Protein Alignment Sh and kcnc1a

DIOPT Version :9

• Sequence 1: NP_001303569.1
• Gene: Sh / 32780
• FlyBaseID: FBgn0003380
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: XP_005168950.1
• Gene: kcnc1a / 565419
• ZFINID: ZDB-GENE-061220-10
• Length: 609
• Species: Danio rerio
• Alignment Length: 488
• Identity: 178/488 - (36%)
• Similarity: 256/488 - (52%)
• Gaps: 107/488 - (21%)

  Fly    97 ERVVINVSGLRFETQLRTLNQFPDT---LLGDPARRLRY-FDPLRNEYFFDRSRPSFDAILYYYQ 157
            :||||||.|:|.:|...||...|.|   .|.:|.....: :|...:|:||||....|..||.||:
Zfish     8 DRVVINVGGIRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDAQIDEFFFDRHPGVFAHILNYYR 72

  Fly   158 SGGRLRRPVNVPLDVFSEEIKFYEL------------------GDQAINKF--------RED--- 193
            : |:|..|.:|...::.||:.|:.:                  .::|::.|        .:|
Zfish    73 T-GKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHREAEEALDSFGGGPVEMGNDDMDT 136

  Fly   194 -------EGFIKEEERPL---------PDNEK-------QRKVWLLFEYPESSQAARVVAIISVF 235
                   :|   :||..:         ||.:.       ||:||.|||.|.||:.||.||..|:|
Zfish   137 EALGDPGDG---DEELEMTKRLAVGDSPDTKGAGFWQRWQRRVWALFEDPYSSKYARWVAFASLF 198

  Fly   236 VILLSIVIFCLETLPEFKHYKVFNTTTNGTKIEEDEVPDITDPFFL----------IETLCIIWF 290
            .||:||..|||||      ::.||...|.|.:   ...|.|..|.|          ||.:|::||
Zfish   199 FILVSITTFCLET------HEAFNPIINRTYV---NTQDNTSRFHLETETVVYLTYIEGVCVVWF 254

  Fly   291 TFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYFITLATVVAEEEDTLNLPKAPVSPQDKSSNQA 355
            |||..:|...||:|..|.::.:|:||.:||:|:::                  .|.....||::|
Zfish   255 TFEFLMRVTFCPDKKKFIKNTLNIIDFVAILPFYL------------------EVGLSGLSSSEA 301

  Fly   356 MS-LAILRVIRLVRVFRIFKLSRHSKGLQILGRTLKASMRELGLLIFFLFIGVVLFSSAVYFAE- 418
            .. |..|||:|.||:.|||||:||..||::||.||:||..|..|||.||.:||::|::.:|:||
Zfish   302 KDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAER 366

  Fly   419 --------AGSDSSFFKSIPDGFWWAVVTMTTVGYGDMRPVGVWGKIVGSLCAIAGVLTIALPVP 475
                    ..|:.:.||:||.|||||||||||:|||||.|....|.:||:|||:|||||||:|||
Zfish   367 IGANPNDPRASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVP 431

  Fly   476 VIVSNFNYFYHRETDQEEMQSQNFNHVTSCPYL 508
            |||:||..:|.....::::..:...|:...|.|
Zfish   432 VIVNNFGMYYSLAMAKQKLPKKKNKHIPRAPQL 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sh	NP_001303569.1	BTB_2	99..187	CDD:280393	32/109 (29%)
		BTB	99..182	CDD:197585	32/86 (37%)
		Ion_trans	274..488	CDD:278921	105/233 (45%)
		Ion_trans_2	403..479	CDD:285168	47/84 (56%)
kcnc1a	XP_005168950.1	BTB	10..112	CDD:197585	32/102 (31%)
		BTB_2	10..104	CDD:280393	32/94 (34%)
		Ion_trans	243..445	CDD:278921	101/219 (46%)
		Ion_trans_2	<388..435	CDD:285168	35/46 (76%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810