Sequence 1: | NP_001303569.1 | Gene: | Sh / 32780 | FlyBaseID: | FBgn0003380 | Length: | 655 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_004968.2 | Gene: | KCNC3 / 3748 | HGNCID: | 6235 | Length: | 757 | Species: | Homo sapiens |
Alignment Length: | 583 | Identity: | 194/583 - (33%) |
---|---|---|---|
Similarity: | 274/583 - (46%) | Gaps: | 152/583 - (26%) |
- Green bases have known domain annotations that are detailed below.
Fly 77 HGFGGGPQHFEPIPHDHDFCERVVINVSGLRFETQLRTLNQFPDTLLG---DPARRLRY-FDPLR 137
Fly 138 NEYFFDRSRPSFDAILYYYQSGGRLRRPVNVPLDVFSEEIKFYELGDQAI--------NKFREDE 194
Fly 195 GFIKEEERPLP-----------------DNEK--------------------------------- 209
Fly 210 -----------QRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYKVFNTTT- 262
Fly 263 -----------NGTKIEEDEVPDITDPFF-LIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVI 315
Fly 316 DIIAIIPYFITLATVVAEEEDTLNLPKAPVSPQDKSSNQAMS-LAILRVIRLVRVFRIFKLSRHS 379
Fly 380 KGLQILGRTLKASMRELGLLIFFLFIGVVLFSSAVYFAE---------AGSDSSFFKSIPDGFWW 435
Fly 436 AVVTMTTVGYGDMRPVGVWGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDQEEMQSQNFN 500
Fly 501 HVTSCPYLPGTLGQHMKKSSLSESSSDMMDLDDGVESTPGLT----------------ETHPG 547 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Sh | NP_001303569.1 | BTB_2 | 99..187 | CDD:280393 | 34/91 (37%) |
BTB | 99..182 | CDD:197585 | 34/86 (40%) | ||
Ion_trans | 274..488 | CDD:278921 | 104/224 (46%) | ||
Ion_trans_2 | 403..479 | CDD:285168 | 48/84 (57%) | ||
KCNC3 | NP_004968.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..87 | 5/6 (83%) | |
Important for normal N-type inactivation. /evidence=ECO:0000269|PubMed:26997484 | 1..78 | ||||
Potassium_chann | 1..>18 | CDD:314363 | |||
BTB_KCNC1_3 | 89..202 | CDD:349721 | 36/113 (32%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 210..232 | 2/21 (10%) | |||
Ion_trans | 289..550 | CDD:366146 | 126/285 (44%) | ||
Selectivity filter. /evidence=ECO:0000250 | 503..508 | 3/4 (75%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 556..613 | 8/58 (14%) | |||
PHA03247 | <637..752 | CDD:223021 | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 682..746 | ||||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_COG2126 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 1 | 1.000 | - | - | X19 | |
SwiftOrtho | 1 | 1.000 | - | - | ||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
4 | 3.810 |