| Sequence 1: | NP_001303569.1 | Gene: | Sh / 32780 | FlyBaseID: | FBgn0003380 | Length: | 655 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_002224.1 | Gene: | KCNA4 / 3739 | HGNCID: | 6222 | Length: | 653 | Species: | Homo sapiens |
| Alignment Length: | 567 | Identity: | 316/567 - (55%) |
|---|---|---|---|
| Similarity: | 402/567 - (70%) | Gaps: | 65/567 - (11%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 11 GEDRQHRKKQQQQQQHQKEQ-----------------LEQKEEQKKIAERKLQLREQQLQRNSLD 58
Fly 59 GYG---SLPKLSSQDEEGGAGHGFGGGPQHFEPIPHDHDFCERVVINVSGLRFETQLRTLNQFPD 120
Fly 121 TLLGDPARRLRYFDPLRNEYFFDRSRPSFDAILYYYQSGGRLRRPVNVPLDVFSEEIKFYELGDQ 185
Fly 186 AINKFREDEGFIKEEE-RPLPDNEKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETL 249
Fly 250 PEFK-------------HYKVFNTTTNGTKIEEDEVPDITDPFFLIETLCIIWFTFELTVRFLAC 301
Fly 302 PNKLNFCRDVMNVIDIIAIIPYFITLATVVAEEEDTLNLPKAPVSPQDKSSNQAMSLAILRVIRL 366
Fly 367 VRVFRIFKLSRHSKGLQILGRTLKASMRELGLLIFFLFIGVVLFSSAVYFAEAGSDSSFFKSIPD 431
Fly 432 GFWWAVVTMTTVGYGDMRPVGVWGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDQEEMQS 496
Fly 497 QNFNHVTSCPYLPGTLGQHMKKSSLSESS-----SDMMDLDDGVEST 538 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Sh | NP_001303569.1 | BTB_2 | 99..187 | CDD:280393 | 70/87 (80%) |
| BTB | 99..182 | CDD:197585 | 68/82 (83%) | ||
| Ion_trans | 274..488 | CDD:278921 | 149/213 (70%) | ||
| Ion_trans_2 | 403..479 | CDD:285168 | 62/75 (83%) | ||
| KCNA4 | NP_002224.1 | K_channel_TID | 1..>37 | CDD:400339 | |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 24..148 | 10/66 (15%) | |||
| BTB_POZ | 176..303 | CDD:365784 | 97/126 (77%) | ||
| Ion_trans | 306..570 | CDD:395416 | 175/274 (64%) | ||
| S4-S5 linker. /evidence=ECO:0000250|UniProtKB:P63142 | 462..475 | 10/12 (83%) | |||
| Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142 | 524..529 | 4/4 (100%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 629..653 | ||||
| PDZ-binding. /evidence=ECO:0000250 | 651..653 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 362 | 1.000 | Domainoid score | I953 |
| eggNOG | 1 | 0.900 | - | - | E1_COG2126 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 620 | 1.000 | Inparanoid score | I885 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D307298at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000074 | |
| OrthoInspector | 1 | 1.000 | - | - | otm42203 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_101149 | |
| Panther | 1 | 1.100 | - | - | O | PTHR11537 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X19 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 11 | 10.870 | |||||