Protein Alignment Sh and kcnf1a

DIOPT Version :9

• Sequence 1: NP_001303569.1
• Gene: Sh / 32780
• FlyBaseID: FBgn0003380
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_001076280.1
• Gene: kcnf1a / 557280
• ZFINID: ZDB-GENE-041001-217
• Length: 494
• Species: Danio rerio
• Alignment Length: 483
• Identity: 144/483 - (29%)
• Similarity: 236/483 - (48%)
• Gaps: 95/483 - (19%)

  Fly    99 VVINVSGLRFETQLRTLNQFPDTLLGDPARRLR-----------YFDPLRNEYFFDRSRPSFDAI 152
            :.:|:.|::.......||::|:|.|.:...|:.           .:|.|:.|::|||...:|..|
Zfish    23 ISVNIGGVKHTLYGDVLNRYPETRLAELLNRVSDSAEDLSGLCDDYDDLKREFYFDRDPKAFKCI 87

  Fly   153 --LYYYQSGGRLRRPVNVPLDVFSEEIKFYELGDQ--------AINKFREDEGFIKEEERPLPDN 207
              ||||   |.:.....:....|.:|:.::.:.:.        ::|:...:...|.|:.:.:.|:
Zfish    88 LELYYY---GEIHMKRGICPMCFMKEMDYWGIDEDYLDECCRCSLNEVETELAEIAEKVKTILDD 149

  Fly   208 EK----------------QRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYK 256
            .:                |..:|.|.|.||||.||||:|::|...||||.|:.|:.|:||.
Zfish   150 LEDDDDDDDARVSRSQRCQTFLWKLMEKPESSVAARVIAVVSFVFILLSSVVMCVGTIPEL---- 210

  Fly   257 VFNTTTNGTKIEEDEVPDITDPFF-LIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAI 320
                     ::::||......|.. .|||.||||||.|..:|..:..:||:|....:|:||.:||
Zfish   211 ---------QVQDDEGHLTEHPTLEAIETACIIWFTVEYVLRLASSSSKLHFVFSFLNIIDFLAI 266

  Fly   321 IPYFIT-----LATVVAEEEDTLNLPKAPVSPQDKSSNQAMSLAILRVIRLVRVFRIFKLSRHSK 380
            :|:::.     |.|.:.|   ..|:.:|                 ::.:|::|:.|||||:|||.
Zfish   267 MPFYVVLILTHLGTAMME---LANVQQA-----------------VQALRIMRIARIFKLARHSS 311

  Fly   381 GLQILGRTLKASMRELGLLIFFLFIGVVLFSSAVYFAEAGSDSSFFKSIPDGFWWAVVTMTTVGY 445
            |||.|...||:|::|||||:.::.:|:.|||:..|..|.....:.|.|||..||||::|||||||
Zfish   312 GLQTLTFALKSSLKELGLLLMYMSVGIFLFSALGYTMEQSHPETMFTSIPQSFWWAIITMTTVGY 376

  Fly   446 GDMRPVGVWGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET--------DQEEMQSQNFNHV 502
            ||:.|....|:...::..:.||:.||||:..|::||...|.::.        :.|.|..:.....
Zfish   377 GDIYPKTTLGRCNAAVSFLCGVIAIALPIHPIINNFVIVYSKQRVLETAAKHEIELMALRAREEA 441

  Fly   503 TSCPYLPGTLGQHMKKSSLSESSSDMMD 530
            ..||        ..::.:.|..||.|.|
Zfish   442 QECP--------EAERRAASVDSSSMWD 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sh	NP_001303569.1	BTB_2	99..187	CDD:280393	23/108 (21%)
		BTB	99..182	CDD:197585	23/95 (24%)
		Ion_trans	274..488	CDD:278921	83/219 (38%)
		Ion_trans_2	403..479	CDD:285168	32/75 (43%)
kcnf1a	NP_001076280.1	BTB_2	23..124	CDD:308049	23/103 (22%)
		Ion_trans	184..420	CDD:306908	99/268 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000074
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.810