Protein Alignment Sh and Shab

DIOPT Version :9

• Sequence 1: NP_001303569.1
• Gene: Sh / 32780
• FlyBaseID: FBgn0003380
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Alignment Length: 915
• Identity: 241/915 - (26%)
• Similarity: 363/915 - (39%)
• Gaps: 327/915 - (35%)

  Fly    12 EDRQHRKKQQQQQQHQKEQLEQKEEQKKIAERKLQLREQQL----------------------QR 54
            :.:||.|:||||||.|::||:.|:.|::..:...|...:.:                      ..
  Fly    52 QQQQHSKQQQQQQQQQQQQLQLKQHQQQQQDILYQQHNEAIAIARGLQAATPADIGDNQPYYDTS 116

  Fly    55 NSLD----------------GYGSLP-------KLSSQDEEG----------------------- 73
            .::|                |.||||       .|...:..|
  Fly   117 GNVDWERAMGAGGAGAYGGIGIGSLPAAGGAAYHLGPANPAGLVSRHLDYGDGGHLAGPSAGLPA 181

  Fly    74 ------------------------------GAGHGFGGG---------------PQHFEP----- 88
                                          |||.|.|.|               |.|..|
  Fly   182 GAVGSGAGAGAGAGASVTGSGSGAGTGTGTGAGSGSGSGAAGKEVRYAPFPVASPTHSIPTTSQQ 246

  Fly    89 --------------------------------------------IPHDHDFC--------ERVVI 101
                                                        ||....|.        .||.|
  Fly   247 IVGSVGGVGVGGASSQSISGGVPTHSQSNTTGALQRTHSRSMSSIPPPEPFMIAQSKAVNSRVSI 311

  Fly   102 NVSGLRFETQLRTLNQFPDTLLGDPARRLRY-------------FDPLRNEYFFDRSRPSFDAIL 153
            ||.|:|.|...|||.:.|.|.||    |||.             :....|||||||...||.:||
  Fly   312 NVGGVRHEVLWRTLERLPHTRLG----RLRECTTHEAIVELCDDYSLADNEYFFDRHPKSFSSIL 372

  Fly   154 YYYQSGGRLRRPVNVPLDVFSEEIKFYELGDQAI-----NKFREDEGFIKEEERPLPDN------ 207
            .:|:: |:|.....:.:..||::::::.:.:..:     :|:.:.:..:.||.|...::
  Fly   373 NFYRT-GKLHIVDEMCVLAFSDDLEYWGVDELYLESCCQHKYHQRKENVHEEMRKEAESLRQRDE 436

  Fly   208 ---------EKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYKVFNTTTN 263
                     |.|:.:|.|.|.|.:|.||||:|:||:..|:||.:...|.|||:.:|      ..|
  Fly   437 EEFGEGKCAEYQKYLWELLEKPNTSFAARVIAVISILFIVLSTIALTLNTLPQLQH------IDN 495

  Fly   264 GTKIEEDEVPDITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYFITLA 328
            ||       |.......::|.:||.|||.|..:||.|.|:|..|.:..:|:||::||:|||::|.
  Fly   496 GT-------PQDNPQLAMVEAVCITWFTLEYILRFSASPDKWKFFKGGLNIIDLLAILPYFVSLF 553

  Fly   329 TVVAEEEDTLNLPKAPVSPQDKSSNQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGRTLKASM 393
            .:...:..|...       ||..       .:::|.|::|:.||.||:|||.|||.||.||:.|.
  Fly   554 LLETNKNATDQF-------QDVR-------RVVQVFRIMRILRILKLARHSTGLQSLGFTLRNSY 604

  Fly   394 RELGLLIFFLFIGVVLFSSAVYFAEAGSDSSFFKSIPDGFWWAVVTMTTVGYGDMRPVGVWGKIV 458
            :|||||:.||.:||::|||..||||.....:.|.|||:.||||.:|||||||||:.|....||::
  Fly   605 KELGLLMLFLAMGVLIFSSLAYFAEKDEKDTKFVSIPETFWWAGITMTTVGYGDIYPTTALGKVI 669

  Fly   459 GSLCAIAGVLTIALPVPVIVSNFNYFYHRETDQEEMQSQ--------------NFNHVTSCPYLP 509
            |::|.|.|||.||||:|:||:||..||..:..:|:...:              :|:|:
  Fly   670 GTVCCICGVLVIALPIPIIVNNFAEFYKNQMRREKALKRREALDRAKREGSIVSFHHI------- 727

  Fly   510 GTLGQHMKKSSLSESSSDMMDLDDGVESTPGLTE-THP-GRSAVAPFLGAQ--QQQQQP------ 564
                      :|.::.:..|||.|.:..|...|. .|| |:....|.:|.|  ..|..|
  Fly   728 ----------NLKDAFAKSMDLIDVIVDTGKQTNVVHPKGKRQSTPNIGRQTLDVQSAPGHNLSQ 782

  Fly   565 -----------------------------VASSLSMSIDKQLQHPLQQ------------LTQTQ 588
                                         ||:..:.::..:.....:|            ..||.
  Fly   783 TDGNSTEGESTSGRNPATTGTGCYKNYDHVANLRNSNLHNRRGSSSEQDAVPPYSFDNPNARQTS 847

  Fly   589 L-----YQQQQQQQQQQQNGFKQQQQQTQQQLQQQQSHTINASAAAATSGSGSSGLTMRHNNALA 648
            :     |:::||...|||    |||||...|:||.|....|.: ..||.|..::.|.|...::.|
  Fly   848 MMAMESYRREQQALLQQQ----QQQQQQMLQMQQIQQKAPNGN-GGATGGGVANNLAMVAASSAA 907

  Fly   649 VSIET 653
            .::.|
  Fly   908 TAVAT 912

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sh	NP_001303569.1	BTB_2	99..187	CDD:280393	33/100 (33%)
		BTB	99..182	CDD:197585	33/95 (35%)
		Ion_trans	274..488	CDD:278921	96/213 (45%)
		Ion_trans_2	403..479	CDD:285168	42/75 (56%)
Shab	NP_001189037.1	BTB	309..416	CDD:197585	34/111 (31%)
		BTB_2	309..408	CDD:280393	33/103 (32%)
		Ion_trans	501..700	CDD:278921	96/212 (45%)
		Ion_trans_2	613..696	CDD:285168	46/82 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11537
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
	4	3.910