Protein Alignment Sh and Kcnf1

DIOPT Version :9

• Sequence 1: NP_001303569.1
• Gene: Sh / 32780
• FlyBaseID: FBgn0003380
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_963289.2
• Gene: Kcnf1 / 382571
• MGIID: 2687399
• Length: 505
• Species: Mus musculus
• Alignment Length: 492
• Identity: 152/492 - (30%)
• Similarity: 244/492 - (49%)
• Gaps: 100/492 - (20%)

  Fly    62 SLPKLSSQDEEGGAGHGFGGGPQHFEPIPHDHDFCERVVINVSGLRFETQLRTLNQFPDTLLGDP 126
            |||:..|||...|            |.|        .:|:||.|:|.......|:|:|:|.|.:.
Mouse    20 SLPEPGSQDSVAG------------EDI--------EIVVNVGGVRQVLYGDLLSQYPETRLAEL 64

  Fly   127 ARRLR--Y---------FDPLRNEYFFDRSRPSFDAIL--YYYQSGGRLRRPVNVPLDVFSEEIK 178
            ...|.  |         :||.:.|::|||...:|..::  ||:   |.:.....:....|..|:.
Mouse    65 INCLAGGYDTIFSLCDDYDPGKREFYFDRDPDAFKCVIEVYYF---GEVHMKKGICPICFKNEMD 126

  Fly   179 FYELGDQAINKFRED--EGFIKEEERPLPDNEK---------------------QRKVWLLFEYP 220
            |:::.    .||.:|  :..:.|:...|.:..:                     |:.||...|.|
Mouse   127 FWKVD----LKFLDDCCKSHLSEKREELEEIARRVQLILDDLGVDAAEGRWRRCQKCVWKFLEKP 187

  Fly   221 ESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYKVFNTTTNGTKIEEDEVPDITDPFFLIETL 285
            |||..|||||::|..:||:|.|:.|:.|:||.:     ...:.|.::|...:.:       :||.
Mouse   188 ESSCPARVVAVLSFLLILVSSVVMCMGTIPELQ-----VVDSEGNRVEHPTLEN-------VETA 240

  Fly   286 CIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYFI--TLATVVAEEEDTLNLPKAPVSPQ 348
            ||.|||.|..:|..:.||||:|....||::|::||:|:::  ||..:.|...:..|:.:|
Mouse   241 CIGWFTLEYLLRLFSSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQA----- 300

  Fly   349 DKSSNQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGRTLKASMRELGLLIFFLFIGVVLFSSA 413
                        ::.:|::|:.|||||:|||.|||.|...||.|.:|||||:.:|.:|:.:||:.
Mouse   301 ------------VQALRIMRIARIFKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFSAL 353

  Fly   414 VYFAEAGSDSSFFKSIPDGFWWAVVTMTTVGYGDMRPVGVWGKIVGSLCAIAGVLTIALPVPVIV 478
            .|..|.....:.|||||..||||::|||||||||:.|....||:..::..:.||:.||||:..|:
Mouse   354 GYTMEQSHPETLFKSIPQSFWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPII 418

  Fly   479 SNFNYFYHRE-----TDQEEMQSQNFNHVTSCPYLPG 510
            :||..:|:::     ..:.|::....|. :|....||
Mouse   419 NNFVRYYNKQRVLETAAKHELELMELNS-SSAEGKPG 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sh	NP_001303569.1	BTB_2	99..187	CDD:280393	25/100 (25%)
		BTB	99..182	CDD:197585	25/95 (26%)
		Ion_trans	274..488	CDD:278921	84/215 (39%)
		Ion_trans_2	403..479	CDD:285168	34/75 (45%)
Kcnf1	NP_963289.2	BTB_POZ_Kv5_KCNF1	35..150	CDD:349690	30/129 (23%)
		Ion_trans	193..429	CDD:366146	100/264 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000074
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810