (45%)
• Gaps: 101/464 - (21%)

  Fly   101 INVSGLRFETQLRTLNQFPDTLLGDPARRLRYFDPLR-------------NEYFFDRSRPSFDAI 152
            :||.|..:....:...::|.|.||    ||.....|.             |||||||....|::|
Zfish    84 LNVGGKSYRITYKMAARYPQTRLG----RLAMSTDLNMKMDLCDDYVVKDNEYFFDRDPDVFNSI 144

  Fly   153 LYYYQSGGRLRRPVNVPLDVFSEEIKFY--------------------ELGDQ-AINKFREDEGF 196
            ..:|::|....:....|.: |.|||.::                    ||.:| .:.|..|.|..
Zfish   145 FNFYRTGVLWIKDELCPRN-FLEEISYWGVRIKYSQRCCRILLEEKNDELCEQLKVQKELERELE 208

  Fly   197 IKEEERPLPD---NEKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYKVF 258
            |:|.|....|   .|.:|.:|...|.|.||..|:::|:.|...:|:|:|...|.|:.|.:
Zfish   209 IEENEEAFDDMILGESRRSLWDFMEKPFSSIPAKLMAVTSSMFVLISLVTMTLSTVEEME----- 268

  Fly   259 NTTTNGTKIEEDEVPDITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPY 323
            |..:.|....|           .:|.|||.:||.|..:|.::.|:...|.:.::|.:|::||:|.
Zfish   269 NIESEGKNYGE-----------FVENLCITFFTIEYLLRVISTPDICRFFKSMLNAVDLMAILPQ 322

  Fly   324 FITLATVVAEEEDTLNLPKAPVSPQDKSSNQAMSL----------AILRVIRLVRVFRIFKLSRH 378
            .:..   :.|..:|..           |.||:..:          .:||::||:|:||:.||:||
Zfish   323 ILQF---MLENFETFG-----------SRNQSADMETVGQVGKVGQVLRIMRLLRIFRVLKLARH 373

  Fly   379 SKGLQILGRTLKASMRELGLLIFFLFIGVVLFSSAVYFAEAGSENSFFKSIPDAFWWAVVTMTTV 443
            |.||:..|.|||...:::|.|..|:.:|:..||:.||..|.....:.|.|||.::|||.|:::||
Zfish   374 STGLRAFGFTLKQCYQQVGCLFLFIAMGIFTFSAMVYSVEYDVPKTNFTSIPHSWWWASVSISTV 438

  Fly   444 GYGDMTPVGVWGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDQEEMQSQNFNHVTSCPYL 508
            |||||.|..:.|:|....|...|::...||:.::.:.|:.:|.:....|            ||
Zfish   439 GYGDMYPETLLGRIFAFGCISFGIILNGLPISILFNKFSDYYAKLKSHE------------CP-- 489

  Fly   509 PGTLGQHMK 517
                 .|||
Zfish   490 -----SHMK 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sh	NP_728123.1	BTB_POZ	97..223	CDD:453885	41/158 (26%)
		Ion_trans	226..488	CDD:459842	83/271 (31%)
kcnv2b	NP_001122212.1	BTB_POZ	82..189	CDD:453885	26/109 (24%)
		Ion_trans	241..484	CDD:459842	83/272 (31%)