Protein Alignment Sh and kvs-3

DIOPT Version :9

• Sequence 1: NP_001303569.1
• Gene: Sh / 32780
• FlyBaseID: FBgn0003380
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_505407.2
• Gene: kvs-3 / 185719
• WormBaseID: WBGene00018402
• Length: 451
• Species: Caenorhabditis elegans
• Alignment Length: 422
• Identity: 127/422 - (30%)
• Similarity: 208/422 - (49%)
• Gaps: 91/422 - (21%)

  Fly   138 NEYFFDRSRPSFDAILYYYQSGGRLRRPVNV-------PLDV------FSEEIKFYELGDQAINK 189
            :||:|:||...|:.::.:|.: |:|.||:::       .||.      |.......|..:....|
 Worm    76 SEYYFERSPIIFEYVIDFYVT-GKLHRPMDICPIRLRYELDYWRIPTPFMSPCCILEENNNIAGK 139

  Fly   190 FREDEGFIKEEERPLPDN--------EKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCL 246
            ...::.|:   :..||.:        .::.|::.|.|.|.||..|::.::.|...:|||::...|
 Worm   140 MSTEKAFV---DSSLPSSCFDKVVLGPQRLKLYRLMENPRSSSGAKIFSVGSALFVLLSLLGLIL 201

  Fly   247 ETLPEFKHYKVFNTTTNGTKIEEDEVPDITDPFFL---IETLCIIWFTFELTVRFLACPNKLNFC 308
            .::||.:              :|::     :|.:|   :|.||:::||||...|.|..|.|..|.
 Worm   202 SSMPELQ--------------DENK-----EPHYLLHWLELLCMVYFTFEYLARLLVNPKKAEFI 247

  Fly   309 RDVMNVIDIIAIIPYFITLATVVAEEEDTLNLPKAPVSPQDKSSNQAM-------SLAILRVIRL 366
            |..:||||::.::|:.|                        ::.|:..       ::.::||:||
 Worm   248 RSPLNVIDLLTVLPFMI------------------------EAFNELQWMKEFRGAMLVVRVMRL 288

  Fly   367 VRVFRIFKLSRHSKGLQILGRTLKASMRELGLLIFFLFIGVVLFSSAVYFAEAGSDSSFFKSIPD 431
            .||.|||||:|:|.||:..|.|:|.|..||.:|..||..|::|||:|:||.|....:|.|.|||.
 Worm   289 ARVARIFKLARYSTGLRAFGETMKKSAAELSMLGMFLVTGIMLFSTAIYFFERDEPNSKFYSIPA 353

  Fly   432 GFWWAVVTMTTVGYGDMRPVGVWGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET------- 489
            ..||.|:|||||||||:.|:...||:|.:|.::.|::.:|.|:.:|:..|     .|:
 Worm   354 ACWWCVITMTTVGYGDLVPITAGGKVVAALASVCGIIVLAFPISMIIDKF-----AESTGGWSGG 413

  Fly   490 DQEEMQSQNFNHVTSCPYLPGT-LGQHMKKSS 520
            |.:|.|.....|.|..|...|. ..|.:||.|
 Worm   414 DGDEEQGHMIVHRTVHPLNNGAPAAQPVKKKS 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sh	NP_001303569.1	BTB_2	99..187	CDD:280393	15/61 (25%)
		BTB	99..182	CDD:197585	14/56 (25%)
		Ion_trans	274..488	CDD:278921	81/223 (36%)
		Ion_trans_2	403..479	CDD:285168	35/75 (47%)
kvs-3	NP_505407.2	BTB	26..133	CDD:197585	15/57 (26%)
		BTB_2	28..127	CDD:280393	14/51 (27%)
		Ion_trans	206..407	CDD:278921	84/248 (34%)
		Ion_trans_2	324..405	CDD:285168	37/85 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000074
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810