Protein Alignment Sh and kcnb1

DIOPT Version :9

• Sequence 1: NP_001303569.1
• Gene: Sh / 32780
• FlyBaseID: FBgn0003380
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: XP_021332945.1
• Gene: kcnb1 / 555284
• ZFINID: ZDB-GENE-090831-3
• Length: 834
• Species: Danio rerio
• Alignment Length: 595
• Identity: 198/595 - (33%)
• Similarity: 294/595 - (49%)
• Gaps: 119/595 - (20%)

  Fly    98 RVVINVSGLRFETQLRTLNQFPDTLLGDPARRLRYFDPLR----------NEYFFDRSRPSFDAI 152
            ||.:||.||..|...|||::.|.|.|| ..|..:..:.|.          |||||||...:|.:|
Zfish    35 RVKLNVGGLPHEVLWRTLDRLPRTRLG-KLRDCKTHESLMEVCDDYNLEDNEYFFDRHPGAFTSI 98

  Fly   153 LYYYQSGGRLRRPVNVPLDVFSEEI----------------KFYELGDQAINKFREDEGFIKEEE 201
            |.:|:: |:|.....:....||:|:                ::::..:|...:.:.:...:|:.|
Zfish    99 LNFYRT-GKLHMMEEMCALSFSQELDYWGVDEIYLESCCQARYHQKKEQMNEELKREADTLKDRE 162

  Fly   202 RPLPDN----EKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYKVFNTTT 262
            ....||    ||::|:|.|.|.|.||.||:::||||:..|:||.:...|.||||.:....|..||
Zfish   163 GEEFDNTCCSEKRKKLWDLLEKPGSSVAAKILAIISILFIVLSTIALSLNTLPELQETDEFGQTT 227

  Fly   263 NGTKIEEDEVPDITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYFITL 327
            :.|::..            :|.:||.|||.|..:|||:.|||..|.:..:||||::||:||::|:
Zfish   228 DNTQLAH------------VEAVCIAWFTMEYLLRFLSSPNKWKFFKGPLNVIDLLAILPYYVTI 280

  Fly   328 ATVVAEEEDTLNLPKAPVSPQDKSSNQAMSL-AILRVIRLVRVFRIFKLSRHSKGLQILGRTLKA 391
            .                ::..:||..|..:: .::::.|::|:.||.||:|||.|||.||.||:.
Zfish   281 F----------------LTESNKSVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRR 329

  Fly   392 SMRELGLLIFFLFIGVVLFSSAVYFAEAGSDSSFFKSIPDGFWWAVVTMTTVGYGDMRPVGVWGK 456
            |..||||||.||.:|:::|||.|:|||...|.:.|||||..||||.:|||||||||:.|..:.||
Zfish   330 SYNELGLLILFLAMGIMIFSSLVFFAEKDEDDTKFKSIPASFWWATITMTTVGYGDIYPKTLLGK 394

  Fly   457 IVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDQE---------EMQSQNFNHVTSCPYLPGTL 512
            |||.||.|||||.||||:|:||:||:.||..:..||         |...:|.:.|:
Zfish   395 IVGGLCCIAGVLVIALPIPIIVNNFSEFYKEQKRQEKAIKRREALERAKRNGSIVS--------- 450

  Fly   513 GQHMKKSSLSESSSDMMD---LDDGVES-----TP---------GLTETHPGRSAVAPFLGAQQQ 560
               |.........:|::|   :|.|..|     :|         |.:||...||    |...|..
Zfish   451 ---MNVREAFSRGTDLLDVVVMDKGERSQDNHLSPSRWKWSSKRGTSETSSNRS----FNPDQGS 508

  Fly   561 QQQPVASSLSMSIDKQLQHPLQQLTQTQLYQQQQQQQQQQQNGFKQQQQQTQQQLQQQQSHTINA 625
            ..:..|||......::|:....|:.:||                .|....|:.:...:..|..:.
Zfish   509 PSKARASSPQRLNAQKLEDMYNQMAKTQ----------------SQPNLNTKDRNSSRAGHRRDE 557

  Fly   626 SAAAATSGSG 635
            ....|..|.|
Zfish   558 IELGALPGQG 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sh	NP_001303569.1	BTB_2	99..187	CDD:280393	32/113 (28%)
		BTB	99..182	CDD:197585	31/108 (29%)
		Ion_trans	274..488	CDD:278921	102/214 (48%)
		Ion_trans_2	403..479	CDD:285168	47/75 (63%)
kcnb1	XP_021332945.1	BTB_2	36..135	CDD:308049	31/100 (31%)
		Ion_trans	191..427	CDD:306908	119/263 (45%)
		Kv2channel	470..712	CDD:308887	24/118 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910