Protein Alignment Sh and Kcna10

DIOPT Version :10

• Sequence 1: NP_728123.1
• Gene: Sh / 32780
• FlyBaseID: FBgn0003380
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_001178642.1
• Gene: Kcna10 / 295360
• RGDID: 1304667
• Length: 511
• Species: Rattus norvegicus
• Alignment Length: 460
• Identity: 281/460 - (61%)
• Similarity: 343/460 - (74%)
• Gaps: 45/460 - (9%)

  Fly    97 ERVVINVSGLRFETQLRTLNQFPDTLLGDPARRLRYFDPLRNEYFFDRSRPSFDAILYYYQSGGR 161
            :||:||::|||||||||||||||:|||||..:|:::||.:||||||||:|||||.|||||||||:
  Rat    86 QRVIINIAGLRFETQLRTLNQFPETLLGDREKRMQFFDSMRNEYFFDRNRPSFDGILYYYQSGGK 150

  Fly   162 LRRPVNVPLDVFSEEIKFYELGDQAINKFREDEGFIKEEERPLPDNEKQRKVWLLFEYPESSQAA 226
            :|||.|||:|||::||.|||||.:|:::|||||||||:.|..||.|:..|:.||||||||||.||
  Rat   151 IRRPANVPIDVFADEISFYELGSEAMDQFREDEGFIKDPETLLPTNDFHRQFWLLFEYPESSSAA 215

  Fly   227 RVVAIISVFVILLSIVIFCLETLPEFKHYKVFNT------TTNGTKIEEDEVPDITDPFFLIETL 285
            |.||::||.|:::||.||||||||||:..:....      .||.|.:.:..   .|||||::|:.
  Rat   216 RGVAVVSVLVVVISITIFCLETLPEFREDRELKVVRDPTINTNKTGLSQTM---FTDPFFMVEST 277

  Fly   286 CIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYFITLATVVAEEEDTLNLPKAPVSPQDK 350
            ||:||||||.:||:.||:|.:|.:::||:||||:|||||.||.|.:.:|             .:.
  Rat   278 CIVWFTFELVLRFVVCPSKPDFFKNIMNIIDIISIIPYFATLITELVQE-------------TEP 329

  Fly   351 SSNQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGRTLKASMRELGLLIFFLFIGVVLFSSAVY 415
            |:.|.|||||||:|||||||||||||||||||||||:||||||||||||||||||||:|||||||
  Rat   330 SAQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVY 394

  Fly   416 FAEAGSENSFFKSIPDAFWWAVVTMTTVGYGDMTPVGVWGKIVGSLCAIAGVLTIALPVPVIVSN 480
            |||.....|.|.||||.||||||||||||||||.|....|||||:||||||||||||||||||||
  Rat   395 FAEVDEPESHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVSN 459

  Fly   481 FNYFYHRETDQEEMQSQNFNHVTSCPYLPGTLGQHMKKSSLSESSSDMMDLDDGVESTPGLTETH 545
            |||||||||:.||.           |.:||.|.:.:  :|:...:.          ||..|.:|:
  Rat   460 FNYFYHRETENEEK-----------PNIPGELDKIL--NSMGSRTG----------STESLNKTN 501

  Fly   546 PGRSA 550
            ..|||
  Rat   502 SSRSA 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sh	NP_728123.1	BTB_POZ	97..223	CDD:453885	88/125 (70%)
		Ion_trans	226..488	CDD:459842	173/267 (65%)
Kcna10	NP_001178642.1	BTB_POZ	86..212	CDD:453885	88/125 (70%)
		Ion_trans	262..467	CDD:459842	151/220 (69%)