| Sequence 1: | NP_001303569.1 | Gene: | Sh / 32780 | FlyBaseID: | FBgn0003380 | Length: | 655 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_002226.1 | Gene: | KCNA6 / 3742 | HGNCID: | 6225 | Length: | 529 | Species: | Homo sapiens |
| Alignment Length: | 534 | Identity: | 315/534 - (58%) |
|---|---|---|---|
| Similarity: | 370/534 - (69%) | Gaps: | 92/534 - (17%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 64 PKLSSQD-----EEGGAGHGFGGGPQHFEPIPHDHDFC---ERVVINVSGLRFETQLRTLNQFPD 120
Fly 121 TLLGDPARRLRYFDPLRNEYFFDRSRPSFDAILYYYQSGGRLRRPVNVPLDVFSEEIKFYELGDQ 185
Fly 186 AINKFREDEGFIK---EEERPLPDNEKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLE 247
Fly 248 TLPEFK---------HYKVFNTTTNGTKIEEDEVPD----------------------------I 275
Fly 276 TDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYFITLATVVAEEEDTLNL 340
Fly 341 PKAPVS-PQDKSSNQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGRTLKASMRELGLLIFFLF 404
Fly 405 IGVVLFSSAVYFAEAGSDSSFFKSIPDGFWWAVVTMTTVGYGDMRPVGVWGKIVGSLCAIAGVLT 469
Fly 470 IALPVPVIVSNFNYFYHRETDQEEMQSQNFNHVTSCPYLPGTLGQHMKKSSLSESSSDMMDLDDG 534
Fly 535 VESTPGLTETHPGR 548 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Sh | NP_001303569.1 | BTB_2 | 99..187 | CDD:280393 | 74/87 (85%) |
| BTB | 99..182 | CDD:197585 | 71/82 (87%) | ||
| Ion_trans | 274..488 | CDD:278921 | 162/242 (67%) | ||
| Ion_trans_2 | 403..479 | CDD:285168 | 64/75 (85%) | ||
| KCNA6 | NP_002226.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..33 | 4/14 (29%) | |
| BTB_POZ_KCNA6 | 41..170 | CDD:349714 | 99/128 (77%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 210..233 | 4/22 (18%) | |||
| Ion_trans | 258..468 | CDD:366146 | 161/214 (75%) | ||
| S4-S5 linker. /evidence=ECO:0000250|UniProtKB:P63142 | 360..373 | 10/12 (83%) | |||
| Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142 | 422..427 | 4/4 (100%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 488..513 | 6/22 (27%) | |||
| PDZ-binding. /evidence=ECO:0000255 | 527..529 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 362 | 1.000 | Domainoid score | I953 |
| eggNOG | 1 | 0.900 | - | - | E1_COG2126 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG48093 | |
| OrthoDB | 1 | 1.010 | - | - | D307298at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000074 | |
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 1 | 0.900 | - | - | OOG6_101149 | |
| Panther | 1 | 1.100 | - | - | O | PTHR11537 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X19 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 10 | 9.830 | |||||